US5693085A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Stent with collagen
Assignee: Lifeshield Sciences LLC
•
Filing: 1995-04-26
•
Granted: 1997-12-02
•
Expires: 2015-04-26
Abstract
Abstract Collagen applied to a vascular stem for increasing the biocompatability of the stent on implantation find method of treatment.
Inventors
- 👤 Andrew W. Buirge
- 👤 Paul J. Buscemi
- 👤 Paul H. Burmeister
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 21:47
CPC Classifications
A; A61; A61M; A61M29/00; A61M29/02; A61F; A61F2/00; A61F2/0004; A61F2/0022; A61F2/02; A61F2/04; A61F2/06; A61F2/07; A61F2/82; A61F2/86; A61F2/90; A61F2/91; A61F2/915; A61F2/95; A61F2/958; A61L; A61L31/00; A61L31/08; A61L31/10; A61F2/88; A61F2/885; A61F2/89; A61F2002/072; A61F2002/075; A61F2002/828; A61F2002/91533; A61F2002/91541; A61F2002/9155; A61F2002/91558; A61F2002/9583; A61F2210/00; A61F2210/0076; A61F2220/00; A61F2220/0025; A61F2220/005; A61F2220/0058; A61F2220/0075; A61F2220/0091; A61F2250/00; A61F2250/0058; A61F2250/0067; A61M25/00; A61M25/0043; A61M25/0045; Y; Y10; Y10S; Y10S623/00; Y10S623/915; Y10S623/916; Y10S623/917
Claims Analysis
Total Claims: 43
Claim 1
Independent Claim
126 words
In combination, a vascular prostheses comprised of an expandable support framework, the expandable support framework comprising a stent, which has an expanded state having a first diameter and a compressed state having a second diameter, the second diameter being smaller the first diameter, and is capable of being positioned at a targeted position within a lumen transluminally when the stent is in its compressed state, and a covering sleeve of a collagen material, the support framework and the covering sleeve being substantially the same length and substantially overlapping, and wherein the sleeve of collagen material is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 2
Dependent Claim
126 words
In combination, a vascular prostheses comprised of an expandable support framework, the expandable support framework comprising a stent, which has an expanded state having a first diameter and a compressed state having a second diameter, the second diameter being smaller the first diameter, and is capable of being positioned at a targeted position within a lumen transluminally when the stent is in its compressed state, and a covering sleeve of a collagen material, the support framework and the covering sleeve being substantially the same length and substantially overlapping, and wherein the sleeve of collagen material is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 3
Dependent Claim
15 words
The combination of claim 1 wherein the collagen material covers the stent inside and out.
Claim 4
Dependent Claim
20 words
The combination of claim 2 wherein the collagen is in the form of an outer sleeve and an inner sleeve.
Claim 5
Dependent Claim
15 words
The combination of claim 1 wherein the collagen material is comprised of collagen per se.
Claim 6
Dependent Claim
16 words
The combination of claim 1 wherein the collagen material is comprised of collagen on a support.
Claim 7
Dependent Claim
11 words
The combination of claim 5 wherein the support is a fabric.
Claim 8
Dependent Claim
14 words
The combination of claim 1 wherein the framework is a stent of variable diameter.
Claim 9
Dependent Claim
13 words
The combination of claim 7 wherein the stent is of the self-expanding type.
Claim 10
Dependent Claim
11 words
The combination of claim 1 wherein the sleeve has elastic properties.
Claim 11
Dependent Claim
20 words
The combination of claim 1 wherein the sleeve is sized large with respect to the framework at least before implantation.
Claim 12
Dependent Claim
11 words
The combination of claim 1 wherein the collagen includes added agent.
Claim 13
Dependent Claim
10 words
The combination of claim 11 wherein the agent is heparin.
Claim 14
Dependent Claim
23 words
The combination of claim 1 including a multi-layer arrangement of Type I and Type IV collagen material on the outside of the stent.
Claim 15
Dependent Claim
13 words
The combination of claim 13 wherein the Type IV is the outermost layer.
Claim 16
Dependent Claim
11 words
The combination of claim 14 wherein the Type IV is SIS.
Claim 17
Dependent Claim
102 words
In combination, a vascular expandable stent and a layer of collagen material in the form of a sleeve overlying the stent, the layer of collagen material being substantially the same length and substantially overlapping the stent so that when the combination is inserted within a vascular lumen, the layer of collagen material is positioned between the stent and the vascular wall of the lumen, and wherein the sleeve of collagen material is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 18
Dependent Claim
102 words
In combination, a vascular expandable stent and a layer of collagen material in the form of a sleeve overlying the stent, the layer of collagen material being substantially the same length and substantially overlapping the stent so that when the combination is inserted within a vascular lumen, the layer of collagen material is positioned between the stent and the vascular wall of the lumen, and wherein the sleeve of collagen material is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 19
Dependent Claim
104 words
In combination, a vascular prostheses comprised of a generally cylindrical expandable support stent, which has an expanded state having a first diameter and a compressed state having a second diameter, the second diameter being smaller than the first diameter, and is capable of being positioned at a targeted position within a lumen transluminally when the stent is in its compressed state, and an inner luminal liner comprising collagen material, wherein the collagen liner is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 20
Dependent Claim
104 words
In combination, a vascular prostheses comprised of a generally cylindrical expandable support stent, which has an expanded state having a first diameter and a compressed state having a second diameter, the second diameter being smaller than the first diameter, and is capable of being positioned at a targeted position within a lumen transluminally when the stent is in its compressed state, and an inner luminal liner comprising collagen material, wherein the collagen liner is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 21
Dependent Claim
13 words
The combination of claim 17 wherein the collagen material comprises a bilayer arrangement.
Claim 22
Dependent Claim
17 words
The combination of claim 18 wherein one of the layers in the bilayer is a polymeric material.
Claim 23
Dependent Claim
18 words
The combination of claim 19 wherein the bilayer liner is comprised at least two types of collagen material.
Claim 24
Dependent Claim
16 words
The combination of claim 20 wherein the collagen material includes Type I and Type IV layers.
Claim 25
Dependent Claim
11 words
The combination of claim 21 wherein the Type IV is SIS.
Claim 26
Dependent Claim
21 words
The combination of claim 22 wherein the Type IV is the innermost layer and the Type I layer includes a drug.
Claim 27
Dependent Claim
12 words
The combination of claim 17 wherein the stent is of variable diameter.
Claim 28
Dependent Claim
13 words
The combination of claim 24 wherein the stent is of the self-expanding type.
Claim 29
Dependent Claim
20 words
The combination of claim 17 wherein the liner has cuffs at either end which overlap the ends of the stent.
Claim 30
Dependent Claim
12 words
The combination of claim 17 wherein the collagen includes an added agent.
Claim 31
Dependent Claim
10 words
The combination of claim 27 wherein the agent is heparin.
Claim 32
Dependent Claim
16 words
The combination of claim 17 wherein the stent has wall openings and the liner is perforated.
Claim 33
Dependent Claim
14 words
The combination of claim 29 wherein the perforations are about 10-60 microns in diameter.
Claim 34
Dependent Claim
15 words
The combination of claim 17 including SIS collagen material on the outside of the stent.
Claim 35
Dependent Claim
111 words
In combination, a vascular prosthesis comprised of an expandable stent, which has an expanded state having a first diameter and a compressed state having a second diameter, the second diameter being smaller than the first diameter, and is capable of being positioned at a targeted position within a lumen transluminally when the stent is in its compressed state, and inner and outer layer of SIS collagen material positioned on the stent, wherein at least one of the layers of collagen is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 36
Dependent Claim
111 words
In combination, a vascular prosthesis comprised of an expandable stent, which has an expanded state having a first diameter and a compressed state having a second diameter, the second diameter being smaller than the first diameter, and is capable of being positioned at a targeted position within a lumen transluminally when the stent is in its compressed state, and inner and outer layer of SIS collagen material positioned on the stent, wherein at least one of the layers of collagen is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 37
Dependent Claim
97 words
In combination, a vascular prosthesis comprised of an expandable stent, which is expandable from a first cylindrical position to a second cylindrical position and is capable of being positioned at a targeted position within a lumen transluminally when the stent is in its compressed state, a collagen coating on the stent and a collagen sleeve on the outside of the stent, wherein the sleeve of collagen is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 38
Dependent Claim
97 words
In combination, a vascular prosthesis comprised of an expandable stent, which is expandable from a first cylindrical position to a second cylindrical position and is capable of being positioned at a targeted position within a lumen transluminally when the stent is in its compressed state, a collagen coating on the stent and a collagen sleeve on the outside of the stent, wherein the sleeve of collagen is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 39
Dependent Claim
19 words
The combination of claim 33 wherein the sleeve is SIS and the coating is Type I or Type IV.
Claim 40
Dependent Claim
94 words
An expandable stent, which is expandable from a first cylindrical position to a second cylindrical position and is capable of being positioned at a targeted position within a lumen transluminally when the stent is in its compressed state, comprised of a generally cylindrical body coated with a collagen material and carrying an overlying sleeve of collagen material, wherein the sleeve of collagen material is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 41
Dependent Claim
94 words
An expandable stent, which is expandable from a first cylindrical position to a second cylindrical position and is capable of being positioned at a targeted position within a lumen transluminally when the stent is in its compressed state, comprised of a generally cylindrical body coated with a collagen material and carrying an overlying sleeve of collagen material, wherein the sleeve of collagen material is in sheet form and is oriented with respect to the longitudinal dimension of the stent such that the stretch properties of the collagen are on a bias with respect thereto.
Claim 42
Dependent Claim
21 words
The stent of claim 35 wherein the collagen coating is selected from the group consisting of Type IV and Type I.
Claim 43
Dependent Claim
14 words
The stent of claim 36 wherein the collagen sleeve is comprised of Type IV.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-12-01 | 2001-06-02 | 2001-12-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-12-01 | 2005-06-02 | 2005-12-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-12-01 | 2009-06-02 | 2009-12-02 | $7700.00 | Window Closed / Lapsed |