US4956178A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Tissue graft composition
Assignee: Purdue Research Foundation
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Filing: 1989-11-06
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Granted: 1990-09-11
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Expires: 2009-11-06
Abstract
Abstract This invention relates to a method for preparation of a tissue graft composition from a segment of small intestine. A tissue graft composition is described which comprises the tunica submucosa of a segment of small intestine of a warm-blooded vertebrate wherein the tunica submucosa is deliminated from the tunica muscularis and at least the luminal portion of the tunica mucosa. The tissue graft composition has been shown to have excellent mechanical characteristics, as well as non-allergenicity and non-thrombogenicity in applications as vascular autografts, vascular allografts, and vascular heterografts.
Inventors
- 👤 Stephen F. Badylak
- 👤 Leslie A. Geddes
- 👤 Gary Lantz
- 👤 Arthur C. Coffey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:46
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3604; A61L27/3629; A61L27/50; A61L27/507
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
57 words
A tissue graft composition comprising the tunica submucosa, the muscularis mucosa and the stratum compactum of the tunica mucosa of a segment of intestinal tissue of a warm-blooded vertebrate, said tunica submucosa, muscularis mucosa and stratum compactum being delaminated from the tunica muscularis and the luminal portion of the tunica mucosa of said segment of intestinal tissue.
Claim 2
Dependent Claim
57 words
A tissue graft composition comprising the tunica submucosa, the muscularis mucosa and the stratum compactum of the tunica mucosa of a segment of intestinal tissue of a warm-blooded vertebrate, said tunica submucosa, muscularis mucosa and stratum compactum being delaminated from the tunica muscularis and the luminal portion of the tunica mucosa of said segment of intestinal tissue.
Claim 3
Dependent Claim
24 words
The tissue graft composition of claim 1 formed into a cylinder having a pre-determined luminal diameter and sutured along the length of the cylinder.
Claim 4
Dependent Claim
18 words
The tissue graft composition of claim 2 wherein the stratum compactum forms the luminal surface of the cylinder.
References Cited (Backward Citations)
US3562820A
Cited
US4502159A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-09-10 | 1994-03-12 | 1994-09-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-09-10 | 1998-03-12 | 1998-09-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-09-10 | 2002-03-12 | 2002-09-11 | $7700.00 | Window Closed / Lapsed |