US4378017A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Composite material of de-N-acetylated chitin and fibrous collagen
Assignee: KUREJA KAGAKU KOGYO KK
•
Filing: 1981-03-11
•
Granted: 1983-03-29
•
Expires: 2001-03-11
Abstract
Abstract A composite material of de-N-acetylated chitin and fibrous collagen, which may be prepared by bringing the de-N-acetylated chitin and the fibrous collagen into mutual contact in an aqueous acidic medium followed by deacidifying the obtained product, the fibrous collagen being able to be partially replaced by gelatin and/or soluble collagen, and a shaped material derived from the composite material is excellent in mechanical strength, heat-resistance and biostability and advantageously employed in the field of medical materials, edibles such as edible casing and base materials for inmobilizing enzyme.
Inventors
- 👤 Junichi Kosugi
- 👤 Tadaaki Kato
- 👤 Masayuki Funabashi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 22:30
CPC Classifications
C; C12; C12N; C12N11/00; C12N11/02; C12N11/10; A; A22; A22C; A22C13/00; A22C13/0013; A22C13/0016; A61; A61L; A61L27/00; A61L27/14; A61L27/20; A61L27/26; A61L33/00; A61L33/0005; A61L33/0011; C08; C08L; C08L5/00; C08L5/08; Y; Y10; Y10S; Y10S128/00; Y10S128/08; Y10S128/22; Y10S623/00; Y10S623/915; Y10S623/916; Y10S623/917; Y10T; Y10T428/00; Y10T428/29; Y10T428/2913; Y10T428/2933; Y10T428/2964
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
12 words
Composite thrombogenic, physiological saline solution-insoluble material of de-N-acetylated chitin and fibrous collagen.
Claim 2
Dependent Claim
12 words
Composite thrombogenic, physiological saline solution-insoluble material of de-N-acetylated chitin and fibrous collagen.
Claim 3
Dependent Claim
17 words
Composite material of claim 1, wherein the fibrous collagen is partially replaced by gelatin and/or soluble collagen.
Claim 4
Dependent Claim
16 words
Composite material of claim 1 or 2, wherein the fibrous collagen is previously cross-linked or acylated.
Claim 5
Dependent Claim
14 words
Composite material of any one of claims 1 to 3, which is further cross-linked.
Claim 6
Dependent Claim
14 words
Edible material comprising the composite material of any one of claims 1 to 4.
Claim 7
Dependent Claim
14 words
Medical material comprising the composite material of any one of claims 1 to 4.
Claim 8
Dependent Claim
17 words
Base material for immobilizing enzyme, comprising the composite material of any one of claims 1 to 4.
Claim 9
Dependent Claim
29 words
A method for preparing a composite material of claim 1, comprising bringing de-N-acetylated chitin into contact with fibrous collagen in an acidic medium followed by deacidifying the obtained product.
Claim 10
Dependent Claim
35 words
A method of claim 8, wherein the contact of the de-N-acetylated chitin with the fibrous collagen is effected by mixing an aqueous acidic solution of the de-N-acetylated chitin and an aqueous dispersion of fibrous collagen.
Claim 11
Dependent Claim
37 words
A method of claim 8, wherein the contact of the de-N-acetylated chitin with the fibrous collagen is effected by immersing a previously shaped material of the fibrous collagen into an aqueous acidic solution of the de-N-acetylated chitin.
Claim 12
Independent Claim
22 words
A method of any one of claims 8 to 10, wherein the fibrous collagen is partially replaced by gelatin and/or soluble collagen.
Claim 13
Dependent Claim
21 words
A method of claim 8, wherein the fibrous collagen is previously cross-linked or acylated before the contact with the de-N-acetylated chitin.
Claim 14
Dependent Claim
55 words
A method of claim 8, wherein the deacidifying is effected by the addition of an aqueous alkaline solution to said obtained product, by the removal of the acid in said acidic medium by evaporation, or by the electrodeposition of said obtained product wherein said acid is neutralized by OH - ions formed by said electrodeposition.
Claim 15
Dependent Claim
13 words
A method of claim 8, wherein the resultant composite material is further cross-linked.
References Cited (Backward Citations)
US3523027A
Cited
US3833744A
Cited
GB1515963A
Cited
US4280954A
Cited
US4264155A
Cited
US4260228A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-03-28 | 1986-09-27 | 1987-03-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-03-28 | 1990-09-27 | 1991-03-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-03-28 | 1994-09-27 | 1995-03-29 | $7700.00 | Window Closed / Lapsed |