US5026381A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Multi-layered, semi-permeable conduit for nerve regeneration comprised of type 1 collagen, its method of manufacture and a method of nerve regeneration using said conduit
Assignee: Colla-Tec Inc
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Filing: 1990-08-01
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Granted: 1991-06-25
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Expires: 2010-08-01
Abstract
Abstract The present invention is directed to hollow conduits whose walls are comprised of Type I collagen and are characterized by having a multi-layered, semi-permeable structure, which conduits are used to promote nerve regeneration across a gap of a severed nerve. Methods of making the nerve regeneration conduit are also disclosed.
Inventors
- 👤 Shu-Tung Li
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 22:31
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/11; A61B17/1128; A61L; A61L31/00; A61L31/04; A61L31/043; A61L31/044; A61L31/14; A61L31/146; A61B2017/00004; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2002/30001; A61F2002/30108; A61F2002/30199; A61F2002/30224; A61F2002/30235; A61F2230/00; A61F2230/0063; A61F2230/0069; A61L2430/00; A61L2430/32
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
93 words
A method of promoting in vivo regeneration of a mammalian severed nerve so as to bridge a gap between its severed ends comprising bringing the respective ends of the severed nerve into contact with each end of a hollow conduit whose walls are comprised of Type I collagen, said walls characterized by having an inner layer communicating with the hollow interior of the conduit having a pore size in the range of from about 0.006 μm to about 5.0 μm and a substantially porous outer layer communicating with the exterior of the conduit.
Claim 2
Independent Claim
93 words
A method of promoting in vivo regeneration of a mammalian severed nerve so as to bridge a gap between its severed ends comprising bringing the respective ends of the severed nerve into contact with each end of a hollow conduit whose walls are comprised of Type I collagen, said walls characterized by having an inner layer communicating with the hollow interior of the conduit having a pore size in the range of from about 0.006 μm to about 5.0 μm and a substantially porous outer layer communicating with the exterior of the conduit.
Claim 3
Dependent Claim
21 words
The method of claim 1, wherein the ends of the severed nerve are sutured to each respective end of the conduit.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-06-24 | 1994-12-24 | 1995-06-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-06-24 | 1998-12-24 | 1999-06-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-06-24 | 2002-12-24 | 2003-06-25 | $7700.00 | Window Closed / Lapsed |