Patent US6402784B1 successfully refreshed from Google Patents.
US6572650B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bioengineered vascular graft support prostheses
Assignee: Organogenesis Inc
•
Filing: 1999-06-04
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Granted: 2003-06-03
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Expires: 2019-06-04
Abstract
Abstract The invention is directed to bioengineered vascular graft support prostheses prepared from cleaned tissue material derived from animal sources. The bioengineered graft prostheses of the invention are prepared using methods that preserve cell compatibility, strength, and bioremodelability of the processed tissue matrix. The bioengineered graft prostheses are used for implantation, repair, or for use in a mammalian host.
Inventors
- 👤 Ginger A. Abraham
- 👤 Robert M. Carr, Jr.
- 👤 Tam Huynh
- 👤 Otto Per Hagen
- 👤 Mark Davies
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:06
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/507; A61L27/14; A61L27/22; A61L27/24; A61L27/36; A61L27/3604; A61L27/3629; A61L27/40; B; B29; B29C; B29C53/00; B29C53/36; B29C53/38; B29C53/40; B29C53/56; B29C53/562
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
88 words
A method for producing a collagen tube comprising at least one layer of submucosal collagen of small intestine wherein the method comprises: (a) rolling the submucosal collagen around a mandrel and over itself one complete revolution to form a two layer submucosal collagen tube; (b) drying the tube on the mandrel; (c) contacting the tube with a crosslinking agent to crosslink the collagen; (d) removing the crosslinking agent by rinsing the tube; (e) drying the crosslinked tube on the mandrel; and, (f) removing the tube from the mandrel.
Claim 2
Independent Claim
88 words
A method for producing a collagen tube comprising at least one layer of submucosal collagen of small intestine wherein the method comprises: (a) rolling the submucosal collagen around a mandrel and over itself one complete revolution to form a two layer submucosal collagen tube; (b) drying the tube on the mandrel; (c) contacting the tube with a crosslinking agent to crosslink the collagen; (d) removing the crosslinking agent by rinsing the tube; (e) drying the crosslinked tube on the mandrel; and, (f) removing the tube from the mandrel.
Claim 3
Dependent Claim
23 words
The method of claim 1 further comprising the step (g) contacting the collagen tube with a peracetic acid to sterilize the collagen tube.
Claim 4
Independent Claim
88 words
A method of using a bioremodelable prosthesis comprising a collagen tube comprising at least one layer of processed tissue matrix of crosslinked submucosal collagen to prevent stretch injury in an autologous vein graft having two ends implanted in the arterial circulation comprising: (a) removing a segment of vasculature; (b) anastomosizing a first end of the vein graft; (c) passing the vein graft through a collagen tube; (d) anastomosizing a second end of the vein graft; and, (e) covering the vein graft and both anastomoses with said collagen tube.
Claim 5
Independent Claim
88 words
A method of using a bioremodelable prosthesis comprising a collagen tube comprising at least one layer of processed tissue matrix of crosslinked submucosal collagen to prevent stretch injury in an autologous vein graft having two ends implanted in the arterial circulation comprising: (a) removing a segment of vasculature; (b) anastomosizing a first end of the vein graft; (c) passing the vein graft through a collagen tube; (d) anastomosizing a second end of the vein graft; and, (e) covering the vein graft and both anastomoses with said collagen tube.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2006-06-02 | 2006-12-02 | 2007-06-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2010-06-02 | 2010-12-02 | 2011-06-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2014-06-02 | 2014-12-02 | 2015-06-03 | $7700.00 | Window Closed / Lapsed |