US5520664A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Catheter having a long-lasting antimicrobial surface treatment
Assignee: Spire Corp
•
Filing: 1994-01-11
•
Granted: 1996-05-28
•
Expires: 2014-01-11
Abstract
Abstract Catheters including at least one component having a tissue interfacing surface characterized by a substantially nonleaching surface treatment of antimicrobial metal. The component can be a subcutaneous cuff, and the antimicrobial metal can be silver. The process for implanting the silver atoms can include dry coating the tissue interfacing surface of the catheter by way of ion beam assisted deposition. Alternatively, the silver can be introduced into the tissue interfacing surface by ion implantation.
Inventors
- 👤 Raymond J. Bricault, Jr.
- 👤 John E. Barry
- 👤 Piran Sioshansi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 17:28
CPC Classifications
A; A61; A61L; A61L29/00; A61L29/14; A61L29/16; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/30767; A61L27/00; A61L27/50; A61L27/54; A61L29/08; A61L29/10; A61L31/00; A61L31/08; A61L31/082; A61L31/14; A61L31/16; C; C23; C23C; C23C14/00; C23C14/06; C23C14/14; C23C14/20; C23C14/22; C23C14/50; C23C14/505; C23C14/56; C23C14/564; C23C14/566; A61B; A61B17/00; A61B17/56; A61B17/58; A61B17/60; A61B17/68; A61B17/72; A61F2/20; A61F2/3094; A61F2/82; A61F2002/30001; A61F2002/30667; A61F2002/30677; A61L2300/00; A61L2300/10; A61L2300/102; A61L2300/104; A61L2300/40; A61L2300/404; A61L2300/60; A61L2300/606; A61L2300/62; A61L2300/622; A61L2400/00; A61L2400/18; A61M; A61M25/00; A61M25/0043; A61M2025/0056; A61M25/0017
Claims Analysis
Total Claims: 39
Claim 1
Independent Claim
49 words
A catheter formed from a polymeric material and having an outer surface, the surface having embedded by ion beam assisted deposition therein atoms of an antimicrobial metal, the atoms extending in a subsurface stratum to a predetermined depth from the outer surface to form a substantially nonleaching surface treatment.
Claim 2
Dependent Claim
49 words
A catheter formed from a polymeric material and having an outer surface, the surface having embedded by ion beam assisted deposition therein atoms of an antimicrobial metal, the atoms extending in a subsurface stratum to a predetermined depth from the outer surface to form a substantially nonleaching surface treatment.
Claim 3
Dependent Claim
29 words
The catheter of claim 1 wherein the antimicrobial metal comprises at least one of silver, chromium, aluminum, nickel, tungsten, molybdenum, platinum, iridium, gold, silver, mercury, copper zinc and cadmium.
Claim 4
Dependent Claim
35 words
The catheter of claim 1 wherein the atoms of the antimicrobial metal are embedded to a depth of less than about 5 microns to ensure that the atoms of the antimicrobial metal are substantially nonleaching.
Claim 5
Dependent Claim
22 words
The catheter of claim 1 further comprising a uniform coating of the antimicrobial metal formed on the outer surface of the material.
Claim 6
Dependent Claim
37 words
The catheter of claim 1 wherein the outer surface has disposed between it and the atoms of the antimicrobial metal, atoms of an adhesion-promoting material which enhance the binding of the antimicrobial metal to the outer surface.
Claim 7
Dependent Claim
11 words
The catheter of claim 5 wherein the adhesion-promoting material comprises titanium.
Claim 8
Dependent Claim
55 words
The catheter of claim 5 wherein the adhesion-promoting material has disposed between it and the atoms of the antimicrobial metal, atoms of a barrier-forming material which form at least one of a barrier to degradation or diffusion of the adhesion-promoting atoms and an impediment to galvanic interaction between the antimicrobial metal and the adhesion-promoting material.
Claim 9
Dependent Claim
11 words
The catheter of claim 7 wherein the barrier-forming material comprises palladium.
Claim 10
Dependent Claim
59 words
The catheter of claim 1 wherein the outer surface has disposed between it and the atoms of the antimicrobial metal, atoms of titanium and palladium wherein the titanium atoms are predominantly located adjacent to the surface and interposed between the surface and the antimicrobial metal, and palladium atoms are predominantly interposed between the titanium atoms and the antimicrobial metal.
Claim 11
Dependent Claim
15 words
The catheter of claim 1 wherein the outer surface is a subcutaneous catheter cuff surface.
Claim 12
Dependent Claim
17 words
The catheter of claim 10 wherein the subcutaneous catheter cuff is formed from a porous polymeric material.
Claim 13
Dependent Claim
14 words
The catheter of claim 10 wherein the cuff is formed from a polymeric material.
Claim 14
Dependent Claim
54 words
The catheter of claim 11 wherein the surface has tissue interfacing fibers that form a fabric geometry having interstitial spaces between the fibers, and wherein the embedded atoms of the antimicrobial metal are embedded in the fibers, without filling the interstitial spaces in the fabric geometry, thus preserving the porosity of the subcutaneous cuff.
Claim 15
Dependent Claim
18 words
The catheter of claim 10 wherein the material comprises at least one of polyesters, fluropolymers, polyurethanes and silicones.
Claim 16
Dependent Claim
89 words
A subcutaneous cuff formed from a porous polymeric material and having fibers that form a fabric geometry having interstitial spaces between the fibers, each of the fibers having an outer surface the outer surfaces having embedded by ion beam assisted deposition therein atoms of an antimicrobial metal, the atoms extending in a subsurface stratum to a predetermined depth from the outer surface of each fiber to form a substantially nonleaching surface treatment, and the interstitial spaces between the fibers being unchanged by the embedded atoms of the antimicrobial metal.
Claim 17
Dependent Claim
89 words
A subcutaneous cuff formed from a porous polymeric material and having fibers that form a fabric geometry having interstitial spaces between the fibers, each of the fibers having an outer surface the outer surfaces having embedded by ion beam assisted deposition therein atoms of an antimicrobial metal, the atoms extending in a subsurface stratum to a predetermined depth from the outer surface of each fiber to form a substantially nonleaching surface treatment, and the interstitial spaces between the fibers being unchanged by the embedded atoms of the antimicrobial metal.
Claim 18
Dependent Claim
30 words
The subcutaneous cuff of claim 15 wherein the antimicrobial metal comprises at least one of silver, chromium, aluminum, nickel, tungsten, molybdenum, platinum, iridium, gold, silver, mercury, copper, zinc and cadmium.
Claim 19
Dependent Claim
44 words
The subcutaneous cuff of claim 15 wherein the atoms of the antimicrobial metal are embedded into the outer surfaces of the tissue interfacing fibers to a depth of between about 0.01 microns and 5 microns to ensure that the antimicrobial metal is substantially nonleaching.
Claim 20
Dependent Claim
23 words
The subcutaneous cuff of claim 15 further comprising coating of the antimicrobial metal formed on the outer surfaces of the tissue interfacing fibers.
Claim 21
Dependent Claim
38 words
The subcutaneous cuff of claim 15 wherein the outer surfaces have disposed between them and the atoms of the antimicrobial metal, atoms of an adhesion-promoting material which enhance the binding of the antimicrobial metal to the outer surfaces.
Claim 22
Dependent Claim
12 words
The subcutaneous cuff of claim 19 wherein the adhesion-promoting atoms comprise titanium.
Claim 23
Dependent Claim
56 words
The subcutaneous cuff of claim 19 wherein the adhesion-promoting material has disposed between it and the atoms of the antimicrobial metal, atoms of a barrier-forming material which form at least one of a barrier to degradation or diffusion of the adhesion-promoting atoms and an impediment to galvanic interaction between the antimicrobial metal and the adhesion-promoting atoms.
Claim 24
Dependent Claim
12 words
The subcutaneous cuff of claim 21 wherein the barrier-forming atoms comprise palladium.
Claim 25
Dependent Claim
61 words
The subcutaneous cuff of claim 15 wherein the outer surfaces have disposed between them and the atoms of the antimicrobial metal, atoms of titanium and palladium wherein the titanium atoms are predominantly located adjacent to the surface and interposed between the surface and the antimicrobial metal, and the palladium atoms are predominantly interposed between the titanium atoms and the antimicrobial metal.
Claim 26
Dependent Claim
20 words
The subcutaneous cuff of claim 14 wherein the polymeric material comprises at least one of polyesters, fluropolymers, polyurethanes, and silicones.
Claim 27
Dependent Claim
35 words
The subcutaneous cuff of claim 14 wherein the atoms of the antimicrobial metal are embedded in the surfaces of fibers, which extend into the fabric geometry to a depth of greater than about 5 microns.
Claim 28
Dependent Claim
44 words
The subcutaneous cuff of claim 14 wherein the outer surfaces have disposed between them and the atoms of the antimicrobial metal, atoms of an adhesion-promoting material which enhance the binding of the antimicrobial metal to the outer surfaces, without filling in the interstitial spaces.
Claim 29
Dependent Claim
65 words
The subcutaneous cuff of claim 26 wherein the coating of the adhesion-promoting material has disposed between it and the atoms of the antimicrobial metal, atoms of a barrier-forming material which form at least one of a barrier to degradation or diffusion of the adhesion promoting atoms and an impediment to galvanic interaction between the antimicrobial metal and the adhesion-promoting atoms without filling the interstitial spaces.
Claim 30
Dependent Claim
114 words
A subcutaneous cuff formed from a porous polymeric material and having tissue interfacing fibers that form a fabric geometry having interstitial spaces between the fibers, each of the fibers having an outer surface, the outer surfaces having embedded therein atoms of an adhesion-promoting material and formed thereon a coating of the adhesion-promoting material, the coating of the adhesion-promoting material having embedded therein atoms of a barrier-promoting material and formed thereon a coating of the barrier-promoting material, the barrier-promoting material having atoms of silver metal embedded therein, wherein the adhesion-promoting material enhances the bonding of the silver to the outer surfaces, and the barrier material reduces galvanic interaction between the silver and the adhesion-promoting material.
Claim 31
Dependent Claim
114 words
A subcutaneous cuff formed from a porous polymeric material and having tissue interfacing fibers that form a fabric geometry having interstitial spaces between the fibers, each of the fibers having an outer surface, the outer surfaces having embedded therein atoms of an adhesion-promoting material and formed thereon a coating of the adhesion-promoting material, the coating of the adhesion-promoting material having embedded therein atoms of a barrier-promoting material and formed thereon a coating of the barrier-promoting material, the barrier-promoting material having atoms of silver metal embedded therein, wherein the adhesion-promoting material enhances the bonding of the silver to the outer surfaces, and the barrier material reduces galvanic interaction between the silver and the adhesion-promoting material.
Claim 32
Dependent Claim
54 words
A subcutaneous cuff for interfacing with subcutaneous tissue formed from a porous polymeric material and having an outer surface, having embedded by ion beam assisted deposition therein atoms of an antimicrobial metal, the atoms extending in a subsurface stratum to a predetermined depth from the outer surface to form a substantially nonleaching surface treatment.
Claim 33
Dependent Claim
54 words
A subcutaneous cuff for interfacing with subcutaneous tissue formed from a porous polymeric material and having an outer surface, having embedded by ion beam assisted deposition therein atoms of an antimicrobial metal, the atoms extending in a subsurface stratum to a predetermined depth from the outer surface to form a substantially nonleaching surface treatment.
Claim 34
Dependent Claim
43 words
The cuff of claim 29 wherein the outer surface has disposed between it and the atoms of the antimicrobial metal, atoms of an adhesion-promoting material, wherein the atoms of the adhesion-promoting material enhance the binding of the antimicrobial metal to the outer surface.
Claim 35
Dependent Claim
65 words
The cuff of claim 30 wherein the atoms of the adhesion-promoting material has disposed between it and the atoms of the antimicrobial metal, atoms of a barrier-forming material, wherein the atoms of the barrier-forming material form at least one of a barrier to degradation or diffusion of the adhesion-promoting atoms and an impediment to galvanic interaction between the antimicrobial metal atoms and the adhesion-promoting atoms.
Claim 36
Dependent Claim
11 words
The cuff of claim 31 wherein the barrier-forming material comprises palladium.
Claim 37
Dependent Claim
31 words
The cuff of claim 29 wherein the antimicrobial metal comprises at least one of silver, chromium, zirconium, aluminum, nickel, tungsten, molybdenum, tantalum, platinum, iridium, gold, silver, mercury, copper, zinc and cadmium.
Claim 38
Dependent Claim
11 words
The cuff of claim 30 wherein the adhesion-promoting material comprises titanium.
Claim 39
Dependent Claim
19 words
The cuff of claim 29 wherein the polymeric material comprises at least one of polyesters, fluropolymers, silicones, and polyurethanes.
References Cited (Backward Citations)
US3589975A
Cited
US3557795A
Cited
US3695921A
Cited
US3699956A
Cited
US4039699A
Cited
US4152478A
Cited
US4027393A
Cited
US4054139A
Cited
US4281029A
Cited
US4479795A
Cited
US4253463A
Cited
EP0029787B1
Cited
US4388164A
Cited
US4452827A
Cited
US4476590A
Cited
US4411648A
Cited
US4443488A
Cited
US4374717A
Cited
DE3228849A1
Cited
US4440108A
Cited
DE3302567A1
Cited
US4592920A
Cited
US4683149A
Cited
US4581028A
Cited
US4994060A
Cited
US4886505A
Cited
EP0206024A2
Cited
US5057106A
Cited
US4693760A
Cited
US4871366A
Cited
US4846834A
Cited
US4718905A
Cited
EP0257923A2
Cited
US4743493A
Cited
US4743308A
Cited
US4923450A
Cited
US4872922A
Cited
US4855026A
Cited
DE3830359A1
Cited
US5069227A
Cited
US5165952A
Cited
US4936281A
Cited
US5049140A
Cited
US5067491A
Cited
US5152273A
Cited
WO1992011043A1
Cited
US5223309A
Cited
US5308704A
Cited
WO1993007924A1
Cited
US5236509A
Cited
WO1993016212A1
Cited
WO1993023092A1
Cited
DE4328999A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-05-28 | 1999-11-27 | 2000-05-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-05-28 | 2003-11-27 | 2004-05-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-05-28 | 2007-11-27 | 2008-05-28 | $7700.00 | Window Closed / Lapsed |