US6589266B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
Thrombosis filter having a surface treatment
Assignee: Boston Scientific Scimed Inc
•
Filing: 2001-07-18
•
Granted: 2003-07-08
•
Expires: 2021-07-18
Abstract
Abstract A thrombosis filter configured for placement within a blood vessel lumen. The thrombosis filter of the present invention includes a body element, a plurality of struts, and a surface treatment. The surface treatment, comprised in part of an anti-proliferative or anti-angiogenic drug, is applied to portions of the thrombosis filter in order to regulate neointimal growth around the thrombosis filter and its anchor elements. The thrombosis filter may further contain a first and a second surface treatment layer. The first surface treatment layer possesses endothelial cell growth enhancing properties, while the second surface treatment layer includes the anti-proliferative or anti-angiogenic drug. The surface treatment may alternatively be applied to a substrate, which in turn is applied to the filter.
Inventors
- 👤 Forrest D. Whitcher
- 👤 Alan Kaganov
- 👤 Sally C. Thornton
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:24
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/01; A61F2/0105; A61F2002/016; A61F2230/00; A61F2230/0002; A61F2230/0028; A61F2230/005; A61F2230/0063; A61F2230/0067; A61F2230/0073; A61F2230/0078; A61F2230/008; A61F2250/00; A61F2250/0058; A61F2250/0067
Claims Analysis
Total Claims: 32
Claim 1
Independent Claim
141 words
A thrombosis filter element for placement within a blood vessel lumen defined by a blood vessel wall, comprising: a first body element; a first strut having a joining end coupled to the first body element, and a free end adapted to engage the blood vessel wall; a second body element coupled to the first body element; a second strut having a joining end coupled to the second body element, and a free end adapted to engage the blood vessel wall; and a surface treatment covering at least a portion of the thrombosis filter element, wherein the surface treatment comprises two layers, a first surface treatment layer located between a second surface treatment layer and the thrombosis filter, the first surface treatment layer having properties which enhance endothelial cell growth, and the second surface treatment layer including an anti-proliferative or anti-angiogenic drug.
Claim 2
Dependent Claim
141 words
A thrombosis filter element for placement within a blood vessel lumen defined by a blood vessel wall, comprising: a first body element; a first strut having a joining end coupled to the first body element, and a free end adapted to engage the blood vessel wall; a second body element coupled to the first body element; a second strut having a joining end coupled to the second body element, and a free end adapted to engage the blood vessel wall; and a surface treatment covering at least a portion of the thrombosis filter element, wherein the surface treatment comprises two layers, a first surface treatment layer located between a second surface treatment layer and the thrombosis filter, the first surface treatment layer having properties which enhance endothelial cell growth, and the second surface treatment layer including an anti-proliferative or anti-angiogenic drug.
Claim 3
Dependent Claim
32 words
A thrombosis filter element according to claim 1 , wherein the first strut is comprised of materials selected from the group consisting of nitinol, stainless steel, tantalum, gold, silicone, and combinations thereof.
Claim 4
Dependent Claim
23 words
A thrombosis filter element according to claim 1 , wherein the free end of the first strut terminates in a vessel-engaging tip portion.
Claim 5
Dependent Claim
24 words
A thrombosis filter element according to claim 3 , wherein the vessel-engaging tip portion includes a sharpened portion and an adjacent flexible pad portion.
Claim 6
Dependent Claim
27 words
A thrombosis filter element according to claim 1 , wherein the joining end of the first strut is coupled to the first body element by a hub.
Claim 7
Dependent Claim
19 words
A thrombosis filter element according to claim 1 , wherein the drug includes taxol or a derivative of taxol.
Claim 8
Dependent Claim
14 words
A thrombosis filter element according to claim 1 , wherein the drug includes phosphorylcholine.
Claim 9
Dependent Claim
14 words
A thrombosis filter element according to claim 1 , wherein the drug is non-thrombogenic.
Claim 10
Dependent Claim
36 words
A thrombosis filter element according to claim 1 , wherein the second surface treatment layer is dissolvable, wherein the dissolving rate may be varied depending upon the structure and composition of the second surface treatment layer.
Claim 11
Dependent Claim
25 words
A thrombosis filter element according to claim 1 , wherein the first and second surface treatment layers cover the free end of the first strut.
Claim 12
Dependent Claim
46 words
A thrombosis filter element according to claim 1 , wherein the surface treatments, or some combination of the first surface treatment layer and the second surface treatment layer, are coated upon at least a portion of the thrombosis filter element through a dipping or spraying process.
Claim 13
Dependent Claim
136 words
A thrombosis filter element for placement within a blood vessel lumen defined by a blood vessel wall, comprising: a first body element; a first strut having a joining end coupled to the first body element, and a free end adapted to engage the blood vessel wall; wherein the free end of the first strut terminates in a vessel-engaging tip portion; wherein the vessel-engaging tip portion includes a sharpened portion and an adjacent flexible pad portion; and a surface treatment covering at least a portion of the thrombosis filter element, wherein the surface treatment comprises two layers, a first surface treatment layer located between a second surface treatment layer and the thrombosis filter, the first surface treatment layer having properties which enhance endothelial cell growth, and the second surface treatment layer including an anti-proliferative or anti-angiogenic drug.
Claim 14
Dependent Claim
136 words
A thrombosis filter element for placement within a blood vessel lumen defined by a blood vessel wall, comprising: a first body element; a first strut having a joining end coupled to the first body element, and a free end adapted to engage the blood vessel wall; wherein the free end of the first strut terminates in a vessel-engaging tip portion; wherein the vessel-engaging tip portion includes a sharpened portion and an adjacent flexible pad portion; and a surface treatment covering at least a portion of the thrombosis filter element, wherein the surface treatment comprises two layers, a first surface treatment layer located between a second surface treatment layer and the thrombosis filter, the first surface treatment layer having properties which enhance endothelial cell growth, and the second surface treatment layer including an anti-proliferative or anti-angiogenic drug.
Claim 15
Dependent Claim
54 words
A thrombosis filter element according to claim 12 , further comprising a second body element and a second strut, the second body element coupled to the first body element, and the second strut having a joining end coupled to the second body element, and a free end adapted to engage the blood vessel wall.
Claim 16
Dependent Claim
32 words
A thrombosis filter element according to claim 12 , wherein the first strut is comprised of materials selected from the group consisting of nitinol, stainless steel, tantalum, gold, silicone, and combinations thereof.
Claim 17
Dependent Claim
27 words
A thrombosis filter element according to claim 12 , wherein the joining end of the first strut is coupled to the first body element by a hub.
Claim 18
Dependent Claim
19 words
A thrombosis filter element according to claim 12 , wherein the drug includes taxol or a derivative of taxol.
Claim 19
Dependent Claim
14 words
A thrombosis filter element according to claim 12 , wherein the drug includes phosphorylcholine.
Claim 20
Dependent Claim
14 words
A thrombosis filter element according to claim 12 , wherein the drug is non-thrombogenic.
Claim 21
Dependent Claim
36 words
A thrombosis filter element according to claim 12 , wherein the second surface treatment layer is dissolvable, wherein the dissolving rate may be varied depending upon the structure and composition of the second surface treatment layer.
Claim 22
Dependent Claim
25 words
A thrombosis filter element according to claim 12 , wherein the first and second surface treatment layers cover the free end of the first strut.
Claim 23
Dependent Claim
46 words
A thrombosis filter element according to claim 12 , wherein the surface treatments, or some combination of the first surface treatment layer and the second surface treatment layer, are coated upon at least a portion of the thrombosis filter element through a dipping or spraying process.
Claim 24
Dependent Claim
117 words
A thrombosis filter element for placement within a blood vessel lumen defined by a blood vessel wall, comprising: a first body element; a first strut having a joining end coupled to the first body element, and a free end adapted to engage the blood vessel wall; a second body element coupled to the first body element; a second strut having a joining end coupled to the second body element, and a free end adapted to engage the blood vessel wall; and a surface treatment covering at least a portion of the thrombosis filter element; wherein the surface treatment is applied to a substrate comprising a pad which is disposed about the free end of the first strut.
Claim 25
Dependent Claim
117 words
A thrombosis filter element for placement within a blood vessel lumen defined by a blood vessel wall, comprising: a first body element; a first strut having a joining end coupled to the first body element, and a free end adapted to engage the blood vessel wall; a second body element coupled to the first body element; a second strut having a joining end coupled to the second body element, and a free end adapted to engage the blood vessel wall; and a surface treatment covering at least a portion of the thrombosis filter element; wherein the surface treatment is applied to a substrate comprising a pad which is disposed about the free end of the first strut.
Claim 26
Dependent Claim
24 words
A thrombosis filter according to claim 22 , wherein the pad includes a hole, and wherein the first strut is disposed in the hole.
Claim 27
Dependent Claim
117 words
A thrombosis filter element for placement within a blood vessel lumen defined by a blood vessel wall, comprising: a first body element; a first strut having a joining end coupled to the first body element, and a free end adapted to engage the blood vessel wall; a second body element coupled to the first body element; a second strut having a joining end coupled to the second body element, and a free end adapted to engage the blood vessel wall; and a surface treatment covering at least a portion of the thrombosis filter element; wherein the surface treatment is applied to a substrate comprising a tube which is disposed about the free end of the first strut.
Claim 28
Dependent Claim
117 words
A thrombosis filter element for placement within a blood vessel lumen defined by a blood vessel wall, comprising: a first body element; a first strut having a joining end coupled to the first body element, and a free end adapted to engage the blood vessel wall; a second body element coupled to the first body element; a second strut having a joining end coupled to the second body element, and a free end adapted to engage the blood vessel wall; and a surface treatment covering at least a portion of the thrombosis filter element; wherein the surface treatment is applied to a substrate comprising a tube which is disposed about the free end of the first strut.
Claim 29
Dependent Claim
24 words
A thrombosis filter according to claim 24 , wherein the tube includes a lumen, and wherein the first strut is disposed in the lumen.
Claim 30
Dependent Claim
119 words
A thrombosis filter element for placement within a blood vessel lumen defined by a blood vessel wall, comprising: a first body element; a first strut having a joining end coupled to the first body element, and a free end adapted to engage the blood vessel wall; a second body element coupled to the first body element; a second strut having a joining end coupled to the second body element, and a free end adapted to engage the blood vessel wall; and a surface treatment covering at least a portion of the thrombosis filter element; wherein the surface treatment is applied to a substrate comprising a band surrounding the first strut when the thrombosis filter is in a collapsed configuration.
Claim 31
Dependent Claim
119 words
A thrombosis filter element for placement within a blood vessel lumen defined by a blood vessel wall, comprising: a first body element; a first strut having a joining end coupled to the first body element, and a free end adapted to engage the blood vessel wall; a second body element coupled to the first body element; a second strut having a joining end coupled to the second body element, and a free end adapted to engage the blood vessel wall; and a surface treatment covering at least a portion of the thrombosis filter element; wherein the surface treatment is applied to a substrate comprising a band surrounding the first strut when the thrombosis filter is in a collapsed configuration.
Claim 32
Dependent Claim
26 words
A thrombosis filter according to claim 26 , wherein the band separates into a plurality of segments when the thrombosis filter is in an expanded configuration.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2006-07-07 | 2007-01-06 | 2007-07-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2010-07-07 | 2011-01-06 | 2011-07-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2014-07-07 | 2015-01-06 | 2015-07-08 | $7700.00 | Window Closed / Lapsed |