US5102402A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Releasable coatings on balloon catheters
Assignee: Medtronic Inc
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Filing: 1991-01-04
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Granted: 1992-04-07
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Expires: 2011-01-04
Abstract
Abstract Balloon catheters are prepared to include a coating of body affecting chemicals on the exterior of the balloon. The coating releases from the balloon when the balloon is inflated into contact with the lumen to be treated. The device provides accurate placement of the dosage required at the location in need of treatment. The coating preferably includes drugs in microcapsules or microspheres. The catheters are especially useful in balloon angioplasty procedures.
Inventors
- 👤 Michael Dror
- 👤 Paul Trescony
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 23:22
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/104; A61F; A61F2/00; A61F2/95; A61F2/958; A61L; A61L29/00; A61L29/14; A61L29/16; A61F2250/00; A61F2250/0058; A61F2250/0067; A61L2300/00; A61L2300/40; A61L2300/404; A61L2300/406; A61L2300/41; A61L2300/416; A61L2300/42; A61L2300/60; A61L2300/62; A61L2300/622; A61M2025/1043; A61M2025/105; A61M2025/1081; A61M2025/1086; A61M25/1002
Claims Analysis
Total Claims: 28
Claim 1
Independent Claim
87 words
In a balloon angioplasty catheter of the type comprising a catheter body and a balloon positioned along the length of the catheter body, said balloon including means for remotely inflating and deflating said balloon; the improvement comprising: (a) a plurality of microcapsules on the exterior of said balloon, each of said microcapsules carrying a drug or combination of drugs for treatment or diagnostics within a body lumen when said catheter is positioned and inflated therewithin such that the drug or drugs may be released from said microcapsules.
Claim 2
Dependent Claim
87 words
In a balloon angioplasty catheter of the type comprising a catheter body and a balloon positioned along the length of the catheter body, said balloon including means for remotely inflating and deflating said balloon; the improvement comprising: (a) a plurality of microcapsules on the exterior of said balloon, each of said microcapsules carrying a drug or combination of drugs for treatment or diagnostics within a body lumen when said catheter is positioned and inflated therewithin such that the drug or drugs may be released from said microcapsules.
Claim 3
Dependent Claim
32 words
The catheter of claim 1 wherein said drug or drugs are selected from the group consisting of restenosis limiting drugs, plaque deposition preventing drugs, anti-smooth muscle cell proliferation drugs and diagnostic dyes.
Claim 4
Dependent Claim
30 words
The catheter of claim 1 wherein said drug or drugs are selected from the group consisting of antiplatelet drugs, anticoagulant drugs, anti-inflammatory drugs, antimetabolite drugs and combinations of said drugs.
Claim 5
Dependent Claim
69 words
In a dilatation catheter of the type comprising a catheter body and a dilatation balloon positioned along the length of the catheter body; the improvement comprising: (a) a plurality of microcapsules on the exterior of said balloon, each of said microcapsules carrying a drug which may affect the interior of a lumen when said catheter is positioned and inflated therewithin such that said microcapsules rupture to release their contents.
Claim 6
Dependent Claim
69 words
In a dilatation catheter of the type comprising a catheter body and a dilatation balloon positioned along the length of the catheter body; the improvement comprising: (a) a plurality of microcapsules on the exterior of said balloon, each of said microcapsules carrying a drug which may affect the interior of a lumen when said catheter is positioned and inflated therewithin such that said microcapsules rupture to release their contents.
Claim 7
Dependent Claim
32 words
The catheter of claim 4 wherein said drug or drugs are selected from the group consisting of restenosis limiting drugs, plaque deposition preventing drugs, anti-smooth muscle cell proliferation drugs and diagnostic dyes.
Claim 8
Dependent Claim
29 words
The dilatation catheter of claim 4 wherein said drug is selected from the group consisting of antiplatelet drugs, anticoagulant drugs, anti-inflammatory drugs, antimetabolite drugs and combinations of said drugs.
Claim 9
Dependent Claim
18 words
The dilatation catheter of claim 4 wherein said microcapsules are attached to said balloon surface by an adhesive.
Claim 10
Dependent Claim
18 words
The dilatation catheter of claim 4 wherein said microcapsules are attached to said balloon surface by solvent welding.
Claim 11
Dependent Claim
25 words
The dilatation catheter of claim 4 wherein said microcapsules are held to said balloon within folds of said balloon formed when said balloon is deflated.
Claim 12
Dependent Claim
74 words
In a dilatation catheter of the type comprising a catheter body and a dilatation balloon positioned along the length of the catheter body; the improvement comprising: (a) a plurality of microcapsules on the exterior of said balloon, each of said microcapsules carrying a drug which may affect the interior of a lumen when said catheter is positioned and inflated therewithin such that said microcapsules will release from said balloon upon inflation of said balloon.
Claim 13
Dependent Claim
74 words
In a dilatation catheter of the type comprising a catheter body and a dilatation balloon positioned along the length of the catheter body; the improvement comprising: (a) a plurality of microcapsules on the exterior of said balloon, each of said microcapsules carrying a drug which may affect the interior of a lumen when said catheter is positioned and inflated therewithin such that said microcapsules will release from said balloon upon inflation of said balloon.
Claim 14
Dependent Claim
15 words
The dilatation balloon catheter of claim 10 wherein said microcapsules carry a plaque-affecting chemical therewithin.
Claim 15
Independent Claim
75 words
A method for limiting acute or chronic lumen closure in an animal lumen comprising the steps of: (a) inserting a dilatation catheter having a plurality of drug-containing microcapsules on the exterior of the catheter balloon into a lumen at the point where treatment is desired; (b) expanding said balloon against the walls of the lumen to break open and release the contents of the microcapsules against the lumen wall; and (c) removing said dilatation catheter.
Claim 16
Independent Claim
75 words
A method for limiting acute or chronic lumen closure in an animal lumen comprising the steps of: (a) inserting a dilatation catheter having a plurality of drug-containing microcapsules on the exterior of the catheter balloon into a lumen at the point where treatment is desired; (b) expanding said balloon against the walls of the lumen to break open and release the contents of the microcapsules against the lumen wall; and (c) removing said dilatation catheter.
Claim 17
Independent Claim
59 words
A method for forming a balloon angioplasty catheter capable of supplying drug or drugs to a body lumen, said method comprising the steps of: (a) obtaining a catheter having a balloon; such that said drug is released onto a lumen during a balloon angioplasty procedure and (b) applying a plurality of drug-containing microcapsules to the exterior of said balloon.
Claim 18
Independent Claim
59 words
A method for forming a balloon angioplasty catheter capable of supplying drug or drugs to a body lumen, said method comprising the steps of: (a) obtaining a catheter having a balloon; such that said drug is released onto a lumen during a balloon angioplasty procedure and (b) applying a plurality of drug-containing microcapsules to the exterior of said balloon.
Claim 19
Dependent Claim
21 words
The method of claim 13 wherein said step for applying microcapsules to said balloon consists of adhering microcapsules to said balloon.
Claim 20
Dependent Claim
22 words
The method of claim 13 wherein said step for applying microcapsules to said balloon consists of solvent welding microcapsules to said balloon.
Claim 21
Dependent Claim
45 words
The method of claim 13 wherein said step for applying microcapsules to said balloon consists of inflating said balloon and dusting drug-containing microcapsules onto said balloon and then deflating said balloon to trap said microcapsules in folds formed by the walls of said deflated balloon.
Claim 22
Independent Claim
74 words
A method for treating the interior of a body lumen comprising the steps of: (a) inserting a balloon catheter having a balloon having an external coating of drug containing microcapsules into a lumen to be treated and positioning said balloon of said catheter next to the lumen wall needing treatment; (b) expanding said balloon against the lumen wall to cause said microcapsules to rupture and release their contents; and (c) removing said balloon catheter.
Claim 23
Independent Claim
74 words
A method for treating the interior of a body lumen comprising the steps of: (a) inserting a balloon catheter having a balloon having an external coating of drug containing microcapsules into a lumen to be treated and positioning said balloon of said catheter next to the lumen wall needing treatment; (b) expanding said balloon against the lumen wall to cause said microcapsules to rupture and release their contents; and (c) removing said balloon catheter.
Claim 24
Dependent Claim
79 words
In a balloon angioplasty catheter of the type comprising a catheter body and a dilation balloon positioned along the length of the catheter body; the improvement comprising; (a) a releasable drug-carrying coating consisting of microcapsules in the exterior of said balloon, said drug of the type which may affect the interior of a lumen when said catheter is positioned and inflated therewithin in a balloon angioplasty procedure such that said coating is released from the balloon onto the lumen.
Claim 25
Dependent Claim
79 words
In a balloon angioplasty catheter of the type comprising a catheter body and a dilation balloon positioned along the length of the catheter body; the improvement comprising; (a) a releasable drug-carrying coating consisting of microcapsules in the exterior of said balloon, said drug of the type which may affect the interior of a lumen when said catheter is positioned and inflated therewithin in a balloon angioplasty procedure such that said coating is released from the balloon onto the lumen.
Claim 26
Dependent Claim
34 words
The dilatation catheter of claim 18 wherein said drug is selected from the group consisting of anti-smooth muscle cell proliferation drugs, antiplatelet drugs, anticoagulant drugs, anti-inflammatory drugs, anti-metabolite drugs and combinations of said drugs.
Claim 27
Dependent Claim
18 words
The dilatation catheter of claim 18 wherein said microcapsules are attached to said balloon surface by solvent welding.
Claim 28
Dependent Claim
18 words
The dilatation catheter of claim 18 wherein said microcapsules are attached to said balloon surface by an adhesive.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-04-07 | 1995-10-07 | 1996-04-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-04-07 | 1999-10-07 | 2000-04-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-04-07 | 2003-10-07 | 2004-04-07 | $7700.00 | Window Closed / Lapsed |