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WO1997033552A1 Expired / Lapsed WO ⏱️ 0.0 years remaining

Water soluble paclitaxel prodrugs

Assignee: Wallace Technologies Inc
•
Filing: 1997-03-11
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Granted: —
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Expires: 2017-03-11
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Abstract

Abstract Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble chelator, polyethylene glycol or polymer such as poly (1-glutamic acid) or poly (1-aspartic acid). Also disclosed are methods of using the compositions for treatment of tumors, autoimmune disorders such as rheumatoid arthritis and for prediction of paclitaxel uptake by tumors and radiolabeled DTPA-paclitaxel tumor imaging. Other embodiments include the coating of implantable stents for prevention of restenosis.

Inventors

  • 👤 Chun Li
  • 👤 Sidney Wallace
  • 👤 Dong-Fang Yu
  • 👤 David J. Yang

Bibliographic Details

Application Number —
Jurisdiction WO
Data Source google_patents
Last Synchronized 2026-10-23 05:18
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/337; A61K31/365; A61K47/00; A61K47/50; A61K47/51; A61K47/54; A61K47/547; A61K47/56; A61K47/59; A61K47/60; A61K47/62; A61K47/64; A61K47/645; A61K51/00; A61K51/02; A61K51/04; A61K51/0497; A61L; A61L31/00; A61L31/08; A61L31/10; A61L31/14; A61L31/16; A61P; A61P25/00; A61P35/00; A61P37/00; A61P37/02; A61P43/00; A61P9/00; A61P9/08; A61P9/10; A61K2121/00; A61K2123/00; A61L2300/00; A61L2300/40; A61L2300/416; A61L2300/60; A61L2300/606

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References Cited (Backward Citations)

US5169933A Cited
US5362831A Cited
US5489525A Cited
US5626862A Cited

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