Patent US5674287A successfully refreshed from Google Patents.
US5674287A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Biodegradable polymeric endoluminal sealing process, apparatus and polymeric product for use therein
Assignee: Endoluminal Therapeutics Inc
•
Filing: 1994-01-14
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Granted: 1997-10-07
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Expires: 2014-01-14
Abstract
Abstract A process for paving or sealing the interior surface of a tissue lumen by entering the interior tissue lument and applying a polymer to the interior surface of the tissue lumen. This is accomplished using a catheter which delivers the polymer to the tissue lument and causes it to conform to the interior surface of the lumen. The polymer can be delivered to the lumen as a monomer or prepolymer solution, or as an at least partially preformed layer on an expansible member.
Inventors
- 👤 Marvin J. Slepian
- 👤 Anton Schindler
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 10:39
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/95; A61F2/958; A61F2/02; A61F2/04; A61F2/06; A61F2/062; A61F2/82; A61F2/86; A61F2/88; A61L; A61L24/00; A61L24/001; A61L24/0015; A61L24/0031; A61L24/0042; A61L24/04; A61L24/046; A61L24/06; A61L27/00; A61L27/14; A61L27/16; A61L27/18; A61L27/28; A61L27/34; A61L27/50; A61L27/54; A61L27/58; A61L29/00; A61L29/08; A61L29/085; A61L31/00; A61L31/08; A61L31/10; A61M; A61M25/00; A61M25/0043; A61M25/10; A61M25/1011; A61M37/00; F; F16; F16B; F16B39/00; F16B39/02; F16B39/04; F16B39/06; A61F2/94; A61F2/945; A61F2/30; A61F2002/30001; A61F2002/30003; A61F2002/3006; A61F2002/30062; A61F2002/30316; A61F2002/30535; A61F2002/30581; A61F2002/30583; A61F2002/30667; A61F2002/30677; A61F2210/00; A61F2210/0004; A61F2210/0085; A61F2250/00; A61F2250/0058; A61F2250/0067; A61L2300/00; A61L2300/40; A61L2300/412; A61L2300/60; A61L2300/602; A61L2300/604; A61L2300/64; A61M25/1002; F16B37/00; F16B37/12; F16B37/122; Y; Y10; Y10S; Y10S623/00; Y10S623/92; Y10S623/921; Y10T; Y10T29/00; Y10T29/49; Y10T29/49826; Y10T29/49906
Claims Analysis
Total Claims: 64
Claim 1
Independent Claim
108 words
A process for paving or sealing an interior surface of a hollow organ or tissue lumen comprising providing a thermoplastic material in a fluent state in a hollow organ or tissue lumen at a location requiring structural support, reconfiguring the thermoplastic material to form a layer of thermoplastic material on the interior surface, allowing the thermoplastic material to be converted into a non-fluent state in intimate and conforming contact with the tissue surface thereby paving or sealing the hollow organ or tissue lumen, and allowing the material to remain in intimate and conforming contact with the interior surface for a period of time effective for said structural support.
Claim 2
Dependent Claim
108 words
A process for paving or sealing an interior surface of a hollow organ or tissue lumen comprising providing a thermoplastic material in a fluent state in a hollow organ or tissue lumen at a location requiring structural support, reconfiguring the thermoplastic material to form a layer of thermoplastic material on the interior surface, allowing the thermoplastic material to be converted into a non-fluent state in intimate and conforming contact with the tissue surface thereby paving or sealing the hollow organ or tissue lumen, and allowing the material to remain in intimate and conforming contact with the interior surface for a period of time effective for said structural support.
Claim 3
Dependent Claim
24 words
A process as in claim 1, comprising using a catheter to position the thermoplastic material while the thermoplastic material is in a fluent state.
Claim 4
Dependent Claim
43 words
A process as in claim 1, comprising introducing a preshaped thermoplastic material into the hollow organ or tissue lumen in a non-fluent state, rendering the material fluent in the hollow organ or tissue lumen, and subsequently applying the material to the interior surface.
Claim 5
Dependent Claim
18 words
A process as in claim 3, comprising rendering the thermoplastic material fluent by applying heat to the material.
Claim 6
Dependent Claim
19 words
A process as in claim 4, comprising rendering the thermoplastic material fluent by applying to the material heated liquid.
Claim 7
Dependent Claim
127 words
A process as in claim 4, comprising providing the thermoplastic material in the hollow organ or tissue lumen with a catheter, and reconfiguring the material with the catheter, the catheter comprising an elongate tubular shaft having a distal end insertable into a patient and a proximal end adapted to remain outside of the patient, an expansile member at the distal end of the shaft, and a lumen associated with the shaft that provides fluid communication between the proximal end of the shaft and an interior surface of the expansile member, and the step of rendering the thermoplastic material fluent involves contacting the material with an exterior wall of the expansile member and delivering a heated liquid to the interior wall of the expansile member through the lumen.
Claim 8
Dependent Claim
22 words
A process as in claim 4, comprising rendering the thermoplastic material fluent by applying to the material electromagnetic radiation thereby heating it.
Claim 9
Dependent Claim
20 words
A process as in claim 7, comprising irradiating the thermoplastic material through an optical fiber internal of the catheter shaft.
Claim 10
Dependent Claim
15 words
A process as in claim 8, wherein the optical fiber is connected to a laser.
Claim 11
Dependent Claim
72 words
A process for paving or sealing an interior surface of a hollow organ or a tissue lumen comprising providing a biodegradable thermoplastic material in a fluent state in the hollow organ or tissue lumen, reconfiguring the biodegradable thermoplastic material to form a layer of thermoplastic material on the interior surface, and allowing the biodegradable thermoplastic material to be converted into a non-fluent state in intimate and conforming contact with the tissue surface.
Claim 12
Dependent Claim
72 words
A process for paving or sealing an interior surface of a hollow organ or a tissue lumen comprising providing a biodegradable thermoplastic material in a fluent state in the hollow organ or tissue lumen, reconfiguring the biodegradable thermoplastic material to form a layer of thermoplastic material on the interior surface, and allowing the biodegradable thermoplastic material to be converted into a non-fluent state in intimate and conforming contact with the tissue surface.
Claim 13
Dependent Claim
14 words
A process as in claim 10, wherein the thermoplastic material contains a therapeutic agent.
Claim 14
Dependent Claim
18 words
A process as in claim 10, wherein the thermoplastic material comprises a plurality of polymers containing therapeutic agents.
Claim 15
Dependent Claim
24 words
A process as in claim 10, comprising using a catheter to position the thermoplastic material while the thermoplastic material is in a fluent state.
Claim 16
Dependent Claim
17 words
A process as in claim 10, wherein the thermoplastic material contains living cells which promote organ regeneration.
Claim 17
Dependent Claim
31 words
A process as in claim 10, further comprising allowing the non-fluent thermoplastic material to remain in intimate and conforming contact with the tissue surface for a therapeutically effective period of time.
Claim 18
Dependent Claim
32 words
A process as in claim 10, further comprising allowing the thermoplastic material to remain in intimate and conforming contact with the tissue surface for a period of time effective to prevent restenosis.
Claim 19
Dependent Claim
43 words
A process as in claim 10, comprising introducing a preshaped thermoplastic material into the hollow organ or tissue lumen in a non-fluent state, rendering the material fluent in the hollow organ or tissue lumen, and subsequently applying the material to the interior surface.
Claim 20
Dependent Claim
18 words
A process as in claim 17, comprising rendering the thermoplastic material fluent by applying heat to the material.
Claim 21
Dependent Claim
19 words
A process as in claim 18, comprising rendering the thermoplastic material fluent by applying to the material heated liquid.
Claim 22
Dependent Claim
127 words
A process as in claim 18, comprising providing the thermoplastic material in the hollow organ or tissue lumen with a catheter, and reconfiguring the material with the catheter, the catheter comprising an elongate tubular shaft having a distal end insertable into a patient and a proximal end adapted to remain outside of the patient, an expansile member at the distal end of the shaft, and a lumen associated with the shaft that provides fluid communication between the proximal end of the shaft and an interior surface of the expansile member, and the step of rendering the thermoplastic material fluent involves contacting the material with an exterior wall of the expansile member and delivering a heated liquid to the interior wall of the expansile member through the lumen.
Claim 23
Dependent Claim
22 words
A process as in claim 18, comprising rendering the thermoplastic material fluent by applying to the material electromagnetic radiation thereby heating it.
Claim 24
Dependent Claim
20 words
A process as in claim 21, comprising irradiating the thermoplastic material through a optical fiber internal of the catheter shaft.
Claim 25
Dependent Claim
15 words
A process as in claim 22, wherein the optical fiber is connected to a laser.
Claim 26
Dependent Claim
74 words
A process for paving or sealing an interior surface of a hollow organ or a tissue lumen comprising providing a thermoplastic material that contains a therapeutic agent in a fluent state in the hollow organ or tissue lumen, reconfiguring the thermoplastic material to form a layer of thermoplastic material on the interior surface, and allowing the thermoplastic material to be converted into a non-fluent state in intimate and conforming contact with the tissue surface.
Claim 27
Dependent Claim
74 words
A process for paving or sealing an interior surface of a hollow organ or a tissue lumen comprising providing a thermoplastic material that contains a therapeutic agent in a fluent state in the hollow organ or tissue lumen, reconfiguring the thermoplastic material to form a layer of thermoplastic material on the interior surface, and allowing the thermoplastic material to be converted into a non-fluent state in intimate and conforming contact with the tissue surface.
Claim 28
Dependent Claim
18 words
A process as in claim 24, wherein the thermoplastic material comprises a plurality of polymers containing therapeutic agents.
Claim 29
Dependent Claim
24 words
A process as in claim 24, comprising using a catheter to position the thermoplastic material while the thermoplastic material is in a fluent state.
Claim 30
Dependent Claim
17 words
A process as in claim 24, wherein the thermoplastic material contains living cells which promote organ regeneration.
Claim 31
Dependent Claim
31 words
A process as in claim 24, further comprising allowing the non-fluent thermoplastic material to remain in intimate and conforming contact with the tissue surface for a therapeutically effective period of time.
Claim 32
Dependent Claim
32 words
A process as in claim 24, further comprising allowing the thermoplastic material to remain in intimate and conforming contact with the tissue surface for a period of time effective to prevent restenosis.
Claim 33
Dependent Claim
43 words
A process as in claim 24, comprising introducing a preshaped thermoplastic material into the hollow organ or tissue lumen in a non-fluent state, rendering the material fluent in the hollow organ or tissue lumen, and subsequently applying the material to the interior surface.
Claim 34
Dependent Claim
18 words
A process as in claim 30, comprising rendering the thermoplastic material fluent by applying heat to the material.
Claim 35
Dependent Claim
19 words
A process as in claim 31, comprising rendering the thermoplastic material fluent by applying to the material heated liquid.
Claim 36
Dependent Claim
127 words
A process as in claim 31, comprising providing the thermoplastic material in the hollow organ or tissue lumen with a catheter, and reconfiguring the material with the catheter, the catheter comprising an elongate tubular shaft having a distal end insertable into a patient and a proximal end adapted to remain outside of the patient, an expansile member at the distal end of the shaft, and a lumen associated with the shaft that provides fluid communication between the proximal end of the shaft and an interior surface of the expansile member, and the step of rendering the thermoplastic material fluent involves contacting the material with an exterior wall of the expansile member and delivering a heated liquid to the interior wall of the expansile member through the lumen.
Claim 37
Dependent Claim
22 words
A process as in claim 31, comprising rendering the thermoplastic material fluent by applying to the material electromagnetic radiation thereby heating it.
Claim 38
Dependent Claim
20 words
A process as in claim 34, comprising irradiating the thermoplastic material through a optical fiber internal of the catheter shaft.
Claim 39
Dependent Claim
15 words
A process as in claim 35, wherein the optical fiber is connected to a laser.
Claim 40
Dependent Claim
78 words
A process for paving or sealing an interior surface of a hollow organ or a tissue lumen comprising providing a thermoplastic material that comprises a plurality of polymers containing therapeutic agents in a fluent state in the hollow organ or tissue lumen, reconfiguring the thermoplastic material to form a layer of thermoplastic material on the interior surface, and allowing the thermoplastic material to be converted into a non-fluent state in intimate and conforming contact with the tissue surface.
Claim 41
Dependent Claim
78 words
A process for paving or sealing an interior surface of a hollow organ or a tissue lumen comprising providing a thermoplastic material that comprises a plurality of polymers containing therapeutic agents in a fluent state in the hollow organ or tissue lumen, reconfiguring the thermoplastic material to form a layer of thermoplastic material on the interior surface, and allowing the thermoplastic material to be converted into a non-fluent state in intimate and conforming contact with the tissue surface.
Claim 42
Dependent Claim
24 words
A process as in claim 37, comprising using a catheter to position the thermoplastic material while the thermoplastic material is in a fluent state.
Claim 43
Dependent Claim
17 words
A process as in claim 37, wherein the thermoplastic material contains living cells which promote organ regeneration.
Claim 44
Dependent Claim
31 words
A process as in claim 37, further comprising allowing the non-fluent thermoplastic material to remain in intimate and conforming contact with the tissue surface for a therapeutically effective period of time.
Claim 45
Dependent Claim
32 words
A process as in claim 37, further comprising allowing the thermoplastic material to remain in intimate and conforming contact with the tissue surface for a period of time effective to prevent restenosis.
Claim 46
Dependent Claim
43 words
A process as in claim 37, comprising introducing a preshaped thermoplastic material into the hollow organ or tissue lumen in a non-fluent state, rendering the material fluent in the hollow organ or tissue lumen, and subsequently applying the material to the interior surface.
Claim 47
Dependent Claim
18 words
A process as in claim 42, comprising rendering the thermoplastic material fluent by applying heat to the material.
Claim 48
Dependent Claim
19 words
A process as in claim 43, comprising rendering the thermoplastic material fluent by applying to the material heated liquid.
Claim 49
Dependent Claim
127 words
A process as in claim 43, comprising providing the thermoplastic material in the hollow organ or tissue lumen with a catheter, and reconfiguring the material with the catheter, the catheter comprising an elongate tubular shaft having a distal end insertable into a patient and a proximal end adapted to remain outside of the patient, an expansile member at the distal end of the shaft, and a lumen associated with the shaft that provides fluid communication between the proximal end of the shaft and an interior surface of the expansile member, and the step of rendering the thermoplastic material fluent involves contacting the material with an exterior wall of the expansile member and delivering a heated liquid to the interior wall of the expansile member through the lumen.
Claim 50
Dependent Claim
22 words
A process as in claim 43, comprising rendering the thermoplastic material fluent by applying to the material electromagnetic radiation thereby heating it.
Claim 51
Dependent Claim
20 words
A process as in claim 46, comprising irradiating the thermoplastic material through a optical fiber internal of the catheter shaft.
Claim 52
Dependent Claim
15 words
A process as in claim 47, wherein the optical fiber is connected to a laser.
Claim 53
Dependent Claim
77 words
A process for paving or sealing an interior surface of a hollow organ or a tissue lumen comprising providing a thermoplastic material that contains living cells which promote organ regeneration in a fluent state in the hollow organ or tissue lumen, reconfiguring the thermoplastic material to form a layer of thermoplastic material on the interior surface, and allowing the thermoplastic material to be converted into a non-fluent state in intimate and conforming contact with the tissue surface.
Claim 54
Dependent Claim
77 words
A process for paving or sealing an interior surface of a hollow organ or a tissue lumen comprising providing a thermoplastic material that contains living cells which promote organ regeneration in a fluent state in the hollow organ or tissue lumen, reconfiguring the thermoplastic material to form a layer of thermoplastic material on the interior surface, and allowing the thermoplastic material to be converted into a non-fluent state in intimate and conforming contact with the tissue surface.
Claim 55
Dependent Claim
24 words
A process as in claim 49, comprising using a catheter to position the thermoplastic material while the thermoplastic material is in a fluent state.
Claim 56
Dependent Claim
31 words
A process as in claim 44, further comprising allowing the non-fluent thermoplastic material to remain in intimate and conforming contact with the tissue surface for a therapeutically effective period of time.
Claim 57
Dependent Claim
32 words
A process as in claim 49, further comprising allowing the thermoplastic material to remain in intimate and conforming contact with the tissue surface for a period of time effective to prevent restenosis.
Claim 58
Dependent Claim
43 words
A process as in claim 49, comprising introducing a preshaped thermoplastic material into the hollow organ or tissue lumen in a non-fluent state, rendering the material fluent in the hollow organ or tissue lumen, and subsequently applying the material to the interior surface.
Claim 59
Dependent Claim
18 words
A process as in claim 53, comprising rendering the thermoplastic material fluent by applying heat to the material.
Claim 60
Dependent Claim
19 words
A process as in claim 54, comprising rendering the thermoplastic material fluent by applying to the material heated liquid.
Claim 61
Dependent Claim
127 words
A process as in claim 54, comprising providing the thermoplastic material in the hollow organ or tissue lumen with a catheter, and reconfiguring the material with the catheter, the catheter comprising an elongate tubular shaft having a distal end insertable into a patient and a proximal end adapted to remain outside of the patient, an expansile member at the distal end of the shaft, and a lumen associated with the shaft that provides fluid communication between the proximal end of the shaft and an interior surface of the expansile member, and the step of rendering the thermoplastic material fluent involves contacting the material with an exterior wall of the expansile member and delivering a heated liquid to the interior wall of the expansile member through the lumen.
Claim 62
Dependent Claim
22 words
A process as in claim 54, comprising rendering the thermoplastic material fluent by applying to the material electromagnetic radiation thereby heating it.
Claim 63
Dependent Claim
20 words
A process as in claim 57, comprising irradiating the thermoplastic material through a optical fiber internal of the catheter shaft.
Claim 64
Dependent Claim
15 words
A process as in claim 58, wherein the optical fiber is connected to a laser.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-10-06 | 2001-04-07 | 2001-10-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-10-06 | 2005-04-07 | 2005-10-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-10-06 | 2009-04-07 | 2009-10-07 | $7700.00 | Window Closed / Lapsed |