US5492763A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Infection resistant medical devices and process
Assignee: Spire Corp
•
Filing: 1994-02-10
•
Granted: 1996-02-20
•
Expires: 2014-02-10
Abstract
Abstract A medical device provided with a subsurface bacteriostatic/bactericidal stratum to a predetermined depth is disclosed. The bacteriostatic/bactericidal stratum is introduced into the medical device by ion implantation of sufficient concentration to impart thereto the desired bacteriostatic/bactericidal property. The acquired bacteriostatic/bactericidal property has a useful life coterminal with the device. The treated medical device remains biocompatible, is non-leaching and, depending on the specific device, also is thromboresistant.
Inventors
- 👤 John E. Barry
- 👤 Piran Sioshansi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:49
CPC Classifications
A; A61; A61L; A61L31/00; A61L31/14; A61L31/16; A61L27/00; A61L27/50; A61L27/54; A61L29/00; A61L29/14; A61L29/16; A61L2300/00; A61L2300/10; A61L2300/102; A61L2300/40; A61L2300/404; A61M; A61M25/00; A61M25/0043; A61M2025/0056; Y; Y10; Y10S; Y10S604/00; Y10S604/905; Y10T; Y10T428/00; Y10T428/13; Y10T428/131; Y10T428/1317; Y10T428/1321; Y10T428/1328; Y10T428/1331; Y10T428/1352; Y10T428/1355; Y10T428/31504; Y10T428/31678
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
64 words
A biomedical implant for insertion within a subject, comprising an implantable biocompatible structure formed from a unitary polymeric material having a tissue-engaging outer surface, the tissue-engaging outer surface having embedded therein atoms of a bactericidal material to form a substantially nonleaching bactericidal subsurface stratum, the atoms extending only partially through the implantable biocompatible structure to a predetermined depth from the tissue engaging outer surface.
Claim 2
Dependent Claim
64 words
A biomedical implant for insertion within a subject, comprising an implantable biocompatible structure formed from a unitary polymeric material having a tissue-engaging outer surface, the tissue-engaging outer surface having embedded therein atoms of a bactericidal material to form a substantially nonleaching bactericidal subsurface stratum, the atoms extending only partially through the implantable biocompatible structure to a predetermined depth from the tissue engaging outer surface.
Claim 3
Dependent Claim
27 words
The biomedical implant of claim 1 wherein the atoms of the bactericidal material extend below the tissue-engaging outer surface to a depth less than about 2.0 microns.
Claim 4
Dependent Claim
36 words
The biomedical implant of claim 1 wherein the atoms of the bactericidal material are embedded within the tissue-engaging outer surface by implantation of ions with a current density of at least about 0.01 μA/cm 2 .
Claim 5
Dependent Claim
16 words
The biomedical implant of claim 1 wherein the atoms of the bactericidal material comprise metal atoms.
Claim 6
Dependent Claim
27 words
The biomedical implant of claim 1 wherein the atoms of the bactericidal material comprise at least one of silver, gold, copper, platinum, iridium, magnesium, and palladium atoms.
Claim 7
Dependent Claim
79 words
A biomedical implant for insertion within a subject, comprising an implantable member formed from a unitary polymeric .material having a tissue-engaging outer surface having embedded therein atoms of a bactericidal material, the atoms being embedded by ion implantation, and being secured within the member and extending into the tissue-engaging outer surface to a depth between about 0.01 microns and about 2.0 microns, whereby the atoms of the bactericidal material remain effective for the useful life of the implantable member.
Claim 8
Dependent Claim
79 words
A biomedical implant for insertion within a subject, comprising an implantable member formed from a unitary polymeric .material having a tissue-engaging outer surface having embedded therein atoms of a bactericidal material, the atoms being embedded by ion implantation, and being secured within the member and extending into the tissue-engaging outer surface to a depth between about 0.01 microns and about 2.0 microns, whereby the atoms of the bactericidal material remain effective for the useful life of the implantable member.
Claim 9
Dependent Claim
24 words
The biomedical implant of claim 6 wherein the atoms of the bactericidal material have a concentration of at least 10 15 ions/cm 3 .
Claim 10
Dependent Claim
16 words
The biomedical implant of claim 6 wherein the atoms of the bactericidal material comprise metal atoms.
Claim 11
Dependent Claim
27 words
The biomedical implant of claim 6 wherein the atoms of the bactericidal material comprise at least one of silver, gold, copper, platinum, iridium, magnesium and palladium atoms.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-02-19 | 1999-08-21 | 2000-02-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-02-19 | 2003-08-21 | 2004-02-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-02-19 | 2007-08-21 | 2008-02-20 | $7700.00 | Window Closed / Lapsed |