Patent US5851231A successfully refreshed from Google Patents.
US5851231A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Intralumenal drug eluting prosthesis
Assignee: Medtronic Inc
•
Filing: 1996-12-04
•
Granted: 1998-12-22
•
Expires: 2016-12-04
Abstract
Abstract A prosthesis for insertion into a lumen to limit restenosis of the lumen. The prosthesis carries restenosis-limiting drugs which elute after the device is positioned in the lumen.
Inventors
- 👤 Rodney G. Wolff
- 👤 Vincent W. Hull
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 07:54
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/95; A61F2/958; A61F2/82; A61F2/86; A61F2/90; A61L; A61L31/00; A61L31/14; A61L31/16; A61M; A61M31/00; A61M31/002; D; D04; D04C; D04C1/00; D04C1/06; A61F2/852; A61F2210/00; A61F2210/0076; A61F2250/00; A61F2250/0014; A61F2250/0048; A61F2250/0058; A61F2250/006; A61F2250/0063; A61F2250/0067; A61L2300/00; A61L2300/40; A61L2300/416; D10; D10B; D10B2509/00; D10B2509/06
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
180 words
A device for local intralumenal administration of drugs comprising: (a) a body including a plurality of support elements forming a open-ended, radially expandable, self-supporting tubular structure having an interior surface and an exterior surface, the tubular structure including as support elements a plurality of helical elements, each of which is wound in a helix configuration along a center line of the tubular body as a common axis, said helical elements wound in opposing helical directions such that the tubular body is variable in radial diameter under axial movement of opposite ends of the body relative to each other; (b) a flexible, polymeric filament attached to the support elements of the body, at least a portion of the filament exposed at an exterior surface of the tubular body; (c) a drug compounded into the polymeric filament such that the drug is delivered to the body lumen when the tubular body is radially expanded into contact with the portion of the body lumen to be treated; and (d) a radially expandable stent of malleable metal in supporting contact with the tubular structure.
Claim 2
Independent Claim
180 words
A device for local intralumenal administration of drugs comprising: (a) a body including a plurality of support elements forming a open-ended, radially expandable, self-supporting tubular structure having an interior surface and an exterior surface, the tubular structure including as support elements a plurality of helical elements, each of which is wound in a helix configuration along a center line of the tubular body as a common axis, said helical elements wound in opposing helical directions such that the tubular body is variable in radial diameter under axial movement of opposite ends of the body relative to each other; (b) a flexible, polymeric filament attached to the support elements of the body, at least a portion of the filament exposed at an exterior surface of the tubular body; (c) a drug compounded into the polymeric filament such that the drug is delivered to the body lumen when the tubular body is radially expanded into contact with the portion of the body lumen to be treated; and (d) a radially expandable stent of malleable metal in supporting contact with the tubular structure.
Claim 3
Independent Claim
180 words
A device for local intralumenal administration of drugs comprising: (a) a body including a plurality of support elements forming a open-ended, radially expandable, self-supporting tubular structure having an interior surface and an exterior surface, the tubular structure including as support elements a plurality of helical elements, each of which is wound in a helix configuration along a center line of the tubular body as a common axis, said helical elements wound in opposing helical directions such that the tubular body is variable in radial diameter under axial movement of opposite ends of the body relative to each other; (b) a flexible, polymeric filament attached to the support elements of the body, at least a portion of the filament exposed at an exterior surface of the tubular body; (c) a drug compounded into the polymeric filament such that the drug is delivered to the body lumen when the tubular body is radially expanded into contact with the portion of the body lumen to be treated; and (d) a radially expandable stent of resilient metal in supporting contact with the tubular structure.
Claim 4
Independent Claim
180 words
A device for local intralumenal administration of drugs comprising: (a) a body including a plurality of support elements forming a open-ended, radially expandable, self-supporting tubular structure having an interior surface and an exterior surface, the tubular structure including as support elements a plurality of helical elements, each of which is wound in a helix configuration along a center line of the tubular body as a common axis, said helical elements wound in opposing helical directions such that the tubular body is variable in radial diameter under axial movement of opposite ends of the body relative to each other; (b) a flexible, polymeric filament attached to the support elements of the body, at least a portion of the filament exposed at an exterior surface of the tubular body; (c) a drug compounded into the polymeric filament such that the drug is delivered to the body lumen when the tubular body is radially expanded into contact with the portion of the body lumen to be treated; and (d) a radially expandable stent of resilient metal in supporting contact with the tubular structure.
Claim 5
Independent Claim
137 words
A device for local intralumenal administration of drugs comprising: (a) a body including a plurality of bioabsorbable polymeric elements forming an open-ended, radially expandable tubular structure having an interior surface and an exterior surface, the tubular structure including a plurality of elements joined together such that the tubular body is variable in radial diameter; (b) a flexible, bioabsorbable polymeric filament attached to the elements of the body such that at least a portion of the filament is exposed at an exterior surface of the tubular body; (c) a drug compounded into the polymeric filament such that the drug is delivered to the body lumen when the tubular body is radially expanded into contact with the portion of the body lumen to be treated; and (d) a radially expandable metal stent in supporting contact with the tubular body.
Claim 6
Independent Claim
137 words
A device for local intralumenal administration of drugs comprising: (a) a body including a plurality of bioabsorbable polymeric elements forming an open-ended, radially expandable tubular structure having an interior surface and an exterior surface, the tubular structure including a plurality of elements joined together such that the tubular body is variable in radial diameter; (b) a flexible, bioabsorbable polymeric filament attached to the elements of the body such that at least a portion of the filament is exposed at an exterior surface of the tubular body; (c) a drug compounded into the polymeric filament such that the drug is delivered to the body lumen when the tubular body is radially expanded into contact with the portion of the body lumen to be treated; and (d) a radially expandable metal stent in supporting contact with the tubular body.
Claim 7
Dependent Claim
24 words
The device of claim 3 also comprising a barrier coating of polymeric material on the drug-containing filament to limit the rate of drug elution.
Claim 8
Dependent Claim
28 words
The device of claim 3 wherein the drug is selected from the group consisting of antiplatelet drugs, anticoagulant drugs, anti-inflammatory drugs, antireplicate drugs and combinations of said drugs.
Claim 9
Dependent Claim
16 words
The device of claim 3 wherein the stent is a radially expandable stent of malleable metal.
Claim 10
Dependent Claim
16 words
The device of claim 3 wherein the stent is a radially expandable stent of resilient metal.
Claim 11
Dependent Claim
33 words
The device of claim 3 wherein the elements of the tubular body are joined together by weaving and wherein the flexible, polymeric filament is woven into the support elements of the tubular body.
Claim 12
Dependent Claim
22 words
The device of claim 3 wherein the polymeric filament is attached to the elements of the tubular body by a bonded juncture.
References Cited (Backward Citations)
US3657744A
Cited
US4326532A
Cited
US4678466A
Cited
US4655771B1
Cited
WO1983003752A1
Cited
US4655771A
Cited
GB2153235A
Cited
US4923470A
Cited
US4871365A
Cited
US4650466A
Cited
US4739762B1
Cited
US4739762A
Cited
US5102417A
Cited
US4944767A
Cited
US5028597A
Cited
US5061275A
Cited
US4872874A
Cited
US5059211A
Cited
US5047020A
Cited
WO1989003232A1
Cited
US4886062A
Cited
US5019096A
Cited
US5165919A
Cited
US5213580A
Cited
EP0357003B1
Cited
US5053048A
Cited
US5062829A
Cited
US4990158A
Cited
US5015253A
Cited
US5171262A
Cited
US5152783A
Cited
US5152784A
Cited
US5234456A
Cited
US5545208A
Cited
US5304121A
Cited
US5674192A
Cited
US5551954A
Cited
US5464450A
Cited
US5500013A
Cited
US5282823A
Cited
US5443496A
Cited
US5591224A
Cited
US5628785A
Cited
US5651174A
Cited
US5366504A
Cited
US5383928A
Cited
US5443458A
Cited
US5643309A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-12-21 | 2002-06-22 | 2002-12-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-12-21 | 2006-06-22 | 2006-12-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-12-21 | 2010-06-22 | 2010-12-22 | $7700.00 | Window Closed / Lapsed |