US5464450A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Biodegradable drug delivery vascular stent
Assignee: Boston Scientific Scimed Inc
•
Filing: 1994-03-21
•
Granted: 1995-11-07
•
Expires: 2014-03-21
Abstract
Abstract A stent made of biodegradable material includes a drug that is released at a rate controlled by the rate of degradation of the biodegradable material. The stent includes a main body of a generally tubular shape. The main body may further include a plurality of apertures extending therethrough and a slot defined by opposing edges which permits insertion and positioning of the stent.
Inventors
- 👤 Paul J. Buscemi
- 👤 Elizabeth A. Stejskal
- 👤 II Donald F. Palme
- 👤 Lixiao Wang
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:52
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/86; A61F2/88; A61L; A61L31/00; A61L31/14; A61L31/148; A61L31/16; A61F2/95; A61F2/958; A61F2210/00; A61F2210/0004; A61F2210/0014; A61F2210/0023; A61F2250/00; A61F2250/0058; A61F2250/0067; A61L2300/00; A61L2300/60; A61L2300/602; A61L2300/604
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
172 words
A biodegradable self-expanding stent for insertion into a lumen of a vessel of a living being, the stent being substantially completely biodegradable the stent comprising: (a) a generally tubular biodegradable main body surrounded by an array consisting of individual biodegradable materials having individual rates of degradation, the individual biodegradable materials contain a plurality of drugs, said drugs being released into the lumen of the vessel as the biodegradable materials degrade, at rates controlled by the rates of degradation of the biodegradable materials; (b) said tubular main body including a slot extending lengthwise through the main body and defined by opposing edges of the main body wherein the opposing edges must be moved toward each other under compression in order to transport the biodegradable stent through a vessel of a living being; and said array being annularly aligned oriented fibers disposed about and attached to said tubular main body and so oriented to provide a self-expanding, spring force in an outward, substantially radial direction to increase the effective diameter of said main body.
Claim 2
Dependent Claim
172 words
A biodegradable self-expanding stent for insertion into a lumen of a vessel of a living being, the stent being substantially completely biodegradable the stent comprising: (a) a generally tubular biodegradable main body surrounded by an array consisting of individual biodegradable materials having individual rates of degradation, the individual biodegradable materials contain a plurality of drugs, said drugs being released into the lumen of the vessel as the biodegradable materials degrade, at rates controlled by the rates of degradation of the biodegradable materials; (b) said tubular main body including a slot extending lengthwise through the main body and defined by opposing edges of the main body wherein the opposing edges must be moved toward each other under compression in order to transport the biodegradable stent through a vessel of a living being; and said array being annularly aligned oriented fibers disposed about and attached to said tubular main body and so oriented to provide a self-expanding, spring force in an outward, substantially radial direction to increase the effective diameter of said main body.
Claim 3
Dependent Claim
30 words
The stent of claim 1 wherein the tubular biodegradable main body includes a plurality of layers made from art array consisting of individual biodegradable materials that degrade at different rates.
Claim 4
Dependent Claim
47 words
The biodegradable stent of claim 1 wherein the tubular biodegradable main body includes: an outer surface having a generally tubular shape for contacting tissue of a vessel when the main body is placed in a living being; and a plurality of apertures extending through the main body.
Claim 5
Dependent Claim
192 words
A biodegradable, self-expanding stent for insertion into the lumen of a vessel of a living being, the stent being substantially completely biodegradable the stent comprising: (a) a generally tubular biodegradable main body surrounded by an array consisting of individual biodegradable materials that degrade at different rates, said individual biodegradable materials containing a plurality of drugs, said drugs being released into the vessel lumen as the biodegradable materials degrade, said tubular body having an outer surface of generally tubular shape for contacting tissue of a vessel said array comprising annularly aligned oriented fibers disposed about and attached to said tubular main body and so oriented to provide a self-expanding, spring force in an outward, substantially radial direction to increase the effective diameter of said main body; (b) a slot extending lengthwise through the main body and defined by opposing edges of the main body wherein the opposing edges must be moved toward each other under compression in order to transport the biodegradable stent through a vessel of a living being, said slot allowing compression of the main body to decrease its diameter; and (c) a plurality of apertures extending through the main body.
Claim 6
Dependent Claim
192 words
A biodegradable, self-expanding stent for insertion into the lumen of a vessel of a living being, the stent being substantially completely biodegradable the stent comprising: (a) a generally tubular biodegradable main body surrounded by an array consisting of individual biodegradable materials that degrade at different rates, said individual biodegradable materials containing a plurality of drugs, said drugs being released into the vessel lumen as the biodegradable materials degrade, said tubular body having an outer surface of generally tubular shape for contacting tissue of a vessel said array comprising annularly aligned oriented fibers disposed about and attached to said tubular main body and so oriented to provide a self-expanding, spring force in an outward, substantially radial direction to increase the effective diameter of said main body; (b) a slot extending lengthwise through the main body and defined by opposing edges of the main body wherein the opposing edges must be moved toward each other under compression in order to transport the biodegradable stent through a vessel of a living being, said slot allowing compression of the main body to decrease its diameter; and (c) a plurality of apertures extending through the main body.
Claim 7
Dependent Claim
33 words
The biodegradable stent of claim 4 wherein the fiber shape of the biodegradable materials is a hollow fiber shape and drugs are incorporated in the biodegradable materials enclosed within the hollow fiber shape.
References Cited (Backward Citations)
US3636956A
Cited
US3975371A
Cited
US3799172A
Cited
US4141364A
Cited
US4183102A
Cited
US4850999A
Cited
US4787899A
Cited
US4580447A
Cited
US4580568A
Cited
US4923470A
Cited
US4997440A
Cited
US4871365A
Cited
US4892098A
Cited
US4770176A
Cited
US4690684A
Cited
US4733665B1
Cited
US4739762B1
Cited
US4776337A
Cited
US4739762A
Cited
US4733665A
Cited
US4733665C2
Cited
US4776337B1
Cited
US4681110A
Cited
US4768507A
Cited
US4792336A
Cited
US4942875A
Cited
US4753236A
Cited
EP0246998A2
Cited
US4787399A
Cited
US4740207A
Cited
US4957508A
Cited
US4907336A
Cited
US5059211A
Cited
US4795458A
Cited
US4886062A
Cited
US4820298A
Cited
US4877030A
Cited
US5019096A
Cited
US4830003A
Cited
CA2005199A1
Cited
CA2008312A1
Cited
US5147400A
Cited
US4990158A
Cited
US4990155A
Cited
US4994033A
Cited
CA2025626A1
Cited
US5078736A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-11-06 | 1999-05-08 | 1999-11-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-11-06 | 2003-05-08 | 2003-11-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-11-06 | 2007-05-08 | 2007-11-07 | $7700.00 | Window Closed / Lapsed |