US5152783A
Expired / Lapsed
US
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Antithrombogenic material
Assignee: Sony Corp
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Filing: 1990-08-21
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Granted: 1992-10-06
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Expires: 2010-08-21
Abstract
Abstract An antithrombogenic material having its surface modified by ion implantation is disclosed. This antithrombogenic material may, for example, be a silicone material which has its surface modified by introducing functional groups on its surface by ion implantation. The material exhibits improved compatibility to blood due to introduction of the functional groups by ion implantation and the doping effect of the implanted elements.
Inventors
- 👤 Yoshiaki Suzuki
- 👤 Masahiro Kusakabe
- 👤 Iwaki Masaya
- 👤 Kiyoko Kusakabe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 00:33
CPC Classifications
A; A61; A61L; A61L33/00; A61L33/0076; A61L33/0082; B; B29; B29C; B29C59/00; B29C59/16; B29C35/00; B29C35/02; B29C35/08; B29C35/0866; B29C2035/0872; B29K; B29K2083/00
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
64 words
A biocompatible antithrombogenic device comprising: a silicone material having an external surface; and ions selected from the group consisting of H + , He + , Ne + , Na + , O 2 + , K + , Ar + and mixtures thereof implanted on the surface of the silicone material in sufficient quantity to substantially suppress platelet accumulation when exposed to blood.
Claim 2
Dependent Claim
64 words
A biocompatible antithrombogenic device comprising: a silicone material having an external surface; and ions selected from the group consisting of H + , He + , Ne + , Na + , O 2 + , K + , Ar + and mixtures thereof implanted on the surface of the silicone material in sufficient quantity to substantially suppress platelet accumulation when exposed to blood.
Claim 3
Dependent Claim
56 words
A biocompatible antithrombogenic device comprising: a silicone material having an external surface; and functional groups selected from the group consisting of SiOH, SiH, CH 2 , CO, NH 2 , CO 2 H and mixtures thereof on the external surface of the silicone material in sufficient quantity to substantially suppress platelet accumulation when exposed to blood.
Claim 4
Dependent Claim
56 words
A biocompatible antithrombogenic device comprising: a silicone material having an external surface; and functional groups selected from the group consisting of SiOH, SiH, CH 2 , CO, NH 2 , CO 2 H and mixtures thereof on the external surface of the silicone material in sufficient quantity to substantially suppress platelet accumulation when exposed to blood.
Claim 5
Dependent Claim
24 words
The antithrombogenic device according to claim 2 wherein the functional groups are selected from the group consisting of CO, NH 2 and mixtures thereof.
Claim 6
Dependent Claim
26 words
The antithrombogenic device according to claim 1 wherein the ions are selected from the group consisting of H 30 , O 2 + and mixtures thereof.
Claim 7
Dependent Claim
19 words
The antithrombogenic device material according to claim 2 wherein the silicone material is a polymer having the formula ##STR2##
Claim 8
Dependent Claim
25 words
The antithrombogenic device according to claim 4 wherein the ions are O 2 + and CO functional groups are present on the silicone material surface.
Claim 9
Dependent Claim
24 words
The antithrombogenic device according to claim 4 wherein the ions are H + and SiOH functional groups are present on the silicone material surface.
Claim 10
Dependent Claim
32 words
The antithrombogenic device according to claim 3 wherein the functional groups are NH 2 , SiOH or SiH and further comprising N 2 + ions are implanted on the silicone material surface.
Claim 11
Dependent Claim
26 words
The antithrombogenic device according to claim 1 wherein the ions are He + and on the silicone material surface SiOH or SiH functional groups are present.
Claim 12
Dependent Claim
29 words
The antithrombogenic device according to claim 2 wherein the functional groups are SiOH, SiH or CO and further comprising C + ions are implanted on the silicone material surface.
Claim 13
Dependent Claim
26 words
The antithrombogenic device according to claim 1 wherein the ions are Ne + and SiOH and SiH functional groups are present on the silicone material surface.
Claim 14
Dependent Claim
31 words
The antithrombogenic device according to claim 1 wherein the ions are Na + and SiOH, SiH, CH 2 and CO 2 H functional groups are present on the silicone material surface.
Claim 15
Dependent Claim
27 words
The antithrombogenic device according to claim 1 wherein the ions are K + and SiOH and CH 2 functional groups are present on the silicone material surface.
Claim 16
Dependent Claim
28 words
The antithrombogenic device according to claim 1 wherein the ions are Ar + and SiOH, SiH and CH 2 functional groups are present on the silicone material surface.
Claim 17
Dependent Claim
27 words
The antithrombogenic device of claim 1 wherein the concentration of ions implanted on the silicone material surface is approximately between 1×10 12 and 3×10 17 per cm-2.
References Cited (Backward Citations)
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| 3.5 Years (Year 4) | 1995-10-06 | 1996-04-06 | 1996-10-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-10-06 | 2000-04-06 | 2000-10-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-10-06 | 2004-04-06 | 2004-10-06 | $7700.00 | Window Closed / Lapsed |