Patent US5885790A successfully refreshed from Google Patents.
US5885790A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Diagnostic compositions and devices utilizing same
Assignee: Roche Diabetes Care Inc
•
Filing: 1998-03-10
•
Granted: 1999-03-23
•
Expires: 2018-03-10
Abstract
Abstract A dry chemistry dye indicator composition provides improved shelf life, stable color indication end point and capability for a system at near normal pH. The novel dry chemistry dye indication system comprises 3-Methyl-6-(sodium sulfonate)-benzothiazolinone-(2)-hydrazone (MBTH-S). A preferred dye systems are based on the dye couple (MBTH-S) and 8-anilino-1-naphthalenesulfonate (ANS), and the dye couple MBTH-S and N-(3-sulfopropyl)analine. These dye indicator systems are used in conventional blood chemistry test strips and are particularly preferred for indication of glucose in blood.
Inventors
- 👤 Joel S. Douglas
- 👤 Karen R. Drexler
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:36
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/26; C12Q1/28; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/521; G01N33/523; C12Q2326/00; C12Q2326/32; Y; Y10; Y10S; Y10S435/00; Y10S435/808; Y10S435/814; Y10S435/97
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
49 words
A composition for a dry chemistry reagent indicator comprising: 3-Methyl-6-(M sulfonate)-benzothiazolinone-(2)-hydrazone, wherein M is a positive charge ion providing a stable aqueous salt thereof; a second dye component selected from the group consisting of 3.3-dimethylaminobenzoic acid, 3,5-dichloro-2-hydroxybenzenesulfonic acid, 8-anilino-1-naphthalenesulfonate, and N-(3-sulfopropyl)aniline; and an oxidase enzyme and/or a peroxidase enzyme.
Claim 2
Dependent Claim
49 words
A composition for a dry chemistry reagent indicator comprising: 3-Methyl-6-(M sulfonate)-benzothiazolinone-(2)-hydrazone, wherein M is a positive charge ion providing a stable aqueous salt thereof; a second dye component selected from the group consisting of 3.3-dimethylaminobenzoic acid, 3,5-dichloro-2-hydroxybenzenesulfonic acid, 8-anilino-1-naphthalenesulfonate, and N-(3-sulfopropyl)aniline; and an oxidase enzyme and/or a peroxidase enzyme.
Claim 3
Dependent Claim
14 words
The composition according to claim 1 where M is sodium, potassium or ammonium ion.
Claim 4
Dependent Claim
13 words
The composition according to claim 1 wherein the second dye component is 8-anilino-1-naphthalenesulfonate.
Claim 5
Dependent Claim
13 words
The composition according to claim 1 wherein the second dye component is N-(3-sulfopropyl)aniline.
References Cited (Backward Citations)
GB938029A
Cited
US3964871A
Cited
US4385114A
Cited
US4101381A
Cited
US4059407A
Cited
US4168205A
Cited
US4260679A
Cited
EP0007787A1
Cited
US4247631A
Cited
US4247297A
Cited
US4278439A
Cited
US4367285A
Cited
US4416983A
Cited
US4605629A
Cited
US4492754A
Cited
US4734360A
Cited
US4820632A
Cited
US5315035A
Cited
US5084382A
Cited
US4851335A
Cited
US5304468A
Cited
US5059394A
Cited
EP0328029A2
Cited
US5082626A
Cited
US5334508A
Cited
WO1990006372A1
Cited
US5306623A
Cited
US5453360A
Cited
DE4343082A1
Cited
JPH07311498A
Cited
US5526120A
Cited
US5563031A
Cited
EP0735369A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-03-22 | 2002-09-21 | 2003-03-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-03-22 | 2006-09-21 | 2007-03-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-03-22 | 2010-09-21 | 2011-03-23 | $7700.00 | Window Closed / Lapsed |