US5885790A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Diagnostic compositions and devices utilizing same
Assignee: Roche Diabetes Care Inc
•
Filing: 1998-03-10
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Granted: 1999-03-23
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Expires: 2018-03-10
Abstract
Abstract A dry chemistry dye indicator composition provides improved shelf life, stable color indication end point and capability for a system at near normal pH. The novel dry chemistry dye indication system comprises 3-Methyl-6-(sodium sulfonate)-benzothiazolinone-(2)-hydrazone (MBTH-S). A preferred dye systems are based on the dye couple (MBTH-S) and 8-anilino-1-naphthalenesulfonate (ANS), and the dye couple MBTH-S and N-(3-sulfopropyl)analine. These dye indicator systems are used in conventional blood chemistry test strips and are particularly preferred for indication of glucose in blood.
Inventors
- 👤 Joel S. Douglas
- 👤 Karen R. Drexler
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:27
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/26; C12Q1/28; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/521; G01N33/523; C12Q2326/00; C12Q2326/32; Y; Y10; Y10S; Y10S435/00; Y10S435/808; Y10S435/814; Y10S435/97
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
49 words
A composition for a dry chemistry reagent indicator comprising: 3-Methyl-6-(M sulfonate)-benzothiazolinone-(2)-hydrazone, wherein M is a positive charge ion providing a stable aqueous salt thereof; a second dye component selected from the group consisting of 3.3-dimethylaminobenzoic acid, 3,5-dichloro-2-hydroxybenzenesulfonic acid, 8-anilino-1-naphthalenesulfonate, and N-(3-sulfopropyl)aniline; and an oxidase enzyme and/or a peroxidase enzyme.
Claim 2
Dependent Claim
49 words
A composition for a dry chemistry reagent indicator comprising: 3-Methyl-6-(M sulfonate)-benzothiazolinone-(2)-hydrazone, wherein M is a positive charge ion providing a stable aqueous salt thereof; a second dye component selected from the group consisting of 3.3-dimethylaminobenzoic acid, 3,5-dichloro-2-hydroxybenzenesulfonic acid, 8-anilino-1-naphthalenesulfonate, and N-(3-sulfopropyl)aniline; and an oxidase enzyme and/or a peroxidase enzyme.
Claim 3
Dependent Claim
14 words
The composition according to claim 1 where M is sodium, potassium or ammonium ion.
Claim 4
Dependent Claim
13 words
The composition according to claim 1 wherein the second dye component is 8-anilino-1-naphthalenesulfonate.
Claim 5
Dependent Claim
13 words
The composition according to claim 1 wherein the second dye component is N-(3-sulfopropyl)aniline.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-03-22 | 2002-09-21 | 2003-03-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-03-22 | 2006-09-21 | 2007-03-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-03-22 | 2010-09-21 | 2011-03-23 | $7700.00 | Window Closed / Lapsed |