Patent US5458568A successfully refreshed from Google Patents.
US5458568A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Porous balloon for selective dilatation and drug delivery
Assignee: Mmc/gatx Partnership No1
•
Filing: 1993-09-17
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Granted: 1995-10-17
•
Expires: 2013-09-17
Abstract
Abstract A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively wetting a membrane within the device, making the membrane permeable and allowing transport of a drug across the membrane and into the passageway wall or body tissue.
Inventors
- 👤 Joel R. Racchini
- 👤 James E. Shapland
- 👤 Mark B. Knudson
- 👤 Jin Shimada
- 👤 Keith R. Hildebrand
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:48
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/104; A61M16/00; A61M16/04; A61M16/0475; A61M16/0477; A61M16/0481; A61M37/00; A61M37/0092; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/05; A61N1/18; A61N1/20; A61N1/30; A61N1/303; A61N1/306; A61N1/32; A61N1/325; A61M25/0043; A61M2025/0057; A61M2025/1043; A61M2025/105; A61N1/056; A61N2001/0585
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
111 words
A method of delivering a drug to internal body tissue, comprising the steps of: (a) providing a catheter having a non-wetted and controllably permeable porous membrane proximate said distal end of said catheter, said membrane having a predetermined pore size and defining a drug delivery chamber at said distal end of said catheter; (b) positioning said drug delivery chamber proximate said internal body tissue; (c) wetting said porous membrane with a fluid thereby making said membrane permeable, said fluid having a predetermined surface tension and a predetermined contact angle with the porous membrane; and (d) transporting said drug from said delivery chamber to said internal body tissue across said porous membrane.
Claim 2
Independent Claim
111 words
A method of delivering a drug to internal body tissue, comprising the steps of: (a) providing a catheter having a non-wetted and controllably permeable porous membrane proximate said distal end of said catheter, said membrane having a predetermined pore size and defining a drug delivery chamber at said distal end of said catheter; (b) positioning said drug delivery chamber proximate said internal body tissue; (c) wetting said porous membrane with a fluid thereby making said membrane permeable, said fluid having a predetermined surface tension and a predetermined contact angle with the porous membrane; and (d) transporting said drug from said delivery chamber to said internal body tissue across said porous membrane.
Claim 3
Dependent Claim
27 words
The method of claim 1, wherein said step of positioning further comprises positioning said drug delivery chamber in an internal elongated passageway proximate said internal body tissue.
Claim 4
Dependent Claim
18 words
The method of claim 2, further comprising the step of dilating said passageway by expanding said porous membrane.
Claim 5
Dependent Claim
25 words
The method of claim 1, wherein said step of wetting further comprises providing a fluid to said drug delivery chamber through said fluid delivery lumen.
Claim 6
Dependent Claim
18 words
The method of claim 4, wherein providing said fluid further comprises providing a wetting agent in said fluid.
Claim 7
Dependent Claim
18 words
The method of claim 5, wherein providing said wetting agent further comprises providing a surfactant in said fluid.
Claim 8
Dependent Claim
15 words
The method of claim 4, wherein said step of wetting further comprises pressurizing said fluid.
Claim 9
Dependent Claim
33 words
The method of claim 4, wherein said step of wetting further comprises providing a voltage gradient from said fluid in said drug delivery chamber to said internal body tissue across said porous membrane.
Claim 10
Dependent Claim
30 words
The method of claim 1, wherein said step of transporting further comprises providing a voltage gradient from said drug delivery chamber to said internal body tissue across said porous membrane.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-10-16 | 1999-04-17 | 1999-10-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-10-16 | 2003-04-17 | 2003-10-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-10-16 | 2007-04-17 | 2007-10-17 | $7700.00 | Window Closed / Lapsed |