Patent US5139527A successfully refreshed from Google Patents.
US5139527A
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US
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Biologic absorbable implant material for filling and closing soft tissue cavities and method of its preparation
Assignee: Oesterreichisches Institut fuer Haemoderivate
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Filing: 1990-08-06
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Granted: 1992-08-18
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Expires: 2010-08-06
Abstract
Abstract There is disclosed a biologic absorbable implant material for filling and closing soft-tissue cavities and for replacing soft-tissue parts, and a method of its preparation. The implant material consists essentially of bone tissue of human or animal origin, is decalcified, and the original protein content of the osseous hard substance is unchanged. By cross-linking of these native proteins with a cross-linking agent, a high elasticity, a good stability and a marked memory-effect are attained. The method for the preparation of the implant material includes degreasing, decalcification and cross-linking of the available proteins and then drying and sterilizing of the material.
Inventors
- 👤 Heinz Redl
- 👤 Gunther Schlag
- 👤 Nestor Pridun
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:59
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3604; A61L27/3608; A61L24/00; A61L24/0005; A61L24/04; A61L24/10; A61L24/102; A61L27/3683; A61L27/3695
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
89 words
A bioabsorbable soft tissue implant material for filling and closing soft-tissue cavities said implant material consists essentially of decalcified spongiosa bone tissue of human or animal origin prepared from spongiosa bone parts, having spongy consistency, and molded into shaped products, wherein said bone tissue has its native proteins cross-linked by a protein cross-linking agent so as to avoid osteoinductive effects, the pore volume of the material being 55 to 95%, said shaped products are elastic in the moistened condition and have a low hysteresis between loaded and unloaded conditions.
Claim 2
Dependent Claim
89 words
A bioabsorbable soft tissue implant material for filling and closing soft-tissue cavities said implant material consists essentially of decalcified spongiosa bone tissue of human or animal origin prepared from spongiosa bone parts, having spongy consistency, and molded into shaped products, wherein said bone tissue has its native proteins cross-linked by a protein cross-linking agent so as to avoid osteoinductive effects, the pore volume of the material being 55 to 95%, said shaped products are elastic in the moistened condition and have a low hysteresis between loaded and unloaded conditions.
Claim 3
Dependent Claim
15 words
An implant material as set forth in claim 1, in combination with pharmaceutically active substances.
Claim 4
Dependent Claim
35 words
An implant material as set forth in claim 1, which is compressible in the dry state, yet is capable of reassuming its original shape in the presence of moisture, thus exhibiting a marked memory effect.
Claim 5
Dependent Claim
20 words
An implant material as set forth in claim 1, wherein the maximum residual calcium content is 80 mMol/g wet weight.
Claim 6
Dependent Claim
20 words
An implant material as set forth in claim 1, in combination with a tissue adhesive based on fibrinogen or collagen.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-08-18 | 1996-02-17 | 1996-08-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-08-18 | 2000-02-17 | 2000-08-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-08-18 | 2004-02-17 | 2004-08-18 | $7700.00 | Window Closed / Lapsed |