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US4842604A Expired / Lapsed US ⏱️ 0.0 years remaining

Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics

Assignee: Dow Chemical Co
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Filing: 1987-06-01
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Granted: 1989-06-27
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Expires: 2007-06-01
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Abstract

Abstract A process for the prosthetic supplementation or replacement of hard tissue. In the process an anatomically-shaped form is molded by or a prosthetic device is coated with a composite material containing unsintered calcium phosphate biomaterial, a synthetic biodegradable polymer, and optionally, a pore-forming agent.

Inventors

  • 👤 Linneaus C. Dorman
  • 👤 Paul A. Meyers

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:37
CPC Classifications
C; C08; C08G; C08G69/00; C08G69/02; C08G69/08; C08G69/10; A; A61; A61L; A61L27/00; A61L27/40; A61L27/44; A61L27/46; A61L27/50; A61L27/56; A61F; A61F2210/00; A61F2210/0004

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 118 words
A process for the prosthetic supplementation or replacement of hard tissue which comprises molding into an anatomically-shaped form a composite material containing from about 25 to about 75 percent by weight of an unsintered calcium phosphate biomaterial and about 75 to about 25 percent by weight of synthetic biodegradable polymer selected from the group consisting of a polyester of glycolic acid, a polyester of lactic acid, polyhydroxybutyrate, an α-amino acid polymer, and mixtures thereof, said composite material also containing from about 5 to about 30 percent by weight of a pore-forming agent (based on the total weight of the composite material plus the pore-forming agent); and implanting said anatomically-shaped form into an animal or human in need thereof.
Claim 2
Dependent Claim 118 words
A process for the prosthetic supplementation or replacement of hard tissue which comprises molding into an anatomically-shaped form a composite material containing from about 25 to about 75 percent by weight of an unsintered calcium phosphate biomaterial and about 75 to about 25 percent by weight of synthetic biodegradable polymer selected from the group consisting of a polyester of glycolic acid, a polyester of lactic acid, polyhydroxybutyrate, an α-amino acid polymer, and mixtures thereof, said composite material also containing from about 5 to about 30 percent by weight of a pore-forming agent (based on the total weight of the composite material plus the pore-forming agent); and implanting said anatomically-shaped form into an animal or human in need thereof.
Claim 3
Dependent Claim 15 words
The process of claim 1 wherein said synthetic biodegradable polymer is an α-amino acid polymer.
Claim 4
Dependent Claim 35 words
The process of claim 2 wherein said composite material contains from about 10 to about 20 percent by weight of a pore-forming agent (based on the total weight of the composite material plus pore-forming agent).
Claim 5
Dependent Claim 28 words
The process of claim 2 wherein the α-amino acid polymer is a glutamic acid-γ-ester polymer and the unsintered calcium phosphate biomaterial is unsintered hydroxyapatite or unsintered tricalcium phosphate.
Claim 6
Dependent Claim 13 words
The process of claim 4 wherein the glutamic acid-γ-ester is glutamic acid-γ-methyl ester.
Claim 7
Dependent Claim 13 words
The process of claim 4 wherein the glutamic acid-γ-ester is glutamic acid-γ-benzyl ester.
Claim 8
Dependent Claim 25 words
The process of claim 5 wherein said composite material contains from about 40 to about 60 percent by weight of said unsintered calcium phosphate biomaterial.
Claim 9
Dependent Claim 25 words
The process of claim 6 wherein said composite material contains from about 40 to about 60 percent by weight of said unsintered calcium phosphate biomaterial.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-06-26 1992-12-26 1993-06-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-06-26 1996-12-26 1997-06-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-06-26 2000-12-26 2001-06-27 $7700.00 Window Closed / Lapsed

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