US4411795A
Expired / Lapsed
US
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Particle adsorption
Assignee: Baxter International Inc
•
Filing: 1981-02-26
•
Granted: 1983-10-25
•
Expires: 2001-02-26
Abstract
Abstract Lipin particles are removed from aqueous suspension by adsorption on hydrophilic macromolecules substituted with pendant hydrophobic groups. Particularly beneficial results are achieved by use of pendant hydrophobes linked by strongly ionogenic groups to water insoluble carriers.
Inventors
- 👤 Wayne P. Olson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 23:37
CPC Classifications
C; C02; C02F; C02F1/00; C02F1/28; C02F1/285; A; A61; A61L; A61L2/00; A61L2/02; A61L2/022; A61L2/16; A61L9/00; A61L9/16; B; B01; B01D; B01D15/00; C12; C12N; C12N1/00; C12N1/02; C12N11/00; C12N11/02; C12N11/08; C12N11/089; C12N11/096; A61L2103/00; A61L2103/05; B01D15/08; B01D15/26; B01D15/32; B01D15/325; B01D15/327; Y; Y10; Y10S; Y10S210/00; Y10S210/902; Y10S210/908
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
67 words
A method for removing lipin particles from suspension in a fluid, comprising contacting the suspension with an adsorbent composition having the formula [(Y).sub.e B].sub.d Z wherein Y is a hydrophobic ligand, B is a strong ionogenic group, Z is a water insoluble carrier, e is an integer and d is greater than 2 under conditions to adsorb the particles, followed by separating the compositions from the fluid.
Claim 2
Independent Claim
67 words
A method for removing lipin particles from suspension in a fluid, comprising contacting the suspension with an adsorbent composition having the formula [(Y).sub.e B].sub.d Z wherein Y is a hydrophobic ligand, B is a strong ionogenic group, Z is a water insoluble carrier, e is an integer and d is greater than 2 under conditions to adsorb the particles, followed by separating the compositions from the fluid.
Claim 3
Dependent Claim
90 words
The composition of claim 1 wherein Y is a group having the formula ##STR42## and wherein R is hydrogen, nitro, alkyl, alkyl ether, halogen, monocyclic aromatic hydrocarbon or a carbocycle system; A is a bond, monocyclic aromatic hydrocarbon or carbocycle system; b is an integer; J is oxygen, sulfur or a bond; and n and y are zero or an integer; with the proviso that where A is a bond and R is hydrogen, nitro or halogen then the sum of n and y is an integer greater than 5.
Claim 4
Dependent Claim
17 words
The composition of claim 2 wherein R is alkyl having about from 1 to 6 carbon atoms.
Claim 5
Dependent Claim
29 words
The composition of claim 2 wherein the sum of n and y is 8, R is hydrogen, J and A are bonds and e and b are both 1.
Claim 6
Dependent Claim
18 words
The composition of claim 1 wherein Y is normal alkyl having from 6 to about 20 carbon atoms.
Claim 7
Dependent Claim
9 words
The conposition of claim 1 wherein Y is phenyl.
Claim 8
Dependent Claim
12 words
The composition of claim 1 wherein B and Z together are hydrophilic.
Claim 9
Dependent Claim
11 words
The composition of claim 1 wherein Z is an organic polymer.
Claim 10
Dependent Claim
20 words
The composition of claim 8 wherein the polymer contains strong ionogenic groups which are not substituted with a hydrophobic ligand.
Claim 11
Dependent Claim
13 words
The composition of claim 9 wherein the group is sulfonyl or quaternary amino.
Claim 12
Dependent Claim
9 words
The composition of claim 1 wherein Z is inorganic.
Claim 13
Dependent Claim
9 words
The composition of claim 11 wherein Z is glass.
Claim 14
Dependent Claim
9 words
The composition of claim 1 wherein e is 1.
Claim 15
Dependent Claim
12 words
The method of claim 1 wherein the fluid is an aqueous ligand.
Claim 16
Dependent Claim
17 words
The method of claim 14 wherein the liquid has an ionic strength of less than about 0.1.
Claim 17
Dependent Claim
16 words
The method of claim 15 wherein the liquid contains about from 1 to 30% protein (w/v).
Claim 18
Dependent Claim
10 words
The method of claim 14 wherein the particles are viruses.
Claim 19
Dependent Claim
12 words
The method of claim 1 wherein the adsorbent is a formed article.
Claim 20
Dependent Claim
13 words
The method of claim 1 wherein the adsorbent is woven or a membrane.
Claim 21
Dependent Claim
12 words
The method of claim 1 wherein the adsorbent is a fibrous mass.
Claim 22
Dependent Claim
28 words
The method of claim 1 wherein Z is an organic polymer and d ranges about from 0.5 to 0.1 times the number of monomer units constituting the polymer.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-10-24 | 1987-04-25 | 1987-10-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-10-24 | 1991-04-25 | 1991-10-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-10-24 | 1995-04-25 | 1995-10-25 | $7700.00 | Window Closed / Lapsed |