US6005162A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Methods of repairing bone
Assignee: Norian Corp
•
Filing: 1997-01-29
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Granted: 1999-12-21
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Expires: 2017-01-29
Abstract
Abstract Methods are provided for repairing bone. In the subject methods, a flowable composition capable of setting under physiological conditions into an physiologically acceptable calcium phosphate mineral is administered to a bone repair site. Following administration, the composition is allowed to harden, whereby the bone is repaired.
Inventors
- 👤 Brent R. Constantz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 08:25
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/02; A61L27/12; A61K; A61K6/00; A61K6/30; A61K6/50; A61K6/54; A61K6/80; A61K6/831; A61K6/838; A61K6/849; A61K6/864; A61K6/873; A61K6/876; A61L24/00; A61L24/02; A61F; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293; A61L2430/00; A61L2430/38; Y; Y10; Y10S; Y10S623/00; Y10S623/92; Y10S623/923
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
96 words
A method of repairing bone comprising a defect at a bone repair site, said method comprising: (a) combining phosphoric acid substantially free of uncombined water, a a calcium source and neutralizing anions including at least one of carbonate, phosphate and hydroxide in an amount sufficient to substantially neutralize said phosphoric acid with water such that a flowable composition capable of setting into a calcium phosphate mineral is produced; (b) administering said flowable composition to said bone repair site; and (c) allowing said flowable composition to set into said calcium phosphate mineral; whereby said bone is repaired.
Claim 2
Independent Claim
96 words
A method of repairing bone comprising a defect at a bone repair site, said method comprising: (a) combining phosphoric acid substantially free of uncombined water, a a calcium source and neutralizing anions including at least one of carbonate, phosphate and hydroxide in an amount sufficient to substantially neutralize said phosphoric acid with water such that a flowable composition capable of setting into a calcium phosphate mineral is produced; (b) administering said flowable composition to said bone repair site; and (c) allowing said flowable composition to set into said calcium phosphate mineral; whereby said bone is repaired.
Claim 3
Dependent Claim
24 words
The method according to claim 1, wherein said defect is weak osteoporotic bone and said method results in augmentation of said weak osteoporotic bone.
Claim 4
Dependent Claim
20 words
The method according to claim 1, wherein said defect is a void and said method results in filling said void.
Claim 5
Dependent Claim
22 words
The method according to claim 1, wherein said defect requires implantation of a prosthetic implant and said composition is said prosthetic implant.
Claim 6
Dependent Claim
20 words
The method according to claim 1, wherein said defect comprises a hardware removal site and said composition fills said site.
Claim 7
Dependent Claim
36 words
The method according to claim 1, wherein said method of repairing bone comprises adhering a structure to a surface of said bone and said composition is applied to said surface to hold said structure in place.
Claim 8
Dependent Claim
18 words
The method according to claim 1, wherein said bone repair site is the intermedullary canal of a femur.
Claim 9
Independent Claim
107 words
A method of repairing bone comprising a defect requiring the adherence of a structure to the surface of said bone, said method comprising: (a) combining phosphoric acid substantially free of uncombined water, a calcium source and neutralizing anions including at least one of carbonate, phosphate and hydroxide in an amount sufficient to substantially neutralize said phosphoric acid with water such that a flowable composition capable of setting into a calcium phosphate mineral is produced; (b) administering said flowable composition to said defect; (c) adjoining said structure to said surface; and (c) allowing said flowable composition to set into said calcium phosphate mineral; whereby said bone is repaired.
Claim 10
Independent Claim
107 words
A method of repairing bone comprising a defect requiring the adherence of a structure to the surface of said bone, said method comprising: (a) combining phosphoric acid substantially free of uncombined water, a calcium source and neutralizing anions including at least one of carbonate, phosphate and hydroxide in an amount sufficient to substantially neutralize said phosphoric acid with water such that a flowable composition capable of setting into a calcium phosphate mineral is produced; (b) administering said flowable composition to said defect; (c) adjoining said structure to said surface; and (c) allowing said flowable composition to set into said calcium phosphate mineral; whereby said bone is repaired.
Claim 11
Dependent Claim
13 words
The method according to claim 8, wherein said flowable composition is a paste.
Claim 12
Dependent Claim
12 words
The method according to claim 9, wherein said defect is a fracture.
Claim 13
Independent Claim
109 words
A method of repairing a bone fracture requiring the adherence of a structure to the surface of a fractured bone, said method comprising: (a) combining phosphoric acid substantially free of uncombined water, a calcium source and neutralizing anions including at least one of carbonate, phosphate and hydroxide in an amount sufficient to substantially neutralize said phosphoric acid with water such that a flowable composition capable of setting into a calcium phosphate mineral is produced; (b) administering said flowable composition to said bone fracture; (c) adjoining said structure to said surface; and (c) allowing said flowable composition to set into said calcium phosphate mineral; whereby said bone fracture is repaired.
Claim 14
Independent Claim
109 words
A method of repairing a bone fracture requiring the adherence of a structure to the surface of a fractured bone, said method comprising: (a) combining phosphoric acid substantially free of uncombined water, a calcium source and neutralizing anions including at least one of carbonate, phosphate and hydroxide in an amount sufficient to substantially neutralize said phosphoric acid with water such that a flowable composition capable of setting into a calcium phosphate mineral is produced; (b) administering said flowable composition to said bone fracture; (c) adjoining said structure to said surface; and (c) allowing said flowable composition to set into said calcium phosphate mineral; whereby said bone fracture is repaired.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-12-20 | 2003-06-21 | 2003-12-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-12-20 | 2007-06-21 | 2007-12-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-12-20 | 2011-06-21 | 2011-12-21 | $7700.00 | Window Closed / Lapsed |