EP0543765A1
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EP
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Process for the preparation of calcium phosphate cements and their application as bio-materials
Assignee: Individual
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Filing: 1992-10-30
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Granted: —
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Expires: 2012-10-30
Abstract
Abstract The invention refers to the use of a series of calcium ortophosphate cements as biomaterials, starting from a number of components by grinding and sieving to obtain the adequate grain size, the needed quantity being weighed and the blend of powder products being put into recipients to be shaken up for its homogeneization, the mix being, placed afterwards, in the desired portions, into a container to be supplied to the specialists, together with the capsules containing water or a water solution.
Inventors
- 👤 Maria Gertruda Boltong
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 08:18
CPC Classifications
A; A61; A61L; A61L24/00; A61L24/02; A61F; A61F2/00; A61F2/02; A61F2/28; A61F2002/2817; A61F2/30; A61F2/46; A61F2002/4631
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
73 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, characterized in that the calcium ortophosphate pastes to be used as biomaterials comprise a water mix of at least one reagent selected within the group comprising MCPM, DCP, DCPD, OCP, β-TCP, α-TCP, TTCP, Ca₄Mg₅(PO₄)₃, CaZn₂(PO₄)₂, CaKPO₄, CaNaPO₄, Ca₁₀Na(PO₄)₇, Ca₂PO₄Cl and Ca₁₀(PO₄)₆Cl₂ having said pastes the capacity to harden whenever before its setting they are submitted to 100% relative humidity.
Claim 2
Dependent Claim
73 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, characterized in that the calcium ortophosphate pastes to be used as biomaterials comprise a water mix of at least one reagent selected within the group comprising MCPM, DCP, DCPD, OCP, β-TCP, α-TCP, TTCP, Ca₄Mg₅(PO₄)₃, CaZn₂(PO₄)₂, CaKPO₄, CaNaPO₄, Ca₁₀Na(PO₄)₇, Ca₂PO₄Cl and Ca₁₀(PO₄)₆Cl₂ having said pastes the capacity to harden whenever before its setting they are submitted to 100% relative humidity.
Claim 3
Dependent Claim
48 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, according to claim 1, characterized for using pastes containing as additional reagent one or more compounds from the group Ca(OH)₂, CaO, CaCO₃, MgO, MgCO₃, Mg(OH)₂, ZnO, ZnCO₃ or Na, K, Mg or Zn ortophosphates.
Claim 4
Dependent Claim
50 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, according to the previous claims, characterized for using pastes which additionally contain other components comprising sodium, potassium, magnesium, zinc, calcium, biopolymers, organic or inorganic acids, synthetic polymers and growth factors used as accelerators, retarders o modifiers.
Claim 5
Dependent Claim
44 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, according to the previous claims, characterized for using pastes which further contain one or more crystal seeds choosen from the group DCPD, OCP, PHA, SHA, NCCA, NCDHA or bone minerals.
Claim 6
Dependent Claim
47 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, characterized for using pastes which have been prepared using water solutions or at least one soluble component of sodium, potassium, magnesium, zinc, calcium, biopolymers, organic acids, inorganic acids, synthetic polymers and growth factors.
Claim 7
Dependent Claim
47 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, characterized for using pastes which have been prepared using water solutions or at least one soluble component of sodium, potassium, magnesium, zinc, calcium, biopolymers, organic acids, inorganic acids, synthetic polymers and growth factors.
Claim 8
Dependent Claim
54 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, characterized in that the components which to be used will be previously ground and submitted to sieving to obtain a grain size approximately comprised between 5 and 10 micron and afterwards they will be weighed to prepare the required quantities.
Claim 9
Dependent Claim
54 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, characterized in that the components which to be used will be previously ground and submitted to sieving to obtain a grain size approximately comprised between 5 and 10 micron and afterwards they will be weighed to prepare the required quantities.
Claim 10
Dependent Claim
90 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, according to claim 6, characterized in that the blend of powder products will be put into a recipient to be filled up to 25,% of its capacity, submitting the same to rotation on a roller for 60 minutes or to vigorous shaking for 5 minutes, putting the blend afterwards in portions, adequate to its application, into a bottle for its supply to the specialists, together with capsules containing the desired quantity of water or water solution.
Claim 11
Dependent Claim
69 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, according the claims 5 and 6, characterized in that the bottles will be sterilized as well as the capsules and its contents, with the possibility of supplying to health centers the powder product and the liquid together on a glass plate or on tiles, to be mixed for a few minutes to obtain a paste.
Claim 12
Dependent Claim
63 words
- Process for the preparation of calcium phosphate cements and its application as bio-materials, according to claim 8, characterized in that in case of injectable cements, the paste which has been obtained will be put into the added injection for its injection to the body and in case of non injectable cements, the paste will be applied by means of a palete knife.
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