US5514092A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Drug delivery and dilatation-drug delivery catheters in a rapid exchange configuration
Assignee: Boston Scientific Scimed Inc
•
Filing: 1994-08-08
•
Granted: 1996-05-07
•
Expires: 2014-08-08
Abstract
Abstract Catheters for drug delivery or for both dilatation and drug delivery are provided with a guide wire lumen terminating within the catheter shaft and having an opening through the catheter shaft to enable a guide wire to exit the catheter shaft substantially distal to the proximal end of the catheter. In one embodiment, drug delivery ports are provided between occlusion balloons. In another embodiment, a dilatation balloon is also provided between the occlusion balloons. In another embodiment, a double layered balloon is provided to simultaneously dilatate the stenosis and deliver medication to the site. Alternatively, a balloon can be provided which only delivers medication.
Inventors
- 👤 Michael R. Forman
- 👤 Lori L. Stowell
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:12
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/104; A61M25/1011; A61M25/0043; A61M2025/0063; A61M25/01; A61M2025/0183; A61M2025/1013; A61M2025/1043; A61M2025/105; A61M2025/1052; A61M2025/1079
Claims Analysis
Total Claims: 40
Claim 1
Independent Claim
105 words
A drug delivery catheter comprising: a catheter shaft comprising a proximal end, a distal end, at least one drug delivery port proximate the distal end and at least one drug delivery lumen for providing a drug to the drug delivery port, the at least one drug delivery lumen in fluid communication with the proximal end, the catheter shaft further comprising a guide wire lumen extending from the distal end of the catheter shaft to a terminus within the catheter shaft, the terminus being proximal to the drug delivery port, and defining an opening proximate the terminus for the guide wire to exit the catheter shaft.
Claim 2
Dependent Claim
105 words
A drug delivery catheter comprising: a catheter shaft comprising a proximal end, a distal end, at least one drug delivery port proximate the distal end and at least one drug delivery lumen for providing a drug to the drug delivery port, the at least one drug delivery lumen in fluid communication with the proximal end, the catheter shaft further comprising a guide wire lumen extending from the distal end of the catheter shaft to a terminus within the catheter shaft, the terminus being proximal to the drug delivery port, and defining an opening proximate the terminus for the guide wire to exit the catheter shaft.
Claim 3
Dependent Claim
31 words
The drug delivery catheter of claim 1, further comprising a first occlusion balloon distal to the drug delivery port, and an inflation lumen in fluid communication with the first occlusion balloon.
Claim 4
Dependent Claim
34 words
The drug delivery catheter of claim 2, further comprising a second occlusion balloon proximal to the drug delivery port, wherein the terminus of the guide wire lumen is proximal to the second occlusion balloon.
Claim 5
Dependent Claim
22 words
The drug delivery catheter of claim 3, wherein the inflation lumen is in fluid communication with the first and second occlusion balloons.
Claim 6
Dependent Claim
24 words
The drug delivery catheter of claim 1, wherein there are a plurality of drug delivery ports in fluid communication with the drug delivery lumen.
Claim 7
Dependent Claim
16 words
The drug delivery catheter of claim 1, further comprising a lubricous coating on the catheter shaft.
Claim 8
Dependent Claim
20 words
The drug delivery catheter of claim 3, further comprising a lubricous coating on the catheter shaft and the occlusion balloons.
Claim 9
Dependent Claim
15 words
The drug delivery catheter of claim 3, wherein the occlusion balloons comprise inflatable plastic tubes.
Claim 10
Dependent Claim
14 words
The drug delivery catheter of claim 3, wherein the occlusion balloons are blow molded.
Claim 11
Dependent Claim
25 words
The drug delivery catheter of claim 2, further comprising perfusion means for allowing blood to flow through at least a portion of the catheter shaft.
Claim 12
Dependent Claim
18 words
The drug delivery catheter of claim 3, further comprising an additional lumen in the catheter shaft for perfusion.
Claim 13
Dependent Claim
31 words
The drug delivery catheter of claim 11, further comprising at least one opening in a wall of the catheter shaft, proximal the occlusion balloons, in fluid communication with the additional lumen.
Claim 14
Dependent Claim
23 words
The drug delivery catheter of claim 1, further comprising a dilatation balloon and a dilatation lumen in fluid communication with the dilatation balloon.
Claim 15
Dependent Claim
33 words
The drug delivery catheter of claim 3, further comprising a dilatation balloon and a dilatation lumen in fluid communication with the dilatation balloon, wherein the dilatation balloon is located between the occlusion balloons.
Claim 16
Dependent Claim
20 words
The drug delivery catheter of claim 1, wherein the guide wire lumen is proximate the periphery of the catheter shaft.
Claim 17
Dependent Claim
16 words
The drug delivery catheter of claim 12, wherein the additional lumen has a tapered distal end.
Claim 18
Dependent Claim
32 words
The drug delivery catheter of claim 2, further comprising at least one port through the catheter shaft to the guide wire lumen, to enable perfusion of blood through the guide wire lumen.
Claim 19
Dependent Claim
84 words
A catheter comprising: a catheter shaft having a distal portion, a distal end, and a proximal end; means for conveying a drug to an exterior of the catheter; means for delivering the drug from the proximal end to the means for conveying; and means for receiving a guide wire within the distal portion of the catheter shaft, the means for receiving including a means for the guide wire to exit the distal portion of the catheter shaft to the exterior of the catheter shaft.
Claim 20
Dependent Claim
84 words
A catheter comprising: a catheter shaft having a distal portion, a distal end, and a proximal end; means for conveying a drug to an exterior of the catheter; means for delivering the drug from the proximal end to the means for conveying; and means for receiving a guide wire within the distal portion of the catheter shaft, the means for receiving including a means for the guide wire to exit the distal portion of the catheter shaft to the exterior of the catheter shaft.
Claim 21
Dependent Claim
31 words
The catheter of claim 18, wherein the means for conveying comprises at least one port in the distal portion of the catheter shaft, in fluid communication with the means for delivering.
Claim 22
Dependent Claim
55 words
The catheter of claim 18, wherein the means for conveying is a balloon attached to the distal portion of the catheter shaft, wherein the balloon defines a plurality of openings for enabling the drug to exit the balloon to the exterior of the catheter, the balloon being in fluid communication with the means for delivering.
Claim 23
Dependent Claim
17 words
The catheter of claim 20, wherein the balloon is adapted to dilatate a stenosis while conveying drugs.
Claim 24
Dependent Claim
63 words
The catheter of claim 21, wherein the balloon comprises an outer and an inner layer, the plurality of openings being in the outer layer, the outer and inner layer defining a region in fluid communication with the means for delivering, and the inner layer having an interior region, the catheter shaft further comprising a means for delivering inflation fluid to the interior region.
Claim 25
Dependent Claim
90 words
The catheter of claim 18, wherein the catheter shaft has a proximal end and the means for receiving the guide wire comprises a lumen within the distal portion of the catheter shaft, the lumen having a first end proximate the distal end of the catheter shaft and open to the exterior of the catheter, the lumen terminating at its proximal end substantially distal of the proximal end of the catheter shaft in a aperture open to the exterior of the catheter, the aperture being proximal to the means for conveying.
Claim 26
Dependent Claim
9 words
The catheter of claim 18, further comprising perfusion means.
Claim 27
Dependent Claim
9 words
The catheter of claim 18, further comprising occlusion means.
Claim 28
Dependent Claim
233 words
A dilatation-drug delivery catheter comprising: a catheter shaft comprising a distal portion, a distal end and a proximal end; a dilatation balloon attached to the distal portion of the catheter shaft; a first occlusion balloon attached to the catheter shaft at a location distal to the dilatation balloon and a second occlusion balloon attached to the catheter shaft at a location proximal to the dilatation balloon; the catheter shaft further comprising at least one drug delivery port in the distal portion of the catheter shaft, between the dilatation balloon and at least one of the occlusion balloons, at least one dilatation lumen in fluid communication with the dilatation balloon, at least one inflation lumen in fluid communication with the occlusion balloons, at least one drug delivery lumen fluidly communicating between the drug delivery port and the proximal end, and a guide wire lumen in the distal portion of the catheter shaft, the guide wire lumen having a first opening to an exterior of the catheter shaft at the distal end of the catheter shaft and a second opening to the exterior of the catheter shaft in the distal portion of the catheter shaft, proximal to the second occlusion balloon and substantially distal to the proximal end of the catheter shaft, such that a guide wire can enter the catheter shaft through the first opening and exit the catheter shaft through the second opening.
Claim 29
Dependent Claim
233 words
A dilatation-drug delivery catheter comprising: a catheter shaft comprising a distal portion, a distal end and a proximal end; a dilatation balloon attached to the distal portion of the catheter shaft; a first occlusion balloon attached to the catheter shaft at a location distal to the dilatation balloon and a second occlusion balloon attached to the catheter shaft at a location proximal to the dilatation balloon; the catheter shaft further comprising at least one drug delivery port in the distal portion of the catheter shaft, between the dilatation balloon and at least one of the occlusion balloons, at least one dilatation lumen in fluid communication with the dilatation balloon, at least one inflation lumen in fluid communication with the occlusion balloons, at least one drug delivery lumen fluidly communicating between the drug delivery port and the proximal end, and a guide wire lumen in the distal portion of the catheter shaft, the guide wire lumen having a first opening to an exterior of the catheter shaft at the distal end of the catheter shaft and a second opening to the exterior of the catheter shaft in the distal portion of the catheter shaft, proximal to the second occlusion balloon and substantially distal to the proximal end of the catheter shaft, such that a guide wire can enter the catheter shaft through the first opening and exit the catheter shaft through the second opening.
Claim 30
Dependent Claim
11 words
The catheter of claim 26, wherein the catheter shaft is integral.
Claim 31
Dependent Claim
15 words
The catheter of claim 26, wherein the catheter shaft comprises tubes which define the lumens.
Claim 32
Dependent Claim
199 words
A dilatation-drug delivery catheter comprising: a catheter shaft comprising a distal portion, a distal end and a proximal end; a dilatation balloon attached to the distal portion of the catheter shaft, the dilatation balloon having an outer and an inner layer wherein the inner layer defines an inner region proximate the catheter shaft and the outer and inner layers define an outer region, and the outer layer comprises a plurality of openings; the catheter shaft further comprising a first lumen fluidly communicating between the outer region and the proximal end, and a second lumen in fluid communication with the inner region, and a third lumen in the distal portion of the catheter shaft for receiving a guide wire, the third lumen having a first opening to an exterior of the catheter shaft at the distal end of the catheter shaft and a second opening to the exterior of the catheter shaft in the distal portion of the catheter shaft, proximal to the dilatation balloon and substantially distal to the proximal end of the catheter shaft, such that the guide wire can enter the catheter shaft through the first opening and can exit the catheter shaft through the second opening.
Claim 33
Dependent Claim
199 words
A dilatation-drug delivery catheter comprising: a catheter shaft comprising a distal portion, a distal end and a proximal end; a dilatation balloon attached to the distal portion of the catheter shaft, the dilatation balloon having an outer and an inner layer wherein the inner layer defines an inner region proximate the catheter shaft and the outer and inner layers define an outer region, and the outer layer comprises a plurality of openings; the catheter shaft further comprising a first lumen fluidly communicating between the outer region and the proximal end, and a second lumen in fluid communication with the inner region, and a third lumen in the distal portion of the catheter shaft for receiving a guide wire, the third lumen having a first opening to an exterior of the catheter shaft at the distal end of the catheter shaft and a second opening to the exterior of the catheter shaft in the distal portion of the catheter shaft, proximal to the dilatation balloon and substantially distal to the proximal end of the catheter shaft, such that the guide wire can enter the catheter shaft through the first opening and can exit the catheter shaft through the second opening.
Claim 34
Dependent Claim
25 words
The catheter of claim 29, wherein the first lumen is adapted to deliver a drug and the second lumen is adapted to deliver inflation fluid.
Claim 35
Dependent Claim
162 words
A drug delivery catheter comprising: a catheter shaft having a distal portion, a distal end and a proximal end; a drug delivery balloon attached to the distal portion of the catheter shaft, the drug delivery balloon including a plurality of ports extending through the balloon; the catheter shaft further comprising at least one delivery lumen fluidly communicating between the drug delivery balloon and the proximal end, and a lumen in the distal portion of the catheter shaft for receiving a guide wire, the lumen having a first opening to the exterior of the catheter shaft at the distal end of the catheter shaft and a second opening to the exterior of the catheter shaft in the distal portion of the catheter shaft, proximal to the drug delivery balloon and substantially distal to the proximal end of the catheter shaft, such that the guide wire can enter the catheter shaft through the first opening and exit the catheter shaft through the second opening.
Claim 36
Dependent Claim
162 words
A drug delivery catheter comprising: a catheter shaft having a distal portion, a distal end and a proximal end; a drug delivery balloon attached to the distal portion of the catheter shaft, the drug delivery balloon including a plurality of ports extending through the balloon; the catheter shaft further comprising at least one delivery lumen fluidly communicating between the drug delivery balloon and the proximal end, and a lumen in the distal portion of the catheter shaft for receiving a guide wire, the lumen having a first opening to the exterior of the catheter shaft at the distal end of the catheter shaft and a second opening to the exterior of the catheter shaft in the distal portion of the catheter shaft, proximal to the drug delivery balloon and substantially distal to the proximal end of the catheter shaft, such that the guide wire can enter the catheter shaft through the first opening and exit the catheter shaft through the second opening.
Claim 37
Dependent Claim
10 words
The catheter of claim 31, further comprising a perfusion lumen.
Claim 38
Dependent Claim
26 words
The catheter of claim 32, wherein the perfusion lumen extends from the distal end of the catheter shaft to the proximal end of the catheter shaft.
Claim 39
Dependent Claim
61 words
The catheter of claim 32, wherein the perfusion lumen extends from the distal end of the catheter shaft to a terminus proximal to the drug delivery balloon, the catheter shaft further comprising at least one port proximate the terminus of the perfusion lumen and extending through the catheter shaft to the perfusion lumen, to enable blood to enter the perfusion lumen.
Claim 40
Dependent Claim
14 words
The catheter of claim 34, wherein the perfusion lumen has a tapered distal end.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-05-07 | 1999-11-06 | 2000-05-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-05-07 | 2003-11-06 | 2004-05-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-05-07 | 2007-11-06 | 2008-05-07 | $7700.00 | Window Closed / Lapsed |