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US5272012A Expired / Lapsed US ⏱️ 0.0 years remaining

Medical apparatus having protective, lubricious coating

Assignee: Medtronic Vascular Inc
•
Filing: 1992-01-29
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Granted: 1993-12-21
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Expires: 2012-01-29
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Abstract

Abstract A method for providing a medical apparatus with a protective, lubricious coating is described. The method comprises providing a coating solution which contains a protective compound such as a urethane, a slip additive such as a siloxane, and optionally, a crosslinking agent for the protective compound such as a polyfunctional aziridine, coating the solution onto a surface of a medical apparatus and allowing the coating to set. The resulting surface coating is lubricious, tough and flexible. The coating is well suited for use with materials used as components of balloon catheters.

Inventors

  • 👤 Margaret P. Opolski

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 07:43
CPC Classifications
A; A61; A61L; A61L29/00; A61L29/08; A61L29/085; C; C08; C08G; C08G18/00; C08G18/06; C08G18/83; C08G18/833; C08J; C08J7/00; C08J7/04; C08J7/0427; C08J7/043; C08J7/046; C08J7/056; C09; C09D; C09D175/00; C09D175/04; C08J2367/00; C08J2367/02; Y; Y10; Y10T; Y10T428/00; Y10T428/31504; Y10T428/31551; Y10T428/31565; Y10T428/31652; Y10T428/31663

Claims Analysis

Total Claims: 79
Claim 1
Independent Claim 84 words
A method for providing a protective, lubricious coating on a surface of a medical apparatus, the method comprising: applying a coating solution to a surface of the medical apparatus such that a protective, lubricious layer is formed upon the apparatus surface, wherein the coating solution comprises a protective compound and a slip additive and the formed layer contains the protective compound as a binder to maintain domains of the slip additive such that lubricating amounts of the slip additive are exposed to provide lubricity.
Claim 2
Independent Claim 84 words
A method for providing a protective, lubricious coating on a surface of a medical apparatus, the method comprising: applying a coating solution to a surface of the medical apparatus such that a protective, lubricious layer is formed upon the apparatus surface, wherein the coating solution comprises a protective compound and a slip additive and the formed layer contains the protective compound as a binder to maintain domains of the slip additive such that lubricating amounts of the slip additive are exposed to provide lubricity.
Claim 3
Dependent Claim 24 words
A method as claimed in claim 1 wherein the coating solution in the applying step further comprises a crosslinking agent for the protective compound.
Claim 4
Dependent Claim 21 words
A method as claimed in claim 2 wherein the crosslinking agent enhances the adhesion of the coating to the medical apparatus.
Claim 5
Dependent Claim 13 words
A method as claimed in claim 2 wherein the crosslinking agent is aziridine.
Claim 6
Dependent Claim 14 words
A method as claimed in claim 2 wherein the crosslinking agent is a carbodiimide.
Claim 7
Dependent Claim 21 words
A method as claimed in claim 1 wherein in the applying step, the protective compound in the formed layer is crosslinked.
Claim 8
Dependent Claim 24 words
A method as claimed in claim 6 wherein the protective compound is crosslinked to itself and to functional moieties derived from the medical apparatus.
Claim 9
Dependent Claim 26 words
A method as claimed in claim 7 wherein the functional moieties derived from the medical apparatus are from the material from which the apparatus is made.
Claim 10
Dependent Claim 21 words
A method as claimed in claim 7 wherein the functional moieties derived from the medical apparatus are from a primer layer.
Claim 11
Dependent Claim 21 words
A method as claimed in claim 1 wherein in the applying step, the protective compound is dispersed in an aqueous solution.
Claim 12
Dependent Claim 27 words
A method as claimed in claim 10 wherein the aqueous solution of the protective compound has a solids content from about 2% to about 80% by weight.
Claim 13
Dependent Claim 20 words
A method as claimed in claim 11 wherein the solids content is from about 10 to about 50 weight percent.
Claim 14
Independent Claim 20 words
A method as claimed in claims 1 or 10 wherein in the applying step, the protective compound is a urethane.
Claim 15
Independent Claim 20 words
A method as claimed in claims 1 or 10 wherein in the applying step, the protective compound is an acrylic.
Claim 16
Dependent Claim 23 words
A method as claimed in claim 13 wherein the urethane is dispersed in an aqueous solution containing triethylamine and N methyl 2 pyrrolidone.
Claim 17
Dependent Claim 17 words
A method as claimed in claim 1 wherein the slip additive in the applying step is hydrophobic.
Claim 18
Dependent Claim 17 words
A method as claimed in claim 1 wherein the slip additive in the applying step is hydrophilic.
Claim 19
Dependent Claim 16 words
A method as claimed in claim 1 wherein the slip additive is a silicon containing compound.
Claim 20
Dependent Claim 14 words
A method as claimed in claim 18 wherein the slip additive is a silicone.
Claim 21
Dependent Claim 14 words
A method as claimed in claim 18 wherein the slip additive is a siloxane.
Claim 22
Dependent Claim 13 words
A method as claimed in claim 20 wherein the siloxane is dimethyl siloxane.
Claim 23
Dependent Claim 16 words
A method as claimed in claim 17 wherein the slip additive is a polyvinyl pyrrolidone copolymer.
Claim 24
Dependent Claim 22 words
A method as claimed in claim 1 wherein the slip additive in the applying step is in the form of an emulsion.
Claim 25
Dependent Claim 19 words
A method as claimed in claim 23 wherein the coating solution in the applying step further comprises a pigment.
Claim 26
Dependent Claim 20 words
A method as claimed in claim 23 wherein the coating solution in the applying step further comprises a radioopaque compound.
Claim 27
Dependent Claim 20 words
A method as claimed in claim 23 wherein the coating solution in the applying step further comprises a therapeutic agent.
Claim 28
Dependent Claim 20 words
A method as claimed in claim 23 wherein the coating solution in the applying step further comprises an antimicrobial agent.
Claim 29
Dependent Claim 32 words
A method as claimed in claim 1 wherein the surface of the medical apparatus in the applying step is made of a material having moieties capable of crosslinking with the protective compound.
Claim 30
Dependent Claim 16 words
A method as claimed in claim 28 wherein the moieties capable of crosslinking are carboxyl moieties.
Claim 31
Dependent Claim 23 words
A method as claimed in claim 1 wherein the surface of the medical apparatus in the applying step is made of polyethylene terephthalate.
Claim 32
Dependent Claim 23 words
A method as claimed in claim 1 wherein the surface of the medical apparatus in the applying step is coated with a primer.
Claim 33
Dependent Claim 20 words
A method as claimed in claim 31 wherein the primer has functional moieties capable of crosslinking with the protective compound.
Claim 34
Dependent Claim 14 words
A method as claimed in claim 32 wherein the functional moieties are carboxyl moieties.
Claim 35
Dependent Claim 14 words
A method as claimed in claim 31 wherein the primer comprises ethylene acrylic acid.
Claim 36
Dependent Claim 18 words
A method as claimed in claim 1 wherein the medical apparatus in the applying step comprises a balloon.
Claim 37
Dependent Claim 18 words
A method as claimed in claim 1 wherein the medical apparatus in the applying step comprises a catheter.
Claim 38
Dependent Claim 18 words
A method as claimed in claim 1 wherein the medical apparatus in the applying step comprises a guidewire.
Claim 39
Independent Claim 99 words
A method for providing a protective, lubricious coating on a surface of a medical apparatus, the method comprising: applying a coating solution to a surface of the medical apparatus such that a protective, lubricious layer comprising a binder of a protective, lubricious layer comprising a binder of a protective compound containing domains of a slip additive is formed upon the apparatus surface, wherein the coating solution comprises the protective compound and lubricating amounts of the slip additive and the formed layer contains the protective compound being cross-linked to both itself and to functional moieties derived from the medical apparatus.
Claim 40
Independent Claim 99 words
A method for providing a protective, lubricious coating on a surface of a medical apparatus, the method comprising: applying a coating solution to a surface of the medical apparatus such that a protective, lubricious layer comprising a binder of a protective, lubricious layer comprising a binder of a protective compound containing domains of a slip additive is formed upon the apparatus surface, wherein the coating solution comprises the protective compound and lubricating amounts of the slip additive and the formed layer contains the protective compound being cross-linked to both itself and to functional moieties derived from the medical apparatus.
Claim 41
Dependent Claim 24 words
A method as claimed in claim 38 wherein the coating solution in the applying step further comprises a crosslinking agent for the protective compound.
Claim 42
Dependent Claim 21 words
A method as claimed in claim 39 wherein the crosslinking agent enhances the adhesion of the coating to the medical apparatus.
Claim 43
Dependent Claim 13 words
A method as claimed in claim 39 wherein the crosslinking agent is aziridine.
Claim 44
Dependent Claim 13 words
A method as claimed in claim 39 wherein the crosslinking agent is carbodiimide.
Claim 45
Dependent Claim 26 words
A method as claimed in claim 38 wherein the functional moieties derived from the medical apparatus are from the material from which the apparatus is made.
Claim 46
Dependent Claim 21 words
A method as claimed in claim 38 wherein the functional moieties derived from the medical apparatus are from a primer layer.
Claim 47
Dependent Claim 21 words
A method as claimed in claim 38 wherein in the applying step, the protective compound is dispersed in an aqueous solution.
Claim 48
Dependent Claim 18 words
A method as claimed in claim 38 wherein in the applying step, the protective compound is a urethane.
Claim 49
Dependent Claim 17 words
A method as claimed in claim 38 wherein the slip additive in the applying step is hydrophobic.
Claim 50
Dependent Claim 17 words
A method as claimed in claim 38 wherein the slip additive in the applying step is hydrophilic.
Claim 51
Independent Claim 75 words
A method for providing a protective, lubricious coating on surfaces of medical apparatus, the method comprising: applying a coating solution comprising a protective compound and a silicon containing compound to a surface of the medical apparatus; and forming a protective, lubricious layer upon the apparatus surface containing the protective compound and lubricating amounts of the silicon containing compound, the formed layer comprising the protective compound as a binder to maintain domains of the slip additive.
Claim 52
Independent Claim 75 words
A method for providing a protective, lubricious coating on surfaces of medical apparatus, the method comprising: applying a coating solution comprising a protective compound and a silicon containing compound to a surface of the medical apparatus; and forming a protective, lubricious layer upon the apparatus surface containing the protective compound and lubricating amounts of the silicon containing compound, the formed layer comprising the protective compound as a binder to maintain domains of the slip additive.
Claim 53
Dependent Claim 36 words
A medical apparatus having a protective, lubricious surface coating, the coating comprising a binder formed of the protective compound and lubricating amounts of a slip additive such that the binder maintains domains of the slip additive.
Claim 54
Dependent Claim 36 words
A medical apparatus having a protective, lubricious surface coating, the coating comprising a binder formed of the protective compound and lubricating amounts of a slip additive such that the binder maintains domains of the slip additive.
Claim 55
Dependent Claim 15 words
An apparatus as claimed in claim 50 wherein the coating further comprises a crosslinking agent.
Claim 56
Dependent Claim 13 words
An apparatus as claimed in claim 51 wherein the crosslinking agent is aziridine.
Claim 57
Dependent Claim 13 words
An apparatus as claimed in claim 51 wherein the crosslinking agent is carbodiimide.
Claim 58
Dependent Claim 14 words
An apparatus as claimed in claim 50 wherein the protective compound is a urethane.
Claim 59
Dependent Claim 13 words
An apparatus as claimed in claim 50 wherein the slip additive is hydrophobic.
Claim 60
Dependent Claim 13 words
An apparatus as claimed in claim 50 wherein the slip additive is hydrophilic.
Claim 61
Dependent Claim 16 words
An apparatus as claimed in claim 50 wherein the slip additive is a silicone or siloxane.
Claim 62
Dependent Claim 14 words
An apparatus as claimed in claim 57 wherein the slip additive is dimethyl siloxane.
Claim 63
Dependent Claim 19 words
An apparatus as claimed in claim 50 wherein the surface upon which the coating is applied comprises polyethylene terephthalate.
Claim 64
Dependent Claim 11 words
An apparatus as claimed in claim 50 which comprises a balloon.
Claim 65
Dependent Claim 11 words
An apparatus as claimed in claim 50 which comprises a catheter.
Claim 66
Dependent Claim 11 words
An apparatus as claimed in claim 50 which comprises a guidewire.
Claim 67
Dependent Claim 17 words
An apparatus as claimed in claim 50 having a primer layer disposed between the coating and surface.
Claim 68
Dependent Claim 20 words
An apparatus as claimed in claim 63 wherein the primer layer has a functionality suitable for crosslinking with the coating.
Claim 69
Dependent Claim 14 words
An apparatus as claimed in claim 64 wherein the functionality is a carboxyl functionality.
Claim 70
Dependent Claim 15 words
An apparatus as claimed in claim 63 wherein the primer layer comprises ethylene acrylic acid.
Claim 71
Dependent Claim 31 words
An apparatus as claimed in claim 50 wherein the slip additive is hydrophilic and can be bound to both the protective compound and a functionality group derived from the medical apparatus.
Claim 72
Dependent Claim 14 words
An apparatus as claimed in claim 50 wherein the coating further comprises a pigment.
Claim 73
Dependent Claim 15 words
An apparatus as claimed in claim 50 wherein the coating further comprises a radioopaque compound.
Claim 74
Dependent Claim 15 words
An apparatus as claimed in claim 50 wherein the coating further comprises a therapeutic agent.
Claim 75
Dependent Claim 15 words
An apparatus as claimed in claim 50 wherein the coating further comprises an antimicrobial agent.
Claim 76
Dependent Claim 36 words
A medical apparatus having a protective, lubricious surface coating, the coating comprising a protective compound and a slip additive, the protective compound being crosslinked to moieties derived from the medical apparatus thereby strengthening the overall coating.
Claim 77
Dependent Claim 36 words
A medical apparatus having a protective, lubricious surface coating, the coating comprising a protective compound and a slip additive, the protective compound being crosslinked to moieties derived from the medical apparatus thereby strengthening the overall coating.
Claim 78
Dependent Claim 37 words
A medical apparatus having a protective, lubricious surface coating, the coating comprising a binder formed of a protective compound to maintain domains of lubricating amounts of a silicon containing compound for enhancing the lubricity of the coating.
Claim 79
Dependent Claim 37 words
A medical apparatus having a protective, lubricious surface coating, the coating comprising a binder formed of a protective compound to maintain domains of lubricating amounts of a silicon containing compound for enhancing the lubricity of the coating.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-12-20 1997-06-21 1997-12-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-12-20 2001-06-21 2001-12-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-12-20 2005-06-21 2005-12-21 $7700.00 Window Closed / Lapsed

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