Patent US1708731A successfully refreshed from Google Patents.
Patent US6652480B1 successfully refreshed from Google Patents.
US6652480B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Methods for reducing distal embolization
Assignee: Medtronic Vascular Inc
•
Filing: 1999-11-10
•
Granted: 2003-11-25
•
Expires: 2019-11-10
Abstract
Abstract A method for reducing distal embolization during insertion of devices to treat plaque, thrombi and other intravascular occlusions. Using a guide catheter, a guidewire is delivered to a site proximal to the lesion. An aspiration catheter is then introduced over the guidewire, and the two are moved together in a distal to proximal direction across the occlusion. The aspiration catheter is then moved in a proximal to distal direction while continuously aspirating, which prevents embolization of any particles which may be created during the crossing of the guidewire.
Inventors
- 👤 Mir A. Imran
- 👤 Ketan P. Muni
- 👤 Gholam-Reza Zadno-Azizi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:18
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/104; A61B; A61B17/00; A61B17/22; A61B18/00; A61B18/18; A61B18/20; A61B18/22; A61B18/24; A61B18/245; A61B2017/22051; A61B2017/22065; A61B2017/22067; A61B2017/22082; A61B2017/22084; A61M25/01; A61M25/09; A61M2025/09175; A61M2025/09183; A61M25/1011; A61M2025/1015; A61M2025/1043; A61M2025/1052; A61M2025/109; A61M2025/1093
Claims Analysis
Total Claims: 56
Claim 1
Independent Claim
104 words
A method for the evacuation of an occlusive substance from the wall of a blood vessel, comprising: positioning a distal end of a guidewire proximal to at least a portion of the occlusive substance on the wall of said blood vessel; introducing an aspiration catheter over said guidewire; aspirating through the aspiration catheter while crossing the site of the occlusive substance with both the distal end of the guidewire and a distal end of the aspiration catheter; removing the aspiration catheter from the blood vessel; and advancing a therapy catheter into the blood vessel to treat the occlusive substance after removing the aspiration catheter.
Claim 2
Independent Claim
104 words
A method for the evacuation of an occlusive substance from the wall of a blood vessel, comprising: positioning a distal end of a guidewire proximal to at least a portion of the occlusive substance on the wall of said blood vessel; introducing an aspiration catheter over said guidewire; aspirating through the aspiration catheter while crossing the site of the occlusive substance with both the distal end of the guidewire and a distal end of the aspiration catheter; removing the aspiration catheter from the blood vessel; and advancing a therapy catheter into the blood vessel to treat the occlusive substance after removing the aspiration catheter.
Claim 3
Dependent Claim
34 words
The method of claim 1 , further comprising moving the distal end of the aspiration catheter in a distal to proximal direction following delivery of the guidewire across the site of the occlusive substance.
Claim 4
Dependent Claim
24 words
The method of claim 2 , further comprising aspirating while moving the distal end of the aspiration catheter in a distal to proximal direction.
Claim 5
Dependent Claim
26 words
The method of claim 3 , further comprising repeating said crossing while aspirating in both a proximal to distal and in a distal to proximal direction.
Claim 6
Dependent Claim
13 words
The method of claim 1 , wherein said occlusive substance includes an embolus.
Claim 7
Dependent Claim
17 words
The method of claim 1 , wherein said guidewire includes an occlusive device at its distal end.
Claim 8
Dependent Claim
13 words
The method of claim 6 , wherein said occlusive device is a balloon.
Claim 9
Dependent Claim
20 words
The method of claim 6 , further comprising activating said occlusive device to prevent particle migration past said occlusive device.
Claim 10
Dependent Claim
25 words
The method of claim 8 , further comprising delivering a therapy catheter to perform therapy on said occlusive substance following activation of said occlusive device.
Claim 11
Dependent Claim
29 words
The method of claim 9 , wherein said therapy catheter is selected from the group consisting of an angioplasty balloon catheter, a stent delivery catheter and an atherectomy catheter.
Claim 12
Dependent Claim
15 words
The method of claim 1 , wherein said blood vessel is a saphenous vein graft.
Claim 13
Independent Claim
141 words
A method for treatment of an occlusion in a totally occluded blood vessel or partially occluded blood vessel defined by thrombolysis in myocardial infarction (TIMI) flow of 0-1, comprising: delivering a guidewire until its distal end is proximal to the occlusion; delivering an aspiration catheter until a distal end of the aspiration catheter is proximal the occlusion; simultaneously crossing the site of the occlusion in a proximal to distal direction with said distal end of the guidewire and the distal end of the aspiration catheter while aspirating; moving the distal end of the aspiration catheter back across the site of the occlusion in a distal to proximal direction while aspirating; exchanging said guidewire for a guidewire having an occlusive device at its distal end; and positioning the occlusive device at a site distal to the occlusion, and activating said occlusive device.
Claim 14
Independent Claim
141 words
A method for treatment of an occlusion in a totally occluded blood vessel or partially occluded blood vessel defined by thrombolysis in myocardial infarction (TIMI) flow of 0-1, comprising: delivering a guidewire until its distal end is proximal to the occlusion; delivering an aspiration catheter until a distal end of the aspiration catheter is proximal the occlusion; simultaneously crossing the site of the occlusion in a proximal to distal direction with said distal end of the guidewire and the distal end of the aspiration catheter while aspirating; moving the distal end of the aspiration catheter back across the site of the occlusion in a distal to proximal direction while aspirating; exchanging said guidewire for a guidewire having an occlusive device at its distal end; and positioning the occlusive device at a site distal to the occlusion, and activating said occlusive device.
Claim 15
Dependent Claim
18 words
The method of claim 12 , further comprising inserting a therapy catheter to perform therapy on said occlusion.
Claim 16
Dependent Claim
19 words
The method of claim 13 , further comprising introducing said aspiration catheter to remove debris generated during said therapy.
Claim 17
Dependent Claim
15 words
The method of claim 12 , wherein said blood vessel is a saphenous vein graft.
Claim 18
Dependent Claim
12 words
The method of claim 12 , wherein said occlusion includes an embolus.
Claim 19
Dependent Claim
13 words
The method of claim 12 , wherein said occlusive device is a balloon.
Claim 20
Dependent Claim
27 words
The method of claim 12 , further comprising repeating at least once said crossing while aspirating and moving said aspiration catheter in a distal to proximal direction.
Claim 21
Independent Claim
67 words
A method for treatment of an occlusion in a partially occluded blood vessel, comprising: delivering a guidewire having an occlusive device at its distal end until the distal end is distal said occlusion; delivering an aspiration catheter until its distal end is proximal to the occlusion; activating said occlusive device; and crossing the site of the occlusion with the distal end of the aspiration catheter while aspirating.
Claim 22
Independent Claim
67 words
A method for treatment of an occlusion in a partially occluded blood vessel, comprising: delivering a guidewire having an occlusive device at its distal end until the distal end is distal said occlusion; delivering an aspiration catheter until its distal end is proximal to the occlusion; activating said occlusive device; and crossing the site of the occlusion with the distal end of the aspiration catheter while aspirating.
Claim 23
Dependent Claim
27 words
The method of claim 19 , further comprising moving the distal end of the aspiration catheter in a distal to proximal direction across the occlusion while aspirating.
Claim 24
Dependent Claim
24 words
The method of claim 19 , further comprising inserting a therapy catheter to perform therapy on said occlusion following activation of the occlusive device.
Claim 25
Dependent Claim
18 words
The method of claim 21 , further comprising removing the aspiration catheter prior to inserting the therapy catheter.
Claim 26
Dependent Claim
22 words
The method of claim 19 , further comprising introducing said aspiration catheter after performing therapy to remove debris generated during said therapy.
Claim 27
Dependent Claim
15 words
The method of claim 19 , wherein said blood vessel is a saphenous vein graft.
Claim 28
Dependent Claim
12 words
The method of claim 19 , wherein said occlusion includes an embolus.
Claim 29
Dependent Claim
13 words
The method of claim 19 , wherein said occlusive device is a balloon.
Claim 30
Dependent Claim
27 words
The method of claim 20 , further comprising repeating at least once said crossing while aspirating and moving said aspiration catheter in a distal to proximal direction.
Claim 31
Dependent Claim
24 words
The method of claim 21 , wherein said therapy catheter is selected from the group consisting of an atherectomy catheter, stent and balloon catheter.
Claim 32
Dependent Claim
22 words
The method of claim 1 , further comprising exchanging the guidewire for a guidewire having an occlusive device at its distal end.
Claim 33
Dependent Claim
17 words
The method of claim 29 , wherein said exchange occurs prior to removal of the aspiration catheter.
Claim 34
Dependent Claim
16 words
The method of claim 30 , wherein said exchange occurs after removal of the aspiration catheter.
Claim 35
Independent Claim
94 words
A method for treating an occlusive substance from the wall of a blood vessel, comprising: positioning a distal end of a guidewire having an occlusive device at its distal end proximal to at least a portion of the occlusive substance on the wall of said blood vessel; introducing an aspiration catheter over said guidewire; prior to treating the occlusive substance, aspirating through the aspiration catheter while crossing the site of the occlusive substance with both the distal end of the guidewire and a distal end of the aspiration catheter; and treating the occlusive substance.
Claim 36
Independent Claim
94 words
A method for treating an occlusive substance from the wall of a blood vessel, comprising: positioning a distal end of a guidewire having an occlusive device at its distal end proximal to at least a portion of the occlusive substance on the wall of said blood vessel; introducing an aspiration catheter over said guidewire; prior to treating the occlusive substance, aspirating through the aspiration catheter while crossing the site of the occlusive substance with both the distal end of the guidewire and a distal end of the aspiration catheter; and treating the occlusive substance.
Claim 37
Dependent Claim
13 words
The method of claim 32 , wherein said occlusive device is a balloon.
Claim 38
Dependent Claim
24 words
The method of claim 32 , further comprising activating said occlusive device to prevent particle migration past said occlusive device prior to said treatment.
Claim 39
Dependent Claim
25 words
The method of claim 34 , further comprising delivering a therapy catheter to perform therapy on said occlusive substance following activation of said occlusive device.
Claim 40
Dependent Claim
29 words
The method of claim 35 , wherein said therapy catheter is selected from the group consisting of an angioplasty balloon catheter, a stent delivery catheter and an atherectomy catheter.
Claim 41
Dependent Claim
22 words
The method of claim 35 , further comprising removing the aspiration catheter from the blood vessel prior to delivering the therapy catheter.
Claim 42
Independent Claim
122 words
A method for treatment of an occlusion in a blood vessel, comprising: delivering a guidewire having a distal end until the distal end is distal of said occlusion; delivering an aspiration catheter until its distal end is proximal to the occlusion; crossing the site of the occlusion with the distal end of the aspiration catheter while aspirating, wherein the site of the occlusion is crossed with the distal end of the aspiration catheter in a proximal to distal direction while aspirating; crossing the site of the occlusion with the distal end of the aspiration catheter in a distal to proximal direction while aspirating; and repeating said crossing while aspirating in both a proximal to distal and in a distal to proximal direction.
Claim 43
Independent Claim
122 words
A method for treatment of an occlusion in a blood vessel, comprising: delivering a guidewire having a distal end until the distal end is distal of said occlusion; delivering an aspiration catheter until its distal end is proximal to the occlusion; crossing the site of the occlusion with the distal end of the aspiration catheter while aspirating, wherein the site of the occlusion is crossed with the distal end of the aspiration catheter in a proximal to distal direction while aspirating; crossing the site of the occlusion with the distal end of the aspiration catheter in a distal to proximal direction while aspirating; and repeating said crossing while aspirating in both a proximal to distal and in a distal to proximal direction.
Claim 44
Independent Claim
72 words
A method for treatment of an occlusion in a blood vessel, comprising: delivering a guidewire having a distal end until the distal end is distal of said occlusion; delivering an aspiration catheter until its distal end is proximal to the occlusion; crossing the site of the occlusion with the distal end of the aspiration catheter while aspirating; and exchanging the guidewire for a guidewire having an occlusive device on its distal end.
Claim 45
Independent Claim
72 words
A method for treatment of an occlusion in a blood vessel, comprising: delivering a guidewire having a distal end until the distal end is distal of said occlusion; delivering an aspiration catheter until its distal end is proximal to the occlusion; crossing the site of the occlusion with the distal end of the aspiration catheter while aspirating; and exchanging the guidewire for a guidewire having an occlusive device on its distal end.
Claim 46
Dependent Claim
14 words
The method of claim 39 , wherein said exchange occurs through said aspiration catheter.
Claim 47
Independent Claim
79 words
A method for treatment of an occlusion in a blood vessel, comprising: delivering a guidewire having a distal end until the distal end is distal of said occlusion; delivering an aspiration catheter until its distal end is proximal to the occlusion; activating an occlusive device within said vessel to at least partially occlude blood flow; and crossing the site of the occlusion with the distal end of the aspiration catheter while aspirating and while said occlusive device is activated.
Claim 48
Independent Claim
79 words
A method for treatment of an occlusion in a blood vessel, comprising: delivering a guidewire having a distal end until the distal end is distal of said occlusion; delivering an aspiration catheter until its distal end is proximal to the occlusion; activating an occlusive device within said vessel to at least partially occlude blood flow; and crossing the site of the occlusion with the distal end of the aspiration catheter while aspirating and while said occlusive device is activated.
Claim 49
Dependent Claim
30 words
The method of claim 41 , wherein the site of the occlusion is crossed with the distal end of the aspiration catheter in a proximal to distal direction while aspirating.
Claim 50
Dependent Claim
30 words
The method of claim 42 , further comprising crossing the site of the occlusion with the distal end of the aspiration catheter in a distal to proximal direction while aspirating.
Claim 51
Dependent Claim
26 words
The method of claim 43 , further comprising repeating said crossing while aspirating in both a proximal to distal and in a distal to proximal direction.
Claim 52
Dependent Claim
22 words
The method of claim 41 , further comprising exchanging the guidewire for a guidewire having an occlusive device on its distal end.
Claim 53
Dependent Claim
14 words
The method of claim 45 , wherein said exchange occurs through said aspiration catheter.
Claim 54
Dependent Claim
27 words
The method of claim 41 , wherein the guidewire includes said occlusive device on its distal end, and said occlusive device is activated distal to said occlusion.
Claim 55
Dependent Claim
17 words
The method of claim 19 , wherein said aspiration catheter is delivered before activating said occlusive device.
Claim 56
Dependent Claim
35 words
The method of claim 41 , wherein the guidewire is delivered until its distal end is distal of said occlusion prior to delivering the aspiration catheter until its distal end is proximal to the occlusion.
References Cited (Backward Citations)
US3144868A
Cited
US4276874A
Cited
US4299226A
Cited
US4511354A
Cited
US4456011A
Cited
US4573966A
Cited
US4610662A
Cited
US4636195A
Cited
US4445892A
Cited
US4468216A
Cited
US4714460A
Cited
US4692139A
Cited
US4705507A
Cited
US4926858A
Cited
US4790813A
Cited
US4824436A
Cited
US4696668A
Cited
US4781677A
Cited
US4790812A
Cited
US4911163A
Cited
US4723549A
Cited
US4771777A
Cited
US5496346A
Cited
DE3804849A1
Cited
US4832028A
Cited
US5000743A
Cited
US4988356A
Cited
US4794928A
Cited
US5152277A
Cited
WO1989001309A1
Cited
US4921478A
Cited
US4838268A
Cited
US4998917A
Cited
US4950238A
Cited
US5035686A
Cited
US4946466A
Cited
US5460610A
Cited
US5163905A
Cited
US5328471A
Cited
US5135484A
Cited
US5395311A
Cited
US5226889A
Cited
US5320604A
Cited
WO1992021282A1
Cited
US5221270A
Cited
US5645533A
Cited
US5413558A
Cited
US5505702A
Cited
US5458573A
Cited
US5389072A
Cited
US5250060A
Cited
US5415635A
Cited
US5500180A
Cited
US5439000A
Cited
US5281200A
Cited
US5256141A
Cited
US5423744A
Cited
US5320605A
Cited
US5403274A
Cited
US5322508A
Cited
US5342306A
Cited
US5464394A
Cited
US5419774A
Cited
US5405322A
Cited
US5380284A
Cited
WO1995009024A1
Cited
US5634897A
Cited
US5476450A
Cited
US5397307A
Cited
US5458574A
Cited
US5415636A
Cited
US5484412A
Cited
US5478309A
Cited
US5439446A
Cited
WO1996001079A1
Cited
US5514092A
Cited
WO1996015824A1
Cited
US5827229A
Cited
US5833650A
Cited
US5688234A
Cited
US5823996A
Cited
US5868705A
Cited
US6152909A
Cited
WO1997044082A2
Cited
US5833644A
Cited
US6050972A
Cited
US6022336A
Cited
US5662671A
Cited
US5895399A
Cited
US5779721A
Cited
US5879361A
Cited
US5893867A
Cited
WO1998026833A1
Cited
US5968064A
Cited
WO1998038930A1
Cited
US6135991A
Cited
WO1998044982A1
Cited
US5941896A
Cited
WO1999022673A1
Cited
WO1999042059A2
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2006-11-24 | 2007-05-26 | 2007-11-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2010-11-24 | 2011-05-26 | 2011-11-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2014-11-24 | 2015-05-26 | 2015-11-25 | $7700.00 | Window Closed / Lapsed |