Patent US6036631A successfully refreshed from Google Patents.
US6036631A
Expired / Lapsed
US
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Device and method for intracavitary cancer treatment
Assignee: Auslo Research LLC
•
Filing: 1998-03-09
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Granted: 2000-03-14
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Expires: 2018-03-09
Abstract
Abstract A device and method for treatment of cancerous tissue from a body conduit involves insertion into the body conduit of a probe including an energy-emitting element for delivering ionizing energy. The body conduit is dilated to decrease a distance between at least a portion of the body conduit and the cancerous tissue. Ionizing energy is delivered from the energy-emitting element to selectively injure the cancerous tissue, with dilation of the body conduit minimizing the radiation dose delivered to the body conduit for a given radiation dose delivered to the cancerous tissue.
Inventors
- 👤 Jonathan R. McGrath
- 👤 Michael R. Forman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:47
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1014; A61N5/1002; A61N2005/1005
Claims Analysis
Total Claims: 34
Claim 1
Independent Claim
52 words
A device for treatment of cancerous prostate tissue from a urethra, comprising: a probe adapted to be inserted into the urethra, including a retention balloon inflatable in a bladder and an energy-emitting element for delivering ionizing energy to the cancerous prostate tissue; and a dilator at least partially surrounding the energy-emitting element.
Claim 2
Independent Claim
52 words
A device for treatment of cancerous prostate tissue from a urethra, comprising: a probe adapted to be inserted into the urethra, including a retention balloon inflatable in a bladder and an energy-emitting element for delivering ionizing energy to the cancerous prostate tissue; and a dilator at least partially surrounding the energy-emitting element.
Claim 3
Dependent Claim
39 words
The device of claim 1, wherein the probe includes a balloon inflation lumen and the dilator comprises an inflatable dilatation balloon secured to an outer surface of the probe, the balloon being in fluid communication with the inflation lumen.
Claim 4
Dependent Claim
25 words
The device of claim 2, wherein the dilatation balloon is inflatable to a radius of about 0.5 cm from the outer surface of the probe.
Claim 5
Dependent Claim
64 words
The device of claim 2, wherein the energy-emitting element is capable of delivering ionizing radiation having a first intensity at a first radial distance from the probe corresponding to a periphery of the prostate, and having a second intensity of about four times the first intensity at a second radial distance from the probe corresponding to a periphery of the dilatation balloon when inflated.
Claim 6
Dependent Claim
21 words
The device of claim 4, wherein the first intensity is about 15 Gy and the second intensity is about 60 Gy.
Claim 7
Dependent Claim
28 words
The device of claim 2, wherein the dilatation balloon is inflated with a filtering fluid for absorbing selected energies of the ionizing energy delivered by the energy-emitting element.
Claim 8
Dependent Claim
23 words
The device of claim 6, wherein the filtering fluid is imbued with metal particles selected to absorb the selected energies of ionizing radiation.
Claim 9
Dependent Claim
41 words
The device of claim 6, wherein the dilatation balloon has a shape when inflated with a first thickness at an end of the dilatation balloon and a second thickness less than the first thickness at a center of the dilatation balloon.
Claim 10
Dependent Claim
20 words
The device of claim 6, wherein the dilatation balloon includes a plurality of compartments along a length of the probe.
Claim 11
Dependent Claim
32 words
The device of claim 9, wherein each of the plurality of compartments is inflated with a different filtering fluid to absorb different energies of ionizing radiation along the length of the probe.
Claim 12
Dependent Claim
13 words
The device of claim 1, wherein the energy-emitting element comprises a radiation tube.
Claim 13
Dependent Claim
15 words
The device of claim 1, wherein the energy-emitting element comprises at least one radiating seed.
Claim 14
Dependent Claim
18 words
The device of claim 1, wherein the energy-emitting element is movable along an axial length of the probe.
Claim 15
Dependent Claim
27 words
The device of claim 1, further comprising shielding means around the energy-emitting element for producing a radiation pattern that spatially varies along a length of the probe.
Claim 16
Dependent Claim
25 words
The device of claim 14, wherein the shielding means comprises at least one tubular metal shield around at least a portion of the energy-emitting element.
Claim 17
Dependent Claim
22 words
The device of claim 15, wherein the at least one tubular metal shield is located around an outer surface of the probe.
Claim 18
Dependent Claim
23 words
The device of claim 15, wherein the at least one tubular metal shield is composed of a plurality of metals along its length.
Claim 19
Dependent Claim
71 words
The device of claim 14, wherein the probe includes at least one balloon inflation lumen and the shielding means comprises at least one inflatable dilatation balloon secured to an outer surface of the probe, the at least one dilatation balloon being in fluid communication with the at least one inflation lumen and being inflatable with a filtering fluid for absorbing selected energies of the ionizing energy delivered by the energy-emitting element.
Claim 20
Dependent Claim
23 words
The device of claim 18, wherein the filtering fluid is imbued with metal particles selected to absorb the selected energies of ionizing radiation.
Claim 21
Dependent Claim
52 words
The device of claim 18, wherein the at least one inflatable dilatation balloon comprises a compartmentalized balloon having a plurality of compartments and the at least one inflation lumen comprises a plurality of inflation lumens, respective ones of the inflation lumens being in fluid communication with respective compartments of the compartmentalized balloon.
Claim 22
Dependent Claim
30 words
The device of claim 20, wherein each of the plurality of compartments receives a different filtering fluid to absorb differing energies of ionizing radiation along the length of the probe.
Claim 23
Dependent Claim
51 words
The device of claim 18, wherein the at least one inflatable dilatation balloon comprises a plurality of dilatation balloons and the at least one inflation lumen comprises a plurality of inflation lumens, respective ones of the inflation lumens being in fluid communication with respective ones of the plurality of dilatation balloons.
Claim 24
Dependent Claim
31 words
The device of claim 22, wherein each of the plurality of dilatation balloons receives a different filtering fluid to absorb differing energies of ionizing radiation along the length of the probe.
Claim 25
Independent Claim
68 words
A method of treating cancerous prostate tissue comprising: inserting a probe including an energy-emitting element into a urethra, the probe further including an end portion which extends into a bladder; securing the end portion of the probe at a base of the bladder; dilating the urethra; and delivering a predetermined intensity of ionizing energy from the energy-emitting element for a time sufficient to destroy the cancerous prostate tissue.
Claim 26
Independent Claim
68 words
A method of treating cancerous prostate tissue comprising: inserting a probe including an energy-emitting element into a urethra, the probe further including an end portion which extends into a bladder; securing the end portion of the probe at a base of the bladder; dilating the urethra; and delivering a predetermined intensity of ionizing energy from the energy-emitting element for a time sufficient to destroy the cancerous prostate tissue.
Claim 27
Dependent Claim
23 words
The method of claim 24, wherein the step of dilating the urethra comprises increasing a radius of the urethra to about 0.5 cm.
Claim 28
Dependent Claim
24 words
The method of claim 24, wherein the step of dilating the urethra comprises inflating a balloon secured to an outer surface of the probe.
Claim 29
Dependent Claim
24 words
The method of claim 26, wherein the balloon is inflated to a radius of about 0.5 cm from the outer surface of the probe.
Claim 30
Dependent Claim
62 words
The method of claim 26, wherein ionizing energy is delivered from the energy-emitting element with a first intensity at a first radial distance from the probe corresponding to a periphery of the prostate, and with a second intensity of about four times the first intensity at a second radial distance from the probe corresponding to a periphery of the balloon when inflated.
Claim 31
Dependent Claim
18 words
The method of claim 24, further comprising absorbing selected energies of ionizing radiation delivered from the energy-emitting element.
Claim 32
Dependent Claim
21 words
The method of claim 29, wherein the selected energies of ionizing radiation absorbed vary along a length of the energy-emitting element.
Claim 33
Dependent Claim
30 words
The method of claim 24, further comprising shielding at least a portion of the energy-emitting element to produce a radiation pattern that spatially varies along a length of the probe.
Claim 34
Dependent Claim
34 words
The method of claim 24, wherein the step of securing the end portion of the probe at the base of the bladder comprises inflating a retention balloon at the end portion of the probe.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-03-14 | 2003-09-13 | 2004-03-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-03-14 | 2007-09-13 | 2008-03-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-03-14 | 2011-09-13 | 2012-03-14 | $7700.00 | Window Closed / Lapsed |