US5948018A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Expandable supportive endoluminal grafts
Assignee: Lifeport Sciences LLC
•
Filing: 1997-11-07
•
Granted: 1999-09-07
•
Expires: 2017-11-07
Abstract
Abstract An endoluminal graft which is both expandable and supportive is provided either in a longitudinal form or in a bifurcated form. The graft expands between a first diameter and a second, larger diameter. The support component is an expandable stent endoprosthesis. A cover, liner, or a liner, or both a cover and a liner are applied to the endoprosthesis in the form of a stretchable wall material that is porous, elastomeric and biocompatible in order to allow normal cellular invasion upon implantation, without stenosis, when the expandable and supportive graft is at its second diameter. Preferably, the elastomeric wall material is a polycarbonate urethane.
Inventors
- 👤 Jean-Pierre Georges Emile Dereume
- 👤 David C. MacGregor
- 👤 Leonard Pinchuk
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:51
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61F2/07; A61F2/82; A61F2/86; A61F2/90; A61F2/91; A61F2/88; A61F2/885; A61F2/89; A61F2002/065; A61F2002/067; A61F2002/072; A61F2002/075; A61F2/30; A61F2002/30001; A61F2002/30316; A61F2002/30329; A61F2002/826; A61F2220/00; A61F2220/0025; A61F2220/005; A61F2220/0058; A61F2250/00; A61F2250/0014; A61F2250/0039
Claims Analysis
Total Claims: 40
Claim 1
Independent Claim
278 words
An expandable supportive endoluminal graft, comprising: a tubular supporting component with a longitudinal axis, an internal surface disposed toward the longitudinal axis, and an external surface spaced outwardly from and shaped complementarily with said internal surface, said tubular supporting component having a network of land areas with open areas defined therebetween, said tubular supporting component being expandable from a first diameter at which the expandable supportive endoluminal graft is insertable into a body pathway to a second diameter, said second diameter being greater than said first diameter; a stretchable wall of essentially inert biocompatible material, said stretchable wall being applied onto at least one of said internal surface and said external surface of the tubular supporting component, said stretchable wall having a first diameter size when said tubular supporting component is at its said first diameter and a larger second diameter size when said tubular supporting component is at its said second diameter; said stretchable wall is made from a porous elastomeric material that provides a structure which allows normal cellular invasion thereinto from the body pathway when implanted therewithin, said porous elastomeric material being selected from the group consisting of grafts constructed by electrostatic spinning of polymeric fibers, elution of particulate material from polymeric sheeting forming said wall, and solvent phase inversion from polymeric sheeting forming said wall; and said stretchable wall includes a liner over said internal surface of the tubular supporting component, said stretchable wall further including a cover over said external surface of the tubular supporting component, said cover having a longitudinal length less than that of said tubular supporting component in order to thereby define an exposed end of the tubular supporting component.
Claim 2
Dependent Claim
278 words
An expandable supportive endoluminal graft, comprising: a tubular supporting component with a longitudinal axis, an internal surface disposed toward the longitudinal axis, and an external surface spaced outwardly from and shaped complementarily with said internal surface, said tubular supporting component having a network of land areas with open areas defined therebetween, said tubular supporting component being expandable from a first diameter at which the expandable supportive endoluminal graft is insertable into a body pathway to a second diameter, said second diameter being greater than said first diameter; a stretchable wall of essentially inert biocompatible material, said stretchable wall being applied onto at least one of said internal surface and said external surface of the tubular supporting component, said stretchable wall having a first diameter size when said tubular supporting component is at its said first diameter and a larger second diameter size when said tubular supporting component is at its said second diameter; said stretchable wall is made from a porous elastomeric material that provides a structure which allows normal cellular invasion thereinto from the body pathway when implanted therewithin, said porous elastomeric material being selected from the group consisting of grafts constructed by electrostatic spinning of polymeric fibers, elution of particulate material from polymeric sheeting forming said wall, and solvent phase inversion from polymeric sheeting forming said wall; and said stretchable wall includes a liner over said internal surface of the tubular supporting component, said stretchable wall further including a cover over said external surface of the tubular supporting component, said cover having a longitudinal length less than that of said tubular supporting component in order to thereby define an exposed end of the tubular supporting component.
Claim 3
Dependent Claim
24 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said porous elastomeric material is coated with a thin layer of silicone rubber.
Claim 4
Dependent Claim
50 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said liner covers substantially all of the internal surface of the tubular supporting component and said cover covers substantially all of said external surface of the tubular supporting component except at said exposed end of the tubular supporting component.
Claim 5
Dependent Claim
32 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said exposed longitudinal end of said tubular supporting component extends longitudinally beyond and is not completely covered by said stretchable wall.
Claim 6
Dependent Claim
34 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said cover has a longitudinal length less than that of said tubular supporting component whereby said exposed end is free of said cover.
Claim 7
Dependent Claim
30 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said liner is bonded to said cover at locations defined by said open areas of the tubular supporting component.
Claim 8
Dependent Claim
19 words
The expandable supportive endoluminal graft in accordance with claim 1, further including a window opening through said stretchable wall.
Claim 9
Dependent Claim
20 words
The expandable supportive endoluminal graft in accordance with claim 7, wherein said window opening is through said tubular supporting component.
Claim 10
Dependent Claim
30 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said land areas of the tubular supporting component comprise a plurality of braided wires with said open areas therebetween.
Claim 11
Dependent Claim
45 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said land areas of the tubular supporting component are generally sinusoidally configured wire that is helically wound into the tubular supporting component, said wire defining therebetween said open areas of the tubular supporting component.
Claim 12
Dependent Claim
41 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said land areas of the tubular supporting component are shaped as intersecting elongated lengths integral with each other and defining said openings therebetween to form a mesh-shaped tubular supporting component.
Claim 13
Dependent Claim
26 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein the endoluminal graft is subjected to surface treatment for enhanced bicompatibility or for drug therapy.
Claim 14
Dependent Claim
21 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said expandable supportive endoluminal graft is sized for endovascular use.
Claim 15
Dependent Claim
37 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said expandable supportive endoluminal graft is sized for use within body systems selected from the group consisting of venous circulation, tracheobronchial tree, gastrointestinal and genitourinary systems.
Claim 16
Dependent Claim
23 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said porous elastomeric material of the stretchable wall is an elastomeric polymer.
Claim 17
Dependent Claim
23 words
The expandable supportive endoluminal graft in accordance with claim 1, wherein said porous elastomeric material of the stretchable wall is a polycarbonate urethane.
Claim 18
Dependent Claim
28 words
The expandable supportive endoluminal graft in accordance with claim 1, further including a staple component that passes through one of said open areas of said tubular supporting component.
Claim 19
Dependent Claim
236 words
An expandable supportive endoluminal graft, comprising: a tubular supporting component with a longitudinal axis, an internal surface disposed toward the longitudinal axis, and an external surface spaced outwardly from and shaped complementarily with said internal surface, said tubular supporting component having a network of land areas with open areas defined therebetween, said tubular supporting component being expandable from a first diameter at which the expandable supportive endoluminal graft is insertable into a body pathway to a second diameter, said second diameter being greater than said first diameter; a stretchable wall of essentially inert biocompatible material, said stretchable wall being applied onto at least one of said internal surface and said external surface of the tubular supporting component, said stretchable wall having a first diameter size when said tubular supporting component is at its said first diameter and a larger second diameter size when said tubular supporting component is at its said second diameter; said stretchable wall is made from a porous elastomeric material that provides a structure which allows normal cellular invasion thereinto from the body pathway when implanted therewithin, said porous elastomeric material being selected from the group consisting of grafts constructed by electrostatic spinning of polymeric fibers, elution of particulate material from polymeric sheeting forming said wall, and solvent phase inversion from polymeric sheeting forming said wall; and a staple component that passes through one of said open areas of said tubular supporting component.
Claim 20
Dependent Claim
236 words
An expandable supportive endoluminal graft, comprising: a tubular supporting component with a longitudinal axis, an internal surface disposed toward the longitudinal axis, and an external surface spaced outwardly from and shaped complementarily with said internal surface, said tubular supporting component having a network of land areas with open areas defined therebetween, said tubular supporting component being expandable from a first diameter at which the expandable supportive endoluminal graft is insertable into a body pathway to a second diameter, said second diameter being greater than said first diameter; a stretchable wall of essentially inert biocompatible material, said stretchable wall being applied onto at least one of said internal surface and said external surface of the tubular supporting component, said stretchable wall having a first diameter size when said tubular supporting component is at its said first diameter and a larger second diameter size when said tubular supporting component is at its said second diameter; said stretchable wall is made from a porous elastomeric material that provides a structure which allows normal cellular invasion thereinto from the body pathway when implanted therewithin, said porous elastomeric material being selected from the group consisting of grafts constructed by electrostatic spinning of polymeric fibers, elution of particulate material from polymeric sheeting forming said wall, and solvent phase inversion from polymeric sheeting forming said wall; and a staple component that passes through one of said open areas of said tubular supporting component.
Claim 21
Independent Claim
145 words
A method for implanting a bifurcated expandable supportive endoluminal graft, comprising the steps of: providing an endoprosthesis which is a tubular supporting component with a stretchable wall applied to at least one generally cylindrical surface thereof, the tubular supporting component having a network of land areas with open areas defined therebetween, said tubular supporting component being expandable with said stretchable wall from a first diameter to a larger second diameter, said stretchable wall having an extension portion that extends beyond the tubular supporting component, the extension portion having at least two generally tubular branch sleeves; transluminally implanting the endoprosthesis into a body vessel having a branched passageway, said transluminally implanting step including positioning one of said branch sleeves into a branch of the branched passageway; and transluminally implanting a stent component into said branch sleeve while same is within the branch of the branched passageway.
Claim 22
Independent Claim
145 words
A method for implanting a bifurcated expandable supportive endoluminal graft, comprising the steps of: providing an endoprosthesis which is a tubular supporting component with a stretchable wall applied to at least one generally cylindrical surface thereof, the tubular supporting component having a network of land areas with open areas defined therebetween, said tubular supporting component being expandable with said stretchable wall from a first diameter to a larger second diameter, said stretchable wall having an extension portion that extends beyond the tubular supporting component, the extension portion having at least two generally tubular branch sleeves; transluminally implanting the endoprosthesis into a body vessel having a branched passageway, said transluminally implanting step including positioning one of said branch sleeves into a branch of the branched passageway; and transluminally implanting a stent component into said branch sleeve while same is within the branch of the branched passageway.
Claim 23
Dependent Claim
51 words
The method in accordance with claim 19, wherein the endoprosthesis transluminally implanting step includes positioning another of said branch sleeves into another branch of the branched passageway, and further including transluminally implanting another stent component into said another branch sleeve while same is within the another branch of the branched passageway.
Claim 24
Dependent Claim
278 words
An expandable supportive endoluminal graft, comprising: a tubular supporting component with a longitudinal axis, an internal surface disposed toward the longitudinal axis, and an external surface spaced outwardly from and shaped complementarily with said internal surface, said tubular supporting component having a network of land areas with open areas defined therebetween, said tubular supporting component being expandable from a first diameter at which the expandable supportive endoluminal graft is insertable into a body pathway to a second diameter, said second diameter being greater than said first diameter; a stretchable wall of essentially inert biocompatible material, said stretchable wall being applied onto at least one of said internal surface and said external surface of the tubular supporting component, said stretchable wall having a first diameter size when said tubular supporting component is at its said first diameter and a larger second diameter size when said tubular supporting component is at its said second diameter; said stretchable wall is made from a porous elastomeric material that provides a structure which allows normal cellular invasion thereinto from the body pathway when implanted therewithin, said porous elastomeric material being selected from the group consisting of grafts constructed by electrostatic spinning of polymeric fibers, elution of particulate material from polymeric sheeting forming said wall, and solvent phase inversion from polymeric sheeting forming said wall; and said stretchable wall includes a liner over said internal surface of the tubular supporting component, said stretchable wall further including a cover over said external surface of the tubular supporting component, said liner having a longitudinal length less than that of said tubular supporting component in order to thereby define an exposed end of the tubular supporting component.
Claim 25
Dependent Claim
278 words
An expandable supportive endoluminal graft, comprising: a tubular supporting component with a longitudinal axis, an internal surface disposed toward the longitudinal axis, and an external surface spaced outwardly from and shaped complementarily with said internal surface, said tubular supporting component having a network of land areas with open areas defined therebetween, said tubular supporting component being expandable from a first diameter at which the expandable supportive endoluminal graft is insertable into a body pathway to a second diameter, said second diameter being greater than said first diameter; a stretchable wall of essentially inert biocompatible material, said stretchable wall being applied onto at least one of said internal surface and said external surface of the tubular supporting component, said stretchable wall having a first diameter size when said tubular supporting component is at its said first diameter and a larger second diameter size when said tubular supporting component is at its said second diameter; said stretchable wall is made from a porous elastomeric material that provides a structure which allows normal cellular invasion thereinto from the body pathway when implanted therewithin, said porous elastomeric material being selected from the group consisting of grafts constructed by electrostatic spinning of polymeric fibers, elution of particulate material from polymeric sheeting forming said wall, and solvent phase inversion from polymeric sheeting forming said wall; and said stretchable wall includes a liner over said internal surface of the tubular supporting component, said stretchable wall further including a cover over said external surface of the tubular supporting component, said liner having a longitudinal length less than that of said tubular supporting component in order to thereby define an exposed end of the tubular supporting component.
Claim 26
Dependent Claim
23 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said porous elastomeric material of the stretchable wall is an elastomeric polymer.
Claim 27
Dependent Claim
23 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said porous elastomeric material of the stretchable wall is a polycarbonate urethane.
Claim 28
Dependent Claim
24 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said porous elastomeric material is coated with a thin layer of silicone rubber.
Claim 29
Dependent Claim
50 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said liner covers substantially all of the internal surface of the tubular supporting component except at said exposed end of the tubular supporting component, and said cover covers substantially all of said external surface of the tubular supporting component.
Claim 30
Dependent Claim
32 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said exposed longitudinal end of said tubular supporting component extends longitudinally beyond and is not completely covered by said stretchable wall.
Claim 31
Dependent Claim
30 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said liner is bonded to said cover at locations defined by said open areas of the tubular supporting component.
Claim 32
Dependent Claim
27 words
The expandable supportive endoluminal graft in accordance with claim 21, further including staple component that passes through one of said open areas of said tubular supporting component.
Claim 33
Dependent Claim
19 words
The expandable supportive endoluminal graft in accordance with claim 21, further including a window opening through said stretchable wall.
Claim 34
Dependent Claim
20 words
The expandable supportive endoluminal graft in accordance with claim 29, wherein said window opening is through said tubular supporting component.
Claim 35
Dependent Claim
30 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said land areas of the tubular supporting component comprise a plurality of braided wires with said open areas therebetween.
Claim 36
Dependent Claim
45 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said land areas of the tubular supporting component are generally sinusoidally configured wire that is helically wound into the tubular supporting component, said wire defining therebetween said open areas of the tubular supporting component.
Claim 37
Dependent Claim
41 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said land areas of the tubular supporting component are shaped as intersecting elongated lengths integral with each other and defining said openings therebetween to form a mesh-shaped tubular supporting component.
Claim 38
Dependent Claim
26 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein the endoluminal graft is subjected to surface treatment for enhanced bicompatibility or for drug therapy.
Claim 39
Dependent Claim
21 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said expandable supportive endoluminal graft is sized for endovascular use.
Claim 40
Dependent Claim
37 words
The expandable supportive endoluminal graft in accordance with claim 21, wherein said expandable supportive endoluminal graft is sized for use within body systems selected from the group consisting of venous circulation, tracheobronchial tree, gastrointestinal and genitourinary systems.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-09-06 | 2003-03-08 | 2003-09-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-09-06 | 2007-03-08 | 2007-09-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-09-06 | 2011-03-08 | 2011-09-07 | $7700.00 | Window Closed / Lapsed |