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US5717030A Expired / Lapsed US ⏱️ 0.0 years remaining

Adjunctive polymer system for use with medical device

Assignee: Tolmar Therapeutics Inc
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Filing: 1996-12-06
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Granted: 1998-02-10
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Expires: 2016-12-06
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Abstract

Abstract A medical device which is a surgically implantable device coated with an adjunctive polymer system. The adjunctive polymer system forms a solid matrix when introduced into a human or animal body. The adjunctive polymer system can contain a drug or a medicament which is released over time from the solid matrix. The adjunctive polymer system contacts body tissue into which the surgically implantable device is implanted.

Inventors

  • 👤 Richard L. Dunn
  • 👤 Gerald L. Yewey
  • 👤 Jeffrey L. Southard
  • 👤 John E. Urheim

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 20:03
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/44; A61L15/62; A61L15/64; A61L17/00; A61L17/06; A61L24/00; A61L24/001; A61L24/0042; A61L26/00; A61L26/0061; A61L26/0066; A61L26/0076; A61L26/009; A61L27/00; A61L27/50; A61L27/54; A61L27/58; A61L29/00; A61L29/14; A61L29/148; A61L29/16; A61L31/00; A61L31/14; A61L31/148; A61L31/16; A61L2300/00; A61L2300/40; A61L2300/43; A61L2300/60; A61L2300/602; A61L2300/606; A61L2300/62; Y; Y10; Y10S; Y10S528/00; Y10S528/905; Y10S602/00; Y10S602/904

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 139 words
A coated wound dressing for sealing a wound in an internal tissue or organ when placed in contact with the wound, comprising: a fibrous wound dressing coated with an adjunctive polymer system to form the coated wound dressing, wherein the adjunctive polymer system comprises a pharmaceutically acceptable, biodegradable thermoplastic polymer that is insoluble in water or body fluids mixed with a biocompatible organic solvent which solubilizes the polymer and is miscible to dispersible in water or body fluids and capable of dissipating or dispersing from the adjunctive polymer system into surrounding tissue fluid whereupon the organic solvent dissipates or disperses into the surrounding tissue and the thermoplastic polymer coagulates to form a solid matrix, the proportion of thermoplastic polymer and solvent, and the polymer molecular weight being selected so as to provide said dissipation or dispersion and said coagulation.
Claim 2
Dependent Claim 139 words
A coated wound dressing for sealing a wound in an internal tissue or organ when placed in contact with the wound, comprising: a fibrous wound dressing coated with an adjunctive polymer system to form the coated wound dressing, wherein the adjunctive polymer system comprises a pharmaceutically acceptable, biodegradable thermoplastic polymer that is insoluble in water or body fluids mixed with a biocompatible organic solvent which solubilizes the polymer and is miscible to dispersible in water or body fluids and capable of dissipating or dispersing from the adjunctive polymer system into surrounding tissue fluid whereupon the organic solvent dissipates or disperses into the surrounding tissue and the thermoplastic polymer coagulates to form a solid matrix, the proportion of thermoplastic polymer and solvent, and the polymer molecular weight being selected so as to provide said dissipation or dispersion and said coagulation.
Claim 3
Dependent Claim 27 words
The wound dressing according to claim 1, wherein the fibrous wound dressing is selected from the group consisting of fabric, mesh, webbing, cloth, net and combinations thereof.
Claim 4
Dependent Claim 19 words
The wound dressing according to claim 1, wherein a biologically active agent is incorporated into the adjunctive polymer system.
Claim 5
Dependent Claim 14 words
The wound dressing according to claim 1, wherein the fibrous wound dressing is biodegradable.
Claim 6
Dependent Claim 33 words
The wound dressing according to claim 3, wherein the biologically active agent is selected from the group consisting of antibiotics, analgesics, growth promoting agents, clotting agents, anesthetics, antiseptics, antioxidants, anti-inflammatories, and mixtures thereof.
Claim 7
Dependent Claim 36 words
The wound dressing according to claim 3, wherein the biologically active agent is contained within a controlled release component selected from the group consisting of a nanoparticle, cyclodextrin, microcapsule, micelle, liposome, fiber, bead, and combinations thereof.
Claim 8
Dependent Claim 36 words
The wound dressing according to claim 3, wherein the biologically active agent is a low water-solubility salt of the active agent, a complex of the active agent, a conjugate of the active agent, and combinations thereof.
Claim 9
Dependent Claim 26 words
The wound dressing according to claim 1, wherein the internal tissue or organ is selected from the group consisting of an artery, vein, liver and pancreas.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2001-02-09 2001-08-11 2002-02-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2005-02-09 2005-08-11 2006-02-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2009-02-09 2009-08-11 2010-02-10 $7700.00 Window Closed / Lapsed

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