US3991766A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Controlled release of medicaments using polymers from glycolic acid
Assignee: Wyeth Holdings LLC
•
Filing: 1975-04-03
•
Granted: 1976-11-16
•
Expires: 1995-04-03
Abstract
Abstract Polyhydroxyacetic ester, also called polyglycolic acid (PGA), has surgically useful mechanical properties. On implantation, in living mammalian tissue, the polyglycolic acid is absorbed, and replaced by living tissue. Sutures, clips and storage pellets having medicaments incorporated therein can be used for both their own mechanical properties and as a delayed release system for medicaments.
Inventors
- 👤 Edward Emil Schmitt
- 👤 Rocco Albert Polistina
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 18:35
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; A61F; A61F13/00; A61F13/00051; A61F13/00063; A61K9/70; A61L; A61L17/00; A61L17/005; A61L17/06; A61L17/10; A61L17/12; A61L27/00; A61L27/50; A61L27/54; A61F13/15; A61F13/551; A61F13/84; A61F13/8405; A61F2013/00089; A61F2013/00157; A61F2013/00217; A61F2013/00221; A61F2013/00361; A61F2013/00365; A61F2013/00519; A61F2013/00902; A61F2013/0091; A61F2013/15008; A61F2013/15048; A61L2300/00; A61L2300/40; A61L2300/402; A61L2300/404; A61L2300/406; A61L2300/60; A61L2300/602
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
25 words
A controlled release medicament device consisting of at least one filament of polyglycolic acid having incorporated therein a small but effective amount of an antibiotic.
Claim 2
Dependent Claim
25 words
A controlled release medicament device consisting of at least one filament of polyglycolic acid having incorporated therein a small but effective amount of an antibiotic.
Claim 3
Dependent Claim
31 words
A medicament repository consisting of a surgical element in the form of tubes, sheets, sponges, gauzes or prosthetic devices of polyglycolic acid having incorporated therein an effective amount of a medicament.
Claim 4
Dependent Claim
31 words
A medicament repository consisting of a surgical element in the form of tubes, sheets, sponges, gauzes or prosthetic devices of polyglycolic acid having incorporated therein an effective amount of a medicament.
Claim 5
Dependent Claim
24 words
The repository of claim 2 which is functionally effective as a tissue retaining clip or staple, as well as having a medicament release function.
Claim 6
Dependent Claim
114 words
In a surgical needle and suture combination the improvement comprising: a suture consisting of at least one filament of stretched and oriented normally solid polyglycolic acid, the said surgical needle and suture being sterile; the said suture having good knotability, good knot strength, good handleability, ready colorability, and a total denier of from 1 to 4,000, retaining a high proportion of its original strength for at least 3 days when embedded in living muscular tissue, being substantially absorbed in 90 days when embedded in living muscular tissue, and being substantially free from contaminants not absorbable by living muscular tissue, and having incorporated therein a small but effective quantity of an antibiotic, antiseptic, or anesthetic,
Claim 7
Dependent Claim
114 words
In a surgical needle and suture combination the improvement comprising: a suture consisting of at least one filament of stretched and oriented normally solid polyglycolic acid, the said surgical needle and suture being sterile; the said suture having good knotability, good knot strength, good handleability, ready colorability, and a total denier of from 1 to 4,000, retaining a high proportion of its original strength for at least 3 days when embedded in living muscular tissue, being substantially absorbed in 90 days when embedded in living muscular tissue, and being substantially free from contaminants not absorbable by living muscular tissue, and having incorporated therein a small but effective quantity of an antibiotic, antiseptic, or anesthetic,
Claim 8
Dependent Claim
10 words
The suture of claim 4 having incorporated therein an antibiotic.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-11-16 | 1980-05-17 | 1980-11-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-11-16 | 1984-05-17 | 1984-11-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-11-16 | 1988-05-17 | 1988-11-16 | $7700.00 | Window Closed / Lapsed |