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Connective tissue prosthesis

Assignee: United States Surgical Corp
•
Filing: 1990-09-12
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Granted: 1992-09-15
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Expires: 2010-09-12
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Abstract

Abstract A semi-bioabsorbable connective tissue prosthesis, e.g., a replacement for the human anterior cruciate ligament, is provided whose stress-strain characteristics closely match those of the natural tissue.

Inventors

  • 👤 Donald S. Kaplan
  • 👤 John Kennedy
  • 👤 Ross R. Muth

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:14
CPC Classifications
D; D02; D02G; D02G3/00; D02G3/44; D02G3/448; A; A61; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61L; A61L27/00; A61L27/50; A61L27/58; D02G3/22; D02G3/32; D02G3/328; D02G3/38; D04; D04C; D04C1/00; D04C1/06; D04C1/12; A61F2210/00; A61F2210/0004; A61L2430/00; A61L2430/10; D10; D10B; D10B2509/00

Claims Analysis

Total Claims: 62
Claim 1
Independent Claim 60 words
A connective tissue prosthesis comprising: a) a core made up of a first biocompatible composite yarn extending in a lengthwise direction; and b) a sheath surrounding the core, said sheath being fabricated from a second biocompatible yarn; the first composite yarn in said core (a) comprising a non-bioabsorbable core yarn component surrounded by an at least semi-bioabsorbable sheath yarn component.
Claim 2
Dependent Claim 60 words
A connective tissue prosthesis comprising: a) a core made up of a first biocompatible composite yarn extending in a lengthwise direction; and b) a sheath surrounding the core, said sheath being fabricated from a second biocompatible yarn; the first composite yarn in said core (a) comprising a non-bioabsorbable core yarn component surrounded by an at least semi-bioabsorbable sheath yarn component.
Claim 3
Dependent Claim 31 words
The connective tissue prosthesis of claim 1, wherein the second biocompatible yarn in said sheath (b) comprises a non-bioabsorbable core yarn component surrounded by an at least semi-bioabsorbable sheath yarn component.
Claim 4
Dependent Claim 14 words
The connective tissue prosthesis of claim 2 wherein the sheath yarn component is bioabsorbable.
Claim 5
Dependent Claim 23 words
The connective tissue prosthesis of claim 1 exhibiting stress-strain characteristics approximately those of the natural connective tissue replaced or augmented by the prosthesis.
Claim 6
Dependent Claim 18 words
The connective tissue prosthesis of claim 1 wherein said connective tissue prosthesis is a ligament or tendon prosthesis.
Claim 7
Dependent Claim 19 words
The connective tissue prosthesis of claim 1 wherein said connective tissue prosthesis is a human anterior cruciate ligament prosthesis.
Claim 8
Dependent Claim 17 words
The connective tissue prosthesis of claim 1 in which the core component comprises at least one filament.
Claim 9
Dependent Claim 19 words
The connective tissue prosthesis of claim 7 in which the core (a) of the prosthesis comprises multiple composite yarns.
Claim 10
Dependent Claim 14 words
The connective tissue prosthesis of claim 7 wherein the core component comprises multiple filaments.
Claim 11
Dependent Claim 17 words
The connective tissue prosthesis of claim 1 in which the sheath component comprises at least one filament.
Claim 12
Dependent Claim 15 words
The connective tissue prosthesis of claim 10 wherein the sheath yarn component comprises multiple filaments.
Claim 13
Dependent Claim 46 words
The connective tissue prosthesis of claim 1 in which the core component is manufactured from at least one polymeric material selected from the group consisting of polyethylene homopolymers, polypropylene homopolymers, ethylene-propylene copolymers, ethylene propylene terpolymers, fluorinated hydrocarbons, fluorosilicones, isobutylenes, isoprenes, polyacrylates, polybutadienes, polyurethanes, and polyether-polyester copolymers.
Claim 14
Dependent Claim 23 words
The connective tissue prosthesis of claim 1 in which the core component possesses an elongation at break of at least about 30 percent.
Claim 15
Dependent Claim 46 words
The connective tissue prosthesis of claim 1 in which the sheath component is an absorbable, relatively inelastic polymeric material derived at least in part from a monomer selected from the group consisting of glycolic acid, glycolide, lactic acid, lactide, p-dioxanone, trimethylene carbonate, e-caprolactone and hydroxycaproic acid.
Claim 16
Dependent Claim 16 words
The connective tissue prosthesis of claim 1 in which the sheath component is a lactide-glycolide copolymer.
Claim 17
Dependent Claim 27 words
The connective tissue prosthesis of claim 12 in which the sheath component is a lactide-glycolide copolymer containing from about 70 to about 90 mole percent lactide units.
Claim 18
Dependent Claim 27 words
The connective tissue prosthesis of claim 16 in which the sheath component is a lactide-glycolide copolymer containing from about 75 to about 85 mole percent lactide units.
Claim 19
Dependent Claim 20 words
The connective tissue prosthesis of claim 1 wherein the sheath (b) covering the core (a) is at least partially woven.
Claim 20
Dependent Claim 14 words
The connective tissue prosthesis of claim 18 wherein the sheath (b) is entirely woven.
Claim 21
Dependent Claim 14 words
The connective tissue prosthesis of claim 1 further comprising at least one bioactive substance.
Claim 22
Dependent Claim 18 words
The connective tissue prosthesis of claim 1, wherein said sheath component is helically wound about said core component.
Claim 23
Dependent Claim 23 words
The connective tissue prosthesis of claim 21, additionally comprising a second sheath component helically wound about said sheath component in a different direction.
Claim 24
Dependent Claim 17 words
The connective tissue prosthesis of claim 22, in which said second sheath component is a lactide-glycolide copolymer.
Claim 25
Dependent Claim 19 words
The connective tissue prosthesis of claim 22, wherein said first and second sheath components have different ratios of absorption.
Claim 26
Dependent Claim 17 words
The connective tissue prosthesis of claim 1, wherein said sheath component is braided around said core component.
Claim 27
Dependent Claim 26 words
The connective tissue prosthesis of claim 25, wherein said sheath component comprises a plurality of bioabsorbable fibers, said fibers comprising at least two different chemical compositions.
Claim 28
Dependent Claim 28 words
The connective tissue prosthesis of claim 1, wherein said core (a) and sheath (b) together are branched at discrete locations to form gaps between branches of said prosthesis.
Claim 29
Dependent Claim 31 words
The connective tissue prosthesis of claim 27, wherein a yarn is wrapped about said sheath (b) at discrete locations to at least temporarily retain said sheath (b) about said core (a).
Claim 30
Dependent Claim 27 words
The connective tissue prosthesis of claim 28, wherein said wrapping yarn comprises a biocompatible, non-bioabsorbable core yarn component surrounded by a at least semi-bioabsorbable sheath yarn component.
Claim 31
Dependent Claim 17 words
The connective tissue prosthesis of claim 29 wherein said sheath component of said wrapping yarn is bioabsorbable.
Claim 32
Dependent Claim 14 words
The connective tissue prosthesis of claim 1 wherein said sheath yarn component is bioabsorbable.
Claim 33
Dependent Claim 20 words
The connective tissue prosthesis of claim 1 wherein the sheath (b) covering the core (a) is at least partially braided.
Claim 34
Dependent Claim 14 words
The connective tissue prosthesis of claim 32 wherein the sheath (b) is entirely braided.
Claim 35
Dependent Claim 20 words
The connective tissue prosthesis of claim 1 wherein the sheath (b) covering the core (a) is at least partially knitted.
Claim 36
Dependent Claim 14 words
The connective tissue prosthesis of claim 34 wherein the sheath (b) is entirely knitted.
Claim 37
Dependent Claim 30 words
A connective tissue prosthesis comprising: a tubular component fabricated from composite yarn, said yarn comprising a biocompatible, core yarn component surrounded by a biocompatible, at least semi-bioabsorbable sheath yarn component.
Claim 38
Dependent Claim 30 words
A connective tissue prosthesis comprising: a tubular component fabricated from composite yarn, said yarn comprising a biocompatible, core yarn component surrounded by a biocompatible, at least semi-bioabsorbable sheath yarn component.
Claim 39
Dependent Claim 25 words
The connective tissue prosthesis of claim 36, comprising a center section where said yarn is unbraided and bordered by sections where said yarn is braided.
Claim 40
Dependent Claim 17 words
The connective tissue prosthesis of claim 37, additionally comprising a helical wrap about said unbraided center section.
Claim 41
Dependent Claim 33 words
The connective tissue prosthesis of claim 38, wherein said helical wrap is fabricated from composite yarn comprising a biocompatible, non-bioabsorbable core yarn component surrounded by a biocompatible, at least semi-absorbable sheath yarn component.
Claim 42
Dependent Claim 13 words
The connective tissue prosthesis of claim 39, wherein said sheath component is bioabsorbable.
Claim 43
Dependent Claim 42 words
The connective tissue prosthesis of claim 36, additionally comprising a threading member attached to an end thereof, said threading member comprising a composite yarn which comprises a biocompatible, non-bioabsorbable core yarn component surrounded by a biocompatible, at least semi-bioabsorbable sheath yarn component.
Claim 44
Dependent Claim 13 words
The connective tissue prosthesis of claim 41 wherein said sheath component is bioabsorbable.
Claim 45
Dependent Claim 13 words
The connective tissue prosthesis of claim 36 wherein said sheath component is bioabsorbable.
Claim 46
Dependent Claim 34 words
Method for manufacturing a connective tissue prosthesis, comprising forming said connective tissue prosthesis from a first biocompatible composite yarn comprising a non-bioabsorbable core yarn component surrounded by an at least semibioabsorbable sheath yarn component.
Claim 47
Dependent Claim 34 words
Method for manufacturing a connective tissue prosthesis, comprising forming said connective tissue prosthesis from a first biocompatible composite yarn comprising a non-bioabsorbable core yarn component surrounded by an at least semibioabsorbable sheath yarn component.
Claim 48
Dependent Claim 26 words
The method of claim 44, wherein said connective tissue prosthesis comprises a core and a sheath, said core being at least partially surrounded by said sheath.
Claim 49
Dependent Claim 13 words
The method of claim 45, wherein said biocompatible composite yarn forms said core.
Claim 50
Dependent Claim 13 words
The method of claim 44, wherein said biocompatible composite yarn forms said sheath.
Claim 51
Dependent Claim 13 words
The method of claim 44, wherein the sheath is woven about the core.
Claim 52
Dependent Claim 27 words
The method of claim 48, wherein the sheath is braided from braider bobbins loaded onto a carrier braider, and the core is pulled through the thus-braided sheath.
Claim 53
Dependent Claim 13 words
The method of claim 48 wherein the sheath is braided about the core.
Claim 54
Dependent Claim 11 words
The method of claim 44 wherein said sheath component is bioabsorbable.
Claim 55
Dependent Claim 13 words
The method of claim 44 wherein the sheath is knitted about the core.
Claim 56
Dependent Claim 33 words
Method for manufacturing a tubular connective tissue prosthesis, comprising forming a tubular component from composite yarn comprising a biocompatible, non-bioabsorbable core yarn component surrounded by a biocompatible, at least semi-absorbable sheath yarn component.
Claim 57
Dependent Claim 33 words
Method for manufacturing a tubular connective tissue prosthesis, comprising forming a tubular component from composite yarn comprising a biocompatible, non-bioabsorbable core yarn component surrounded by a biocompatible, at least semi-absorbable sheath yarn component.
Claim 58
Dependent Claim 13 words
The method of claim 53 wherein the tubular component is formed by weaving.
Claim 59
Dependent Claim 13 words
The method of claim 53 wherein the tubular component is formed by braiding.
Claim 60
Dependent Claim 19 words
The method of claim 55, wherein the tubular component is braided from braider bobbins loaded onto a carrier braider.
Claim 61
Dependent Claim 13 words
The method of claim 53 wherein the tubular component is formed by knitting.
Claim 62
Dependent Claim 11 words
The method of claim 53 wherein the sheath component is bioabsorbable.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-09-15 1996-03-16 1996-09-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-09-15 2000-03-16 2000-09-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-09-15 2004-03-16 2004-09-15 $7700.00 Window Closed / Lapsed

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