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US4996054A
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Antithrombogenic, non-calcifying material and method of making articles for medical purposes
Assignee: Beiersdorf AG
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Filing: 1988-10-19
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Granted: 1991-02-26
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Expires: 2008-10-19
Abstract
Abstract An antithrombogenic, non-calcifying, and elastic material on a basis of polyurethane, characterized by the addition of fatty-acid esters and optionally by the further addition of cross-linking agents that react with water.
Inventors
- 👤 Hanns Pietsch
- 👤 Holger Kartheus
- 👤 Hans-Joachim Holtzmann
- 👤 Gunther Sachau
- 👤 Helmut Reul
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:43
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/507; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2412; A61L27/02; A61L27/14; A61L27/18; A61L33/00; A61L33/0005; A61L33/06; A61L33/068; B; B29; B29C; B29C41/00; B29C41/02; B29C41/14; B29C41/20; B29C67/00; B29C67/24; B29C67/246; B29C70/00; B29C70/68; B29K; B29K2083/00; B29K2083/005; Y; Y10; Y10S; Y10S623/00; Y10S623/90
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
56 words
A method of forming a shaped article comprising shaping a composition comprising a polyurethane, a fatty acid ester and, as a cross-linking agent, an alkoxysilyl compound that contains at least two methoxysilyl, ethoxysilyl, propoxysilyl, or butoxysilyl groups and at least one amino group, and thereafter cross-linking the shaped mass through the action of water or humidity.
Claim 2
Independent Claim
56 words
A method of forming a shaped article comprising shaping a composition comprising a polyurethane, a fatty acid ester and, as a cross-linking agent, an alkoxysilyl compound that contains at least two methoxysilyl, ethoxysilyl, propoxysilyl, or butoxysilyl groups and at least one amino group, and thereafter cross-linking the shaped mass through the action of water or humidity.
Claim 3
Dependent Claim
22 words
A method according to claim 1, wherein the cross-linking agent is present in about 0.1 to 5% by weight of the polyurethane.
Claim 4
Dependent Claim
85 words
A method according to claim 1, wherein the fatty acid ester is an ester of an aliphatic, unbranched, saturated, or singly or doubly unsaturated monocarboxylic acid with 10 to 20 carbon atoms and a monovalent or polyvalent aliphatic alcohol with 1 to 6 carbon atoms or ascorbic acid, a polyoxyethylene fatty-acid ester, or a polyoxyethylene-sorbitane fatty-acid ester and is present in about 0.1 to 10% by weight of the polyurethane, and the polyurethane is a linear, segmented polyether-urethane urea or a linear, segmented polyester-urethane urea.
Claim 5
Dependent Claim
21 words
The method according to claim 3, wherein the ester is present in about 0.5 to 5% by weight of the polyurethane.
Claim 6
Dependent Claim
62 words
A shaped structure formed of a composition consisting essentially of a polyurethane, a fatty acid ester and an alkoxysilyl cross-linking agent which contains at least two methoxysilyl, ethoxysilyl, propoxysilyl or butoxysilyl groups and at least one amino group, the cross-linking agent being present in about 0.1 to 5% by weight of the polyurethane, the device produced therefrom being antithrombogenic, non-calcifying and elastic.
Claim 7
Dependent Claim
62 words
A shaped structure formed of a composition consisting essentially of a polyurethane, a fatty acid ester and an alkoxysilyl cross-linking agent which contains at least two methoxysilyl, ethoxysilyl, propoxysilyl or butoxysilyl groups and at least one amino group, the cross-linking agent being present in about 0.1 to 5% by weight of the polyurethane, the device produced therefrom being antithrombogenic, non-calcifying and elastic.
Claim 8
Dependent Claim
9 words
The device produced by the method of claim 1.
Claim 9
Dependent Claim
36 words
A shaped structure which in use comes into contact with blood, and which is formed by cross-linking a composition comprising a polyurethane, a fatty-acid ester and a cross-linking agent, the structure being antithromobogenic, non-calcifying and elastic.
Claim 10
Dependent Claim
36 words
A shaped structure which in use comes into contact with blood, and which is formed by cross-linking a composition comprising a polyurethane, a fatty-acid ester and a cross-linking agent, the structure being antithromobogenic, non-calcifying and elastic.
Claim 11
Dependent Claim
44 words
A shaped structure according to claim 7, wherein the structure is a cardiac valve, blood pump, a membrane, a coating on a cardiac-pacemaker electrode, an angiographic or cardiac cathether, an artificial pericardium, or a tube, valve or bag that comes into contact with blood.
Claim 12
Dependent Claim
33 words
A shaped structure which in use comes into contact with blood, and which is formed of a composition comprising a polyurethane and a fatty acid ester, the structure being antithromobogenic, non-calcifying and elastic.
Claim 13
Dependent Claim
33 words
A shaped structure which in use comes into contact with blood, and which is formed of a composition comprising a polyurethane and a fatty acid ester, the structure being antithromobogenic, non-calcifying and elastic.
Claim 14
Dependent Claim
41 words
An antithrombogenic, non-calcifying and elastic cardiac valve, blood pump, membrane, coating on a cardiac-pacemaker electrode, angiographic or cardiac catheter, artificial pericardium, or tube, valve or bag that comes into contact with blood, produced by cross-linking a composition according to claim 9.
Claim 15
Dependent Claim
34 words
A shaped structure according to claim 9, wherein the structure is a membrane, an angiographic or cardiac catheter, or a tube, valve, bag or blood pump that in use comes into contact with blood.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-02-25 | 1994-08-27 | 1995-02-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-02-25 | 1998-08-27 | 1999-02-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-02-25 | 2002-08-27 | 2003-02-26 | $7700.00 | Window Closed / Lapsed |