Patent US4952419A successfully refreshed from Google Patents.
US4952419A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of making antimicrobial coated implants
Assignee: Eli Lilly and Co
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Filing: 1989-03-12
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Granted: 1990-08-28
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Expires: 2009-03-12
Abstract
Abstract Uniform adherent coatings of antimicrobial agents are applied to the surface of implants by applying a film of silicone oil to the surface of the implant and then contacting the film-bearing surface with antimicrobial agents in a film-adherent powder form. A durable antimicrobial coating is formed. The coated implants can be packaged using mechanized implant handling equipment without significant loss of the antimicrobial coating.
Inventors
- 👤 Jose De Leon
- 👤 Thomas H. Ferguson
- 👤 Daniel S. Skinner, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:00
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/28; A61K9/0012; A61K9/0019; A61K9/0024; A61K9/2072; A61K9/2086; A61K9/209; A61L; A61L27/00; A61L27/50; A61L27/54; A61L2300/00; A61L2300/20; A61L2300/22; A61L2300/222; A61L2300/40; A61L2300/404; A61L2300/406; A61L2300/45; A61L2300/60; A61L2300/606; Y; Y10; Y10S; Y10S128/00; Y10S128/21; Y10S623/00; Y10S623/901
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
49 words
A method for forming an adherent antimicrobial coating on a surface of an implant comprising the steps of applying a silicone fluid to form a film of silicone fluid on the surface of the implant and contacting the film-bearing surface with an antimicrobial agent in a film-adherent powder form.
Claim 2
Independent Claim
49 words
A method for forming an adherent antimicrobial coating on a surface of an implant comprising the steps of applying a silicone fluid to form a film of silicone fluid on the surface of the implant and contacting the film-bearing surface with an antimicrobial agent in a film-adherent powder form.
Claim 3
Dependent Claim
22 words
The method of claim 1 wherein the implant is a drug delivery device comprising a silicone polymer matrix and an anabolic agent.
Claim 4
Dependent Claim
19 words
The method of claim 1 wherein the silicone fluid has a viscosity of about 200 to about 500 centistokes.
Claim 5
Dependent Claim
25 words
The method of claim 3 wherein the silicone fluid is applied to the surface of the implant by spraying the fluid onto the implant surface.
Claim 6
Dependent Claim
33 words
The method of claim 3 wherein the silicone fluid is applied to the surface of the implant by contacting said implant surface with a second surface bearing a film of said silicone fluid.
Claim 7
Dependent Claim
18 words
The method of claim 2 wherein the silicone polymer matrix forms a coating around an inert polymeric core.
Claim 8
Dependent Claim
34 words
The method of claim 6 wherein the silicone fluid has a viscosity of about 200 to about 500 centistokes and the film bearing implant surface is contacted with oxytetracycline in a film-adherent powder form.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-08-27 | 1994-02-26 | 1994-08-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-08-27 | 1998-02-26 | 1998-08-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-08-27 | 2002-02-26 | 2002-08-28 | $7700.00 | Window Closed / Lapsed |