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US4941870A
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Method for manufacturing a synthetic vascular prosthesis
Assignee: JMS Co Ltd
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Filing: 1988-12-30
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Granted: 1990-07-17
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Expires: 2008-12-30
Abstract
Abstract A synthetic vascular prosthesis comprises a hollow tubular base member having a multitude of continuous pores and formed of an elastomer material, and a hydrogel layer formed on the inner surface of the base member. The hydrogel layer is partly embedded in the inner portion of the base member at the pores, thereby permitting anchoring adhesion between the hydrogel layer and the base member. A method for manufacturing the synthetic vascular prosthesis is also disclosed, in which the formation of pores in the base member is effected by two separate steps and the hydrogel layer is formed after formation of an inner porous portion of the base member.
Inventors
- 👤 Masao Okada
- 👤 Kazuhiko Sakai
- 👤 Haruo Kimura
- 👤 Yoshito Ikada
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 10:45
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/56; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61L27/14; A61L27/16; A61L27/28; A61L27/34; A61L27/507; A61L27/52; Y; Y10; Y10S; Y10S623/00; Y10S623/901
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
158 words
A method for manufacturing a synthetic vascular prosthesis comprising the steps of: dissolving an elastomer material in a solvent; adding an inorganic salt to the solution and adjusting the viscosity of the solution; subjecting the solution to extrusion into a hollow tube; cutting said tube to a predetermined length to form a tubular base member; removing the solvent from said base member and drying said base member; removing the inorganic salt in the inner portion of said base member by dissolution with an acid to form a porous inner portion of said base member; coating a hydrogel material inside of said base member so that said hydrogel material, forms a hydrogel layer on said base member with partial infiltrating into the pores of said porous inner portion; and further removing the inorganic salt in the outer portion of said base member by dissolution with an acid, thereby forming a porous outer portion having a multitude of continuous pores.
Claim 2
Independent Claim
158 words
A method for manufacturing a synthetic vascular prosthesis comprising the steps of: dissolving an elastomer material in a solvent; adding an inorganic salt to the solution and adjusting the viscosity of the solution; subjecting the solution to extrusion into a hollow tube; cutting said tube to a predetermined length to form a tubular base member; removing the solvent from said base member and drying said base member; removing the inorganic salt in the inner portion of said base member by dissolution with an acid to form a porous inner portion of said base member; coating a hydrogel material inside of said base member so that said hydrogel material, forms a hydrogel layer on said base member with partial infiltrating into the pores of said porous inner portion; and further removing the inorganic salt in the outer portion of said base member by dissolution with an acid, thereby forming a porous outer portion having a multitude of continuous pores.
Claim 3
Dependent Claim
22 words
A method according to claim 1, wherein said elastomer material is selected from the group consisting polyether-segmented polyurethanes and polyether-segmented polyurethane ureas.
Claim 4
Dependent Claim
19 words
A method according to claim 2, wherein said solvent is selected from the group consisting or tetrahydrofuran and dimethylformamide.
Claim 5
Dependent Claim
25 words
A method according to claim 1, wherein said inorganic salt is selected from the group of particles of calcium carbonate, magnesium oxide and magnesium hydroxide.
Claim 6
Dependent Claim
28 words
A method according to claim 1, wherein more than 500 parts by weight of said inorganic salt is added per 100 parts by weight of said elastomer material.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-07-16 | 1994-01-15 | 1994-07-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-07-16 | 1998-01-15 | 1998-07-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-07-16 | 2002-01-15 | 2002-07-17 | $7700.00 | Window Closed / Lapsed |