US4851586A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1,4-naphthalenediol and 1,4-hydroquinone derivatives
Assignee: Pharmacia and Upjohn Co
•
Filing: 1986-09-05
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Granted: 1989-07-25
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Expires: 2006-09-05
Abstract
Abstract Novel 1,4-naphthalenediol and 1,4-hydroquinone derivatives of formulas I, II, III and IV and their therapeutic uses as 5-lipoxygenase inhibitors, leukotriene inhibitors, antiinflammatory and/or inhibitors of mucus secretion agents are described. Also provided are novel intermediates useful for the preparation of said derivatives. ##STR1##
Inventors
- 👤 Gordon L. Bundy
- 👤 Chiu-Hong Lin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:25
CPC Classifications
C; C07; C07C; C07C50/00; C07C50/26; C07C50/32; C07C43/00; C07C43/02; C07C43/20; C07C43/215; C07C43/23; C07C46/00; C07C46/02; C07C46/06; C07C50/02; C07C50/06; C07C50/10; C07C50/14; C07C50/24; C07C50/28; C07C50/38; C07D; C07D309/00; C07D309/02; C07D309/08; C07D309/10; C07D309/12
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
42 words
A compound having the formula wherein R 1 is hydrogen; R 2 is --C.tbd.C--(CH 2 ) m --C.tbd.C--(CH 2 ) p --OR 1 and n is 3 or 4, m is 1 to 5, inclusive and p is 0 to 3 inclusive.
Claim 2
Dependent Claim
42 words
A compound having the formula wherein R 1 is hydrogen; R 2 is --C.tbd.C--(CH 2 ) m --C.tbd.C--(CH 2 ) p --OR 1 and n is 3 or 4, m is 1 to 5, inclusive and p is 0 to 3 inclusive.
Claim 3
Dependent Claim
6 words
A compound of claim 1, 2-(11-hydroxyundeca-4,9-diynyl)-1-hydroxy-4-methoxynaphthalene.
Claim 4
Dependent Claim
6 words
A compound of claim 1, 2-(12-hydroxydodeca-5,10-diynyl)-1-hydroxy-4-methoxynaphthalene.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-07-24 | 1993-01-23 | 1993-07-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-07-24 | 1997-01-23 | 1997-07-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-07-24 | 2001-01-23 | 2001-07-25 | $7700.00 | Window Closed / Lapsed |