Patent US4822361A successfully refreshed from Google Patents.
US4822361A
Expired / Lapsed
US
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Tubular prosthesis having a composite structure
Assignee: Sumitomo Electric Industries Ltd
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Filing: 1986-12-24
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Granted: 1989-04-18
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Expires: 2006-12-24
Abstract
Abstract A tubular prosthesis having a composite structure comprising (i) tubular polytetrafluoroethylene having a microfibrous structure comprising small nodes interconnected with fibrils and (ii) materials which can be absorbed by a living body wherein (a) said polytetrafluoroethylene has a greater average fibril length on the outer surface than on the inner surface, and the fibrous structure of said polytetrafluoroethylene varies continuously across the thickness of the tube wall wherein said inner surface has said fibrous structure being predominantly oriented along the axial direction and said outer surface has said fibrous structure being predominantly oriented along the concentric direction; and (b) said materials which can be absorbed by a living body are collagen, at least one of albumin and chitosan, and heparin, and are distributed in such a manner that collagen is present in the portion of the tube wall which is closest to the outer surface thereof while at least one of albumin and chitosan is present in the portion of the tube wall which is closest to the inner surface thereof, and heparin is present in the inner surface of the tube wall.
Inventors
- 👤 Koichi Okita
- 👤 Shigeru Asako
- 👤 Katsuya Yamada
- 👤 Kazuhiro Okabe
- 👤 Tohru Kashiwagi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:58
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/28; A61L27/34; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61L27/14; A61L27/16
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
202 words
A tubular prosthesis having a composite structure comprising (i) tubular polytetrafluoroethylene having a microfibrous structure comprising small nodes interconnected with fibrils and (ii) materials which can be absorbed by a living body wherein (a) said polytetrafluoroethylene has a greater average fibril length on the outer surface than on the inner surface, and the fibrous structure of said polytetrafluoroethylene varies continuously across the thickness of the tube wall wherein said inner surface has said fibrous structure being predominantly oriented along the axial direction and said outer surface has said fibrous structure being predominantly oriented along the concentric direction; and (b) said materials which can be absorbed by a living body are collagen, at least one of albumin and chitosan, and heparin, and are distributed in such a manner that collagen is present only in the portion of the tube wall which is closest to the outer surface thereof or the outer surface of the tube wall while at least one of albumin and chitosan is present only in the portion of the tube wall which is closest to the inner surface thereof or the inner surface of the tube wall, and heparin is present only in the inner surface of the tube wall.
Claim 2
Dependent Claim
202 words
A tubular prosthesis having a composite structure comprising (i) tubular polytetrafluoroethylene having a microfibrous structure comprising small nodes interconnected with fibrils and (ii) materials which can be absorbed by a living body wherein (a) said polytetrafluoroethylene has a greater average fibril length on the outer surface than on the inner surface, and the fibrous structure of said polytetrafluoroethylene varies continuously across the thickness of the tube wall wherein said inner surface has said fibrous structure being predominantly oriented along the axial direction and said outer surface has said fibrous structure being predominantly oriented along the concentric direction; and (b) said materials which can be absorbed by a living body are collagen, at least one of albumin and chitosan, and heparin, and are distributed in such a manner that collagen is present only in the portion of the tube wall which is closest to the outer surface thereof or the outer surface of the tube wall while at least one of albumin and chitosan is present only in the portion of the tube wall which is closest to the inner surface thereof or the inner surface of the tube wall, and heparin is present only in the inner surface of the tube wall.
Claim 3
Dependent Claim
35 words
A tubular prosthesis having a composite structure as in claim 1, wherein the outer surface of said tubular polytetrafluoroethylene has an average fibril length which is at least 5 times that of the inner surface.
Claim 4
Dependent Claim
35 words
A tubular prosthesis having a composite structure as in claim 2, wherein the outer surface of said tubular polytetrafluoroethylene has an average fibril length which is at least 10 times that of the inner surface.
Claim 5
Dependent Claim
38 words
A tubular prosthesis having a composite structure as in claim 1, wherein the nodes in the outer surface of said tubular polytetrafluoroethylene have a thickness which is at least 10 times that of nodes in the inner surface.
Claim 6
Dependent Claim
35 words
A tubular prosthesis having a composite structure as in claim 1, wherein said collagen has been freed of any antigenic groups by the treatment with pepsin and has been crosslinked with glutaraldehyde or dialdehyle starch.
Claim 7
Dependent Claim
22 words
A tubular prosthesis having a composite structure as in claim 1, wherein said chitosan has been crosslinked with glutaraldehyde or dialdehyde starch.
Claim 8
Dependent Claim
24 words
A tubular prosthesis having a composite structure as in claim 1, wherein said tubular prosthesis has an inner diameter of 5 mm or less.
Claim 9
Dependent Claim
25 words
A tubular prosthesis having a composite structure as in claim 7, wherein said tubular prosthesis has an inner diameter of from 1 to 3 mm.
Claim 10
Dependent Claim
23 words
A tubular prosthesis having a composite structure as in claim 1, wherein said tubular polytetrafluoroethylene has a porosity of from 70 to 90%.
Claim 11
Dependent Claim
23 words
A tubular prosthesis having a composite structure as in claim 9, wherein said tubular polytetrafluoroethylene has a porosity of from 75 to 80%.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-04-17 | 1992-10-17 | 1993-04-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-04-17 | 1996-10-17 | 1997-04-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-04-17 | 2000-10-17 | 2001-04-18 | $7700.00 | Window Closed / Lapsed |