Patent US4678757A successfully refreshed from Google Patents.
US4678757A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device and method for whole blood separation and analysis
Assignee: SmithKline Diagnostics Inc
•
Filing: 1985-04-11
•
Granted: 1987-07-07
•
Expires: 2005-04-11
Abstract
Abstract A method and device for separating blood into fluid and cellular fractions for diagnostic tests. The whole blood is introduced to a carrier containing a layer of carbohydrate which results in the rapid separation of the fluid from the cellular fractions. In a preferred embodiment, the device is fabricated in a sandwich design containing layers of carbohydrate and reagent material between two layers of plastic.
Inventors
- 👤 Myron C. Rapkin
- 👤 Ronald J. Schoengold
- 👤 David R. Shockey
- 👤 Pierre C. Van Rysselberghe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:35
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/521; G01N33/523; Y; Y10; Y10S; Y10S435/00; Y10S435/805; Y10T; Y10T436/00; Y10T436/25; Y10T436/25375; Y10T436/255
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
95 words
A test device for separating the fluid portion from whole blood and detecting soluble components in whole blood which comprises a first impermeable carrier having applied thereon a sugar and a second impermeable carrier having incorporated thereon a test reagent specifically reactable with a component to be detected, said first and second carriers being affixed to one another substantially along their entire juxtaposed peripheral edges defining an opening there-between and so layered that the sugar and reagent are in contiguous facing relationship, wherein said opening and carriers permit capillary and longitudinal transport of the blood.
Claim 2
Dependent Claim
95 words
A test device for separating the fluid portion from whole blood and detecting soluble components in whole blood which comprises a first impermeable carrier having applied thereon a sugar and a second impermeable carrier having incorporated thereon a test reagent specifically reactable with a component to be detected, said first and second carriers being affixed to one another substantially along their entire juxtaposed peripheral edges defining an opening there-between and so layered that the sugar and reagent are in contiguous facing relationship, wherein said opening and carriers permit capillary and longitudinal transport of the blood.
Claim 3
Dependent Claim
19 words
The device of claim 1 wherein the first carrier is a polyester and the second carrier is a polycarbonate.
Claim 4
Dependent Claim
17 words
The device of claim 1 wherein the first carrier is opaque and the second carrier is transparent.
Claim 5
Dependent Claim
10 words
The device of claim 1 wherein the sugar is mannitol.
Claim 6
Dependent Claim
48 words
A method for separating whole blood into fluid and cellular fractions which comprises applying the blood to the device of claim 1 whereby the cellular fraction remains in close proximity to the site of contact and the fluid fraction migrates in a longitudinal fashion away from said site.
Claim 7
Dependent Claim
10 words
The method of claim 5 wherein the sugar is mannitol.
References Cited (Backward Citations)
US3146163A
Cited
US3552925A
Cited
US3552928A
Cited
US4256693A
Cited
US4248829A
Cited
US4288228A
Cited
US4477575A
Cited
US4477575B1
Cited
US4330299A
Cited
US4524133A
Cited
US4476222A
Cited
US4543338A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-07-06 | 1991-01-05 | 1991-07-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-07-06 | 1995-01-05 | 1995-07-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-07-06 | 1999-01-05 | 1999-07-07 | $7700.00 | Window Closed / Lapsed |