US4476222A
Expired / Lapsed
US
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Test piece for quantitative analysis of substances in body fluids
Assignee: Eiken Chemical Co Ltd
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Filing: 1982-09-27
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Granted: 1984-10-09
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Expires: 2002-09-27
Abstract
Abstract A testing piece for quantitative analysis of a substance in a body fluid, particularly in blood, said testing piece comprising an absorbent carrier containing in it reagents for measuring the substance and coated with a mixture of polymethylmethacrylate and polyvinyl formal. This testing piece enables the efficient and swift quantitative analysis of the substance in body fluid, especially in blood, in a short time without preliminary separating the serum from the blood.
Inventors
- 👤 Mikio Ohtani
- 👤 Hiroshi Wada
- 👤 Yuzo Kosaka
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 03:41
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/525; C; C12; C12Q; C12Q1/00; C12Q1/26; C12Q1/32; C12Q1/54; Y; Y10; Y10S; Y10S435/00; Y10S435/805
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
49 words
A test piece for quantitative analysis of a substance in body fluid, said test piece comprising: an absorbent carrier, reagents for measuring the substance, said reagents being contained in said absorbent carrier, and a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal.
Claim 2
Dependent Claim
49 words
A test piece for quantitative analysis of a substance in body fluid, said test piece comprising: an absorbent carrier, reagents for measuring the substance, said reagents being contained in said absorbent carrier, and a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal.
Claim 3
Dependent Claim
33 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 1, wherein the weight ratio of polymethylmethacrylate to polyvinyl formal in the coating is between 9:1 and 1:9.
Claim 4
Dependent Claim
23 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 2, wherein said weight ratio is around 1:1.
Claim 5
Dependent Claim
42 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 1 wherein the absorbent carrier is a member selected from the group consisting of filter paper, cotton, wood piece, synthetic fiber paper, glass fiber, and porous plastics.
Claim 6
Dependent Claim
23 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 4, wherein the absorbent carrier is filter paper.
Claim 7
Dependent Claim
29 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 1 wherein a surface of said test piece is carried by a plastic sheet.
Claim 8
Dependent Claim
32 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 1 wherein said reagent comprises glucose oxidase, a substance having a peroxidase activity, and an oxidizable indicator.
Claim 9
Dependent Claim
32 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 4, wherein said reagent comprises glucose oxidase, a substance having a peroxidase activity, and an oxidizable indicator.
Claim 10
Dependent Claim
32 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 6, wherein said reagent comprises glucose oxidase, a substance having a peroxidase activity, and an oxidizable indicator.
Claim 11
Dependent Claim
32 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 1 wherein said reagent comprises galactose oxidase, a substance having a peroxidase activity, and an oxidizable indicator.
Claim 12
Dependent Claim
32 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 4, wherein said reagent comprises galactose oxidase, a substance having a peroxidase activity, and an oxidizable indicator.
Claim 13
Dependent Claim
32 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 6, wherein said reagent comprises galactose oxidase, a substance having a peroxidase activity, and an oxidizable indicator.
Claim 14
Dependent Claim
30 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 1 wherein said reagent comprises alcohol dehydrogenase, nicotine ademine dinucleotide diaphorase and a tetrazolium salt.
Claim 15
Dependent Claim
30 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 4, wherein said reagent comprises alcohol dehydrogenase, nicotine ademine dinucleotide, diaphorase, and a tetrazolium salt.
Claim 16
Dependent Claim
30 words
A test piece for quantitative analysis of a substance in body fluid claimed in claim 6, wherein said reagent comprises alcohol dehydrogenase, nicotine ademine dinucleotide, diaphorase and a tetrazolium salt.
Claim 17
Dependent Claim
72 words
A test piece for quantitative analysis of a substance in body fluid, comprising: A. an absorbent carrier; and B. a reagent in said absorbent carrier, said reagent being glucose oxidase, a substance having a peroxidase activity, and an oxidizable indicator; and C. a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal, wherein the weight ratio of polymethylmethacrylate to polyvinyl formal is between 9:1 and 1:9.
Claim 18
Dependent Claim
72 words
A test piece for quantitative analysis of a substance in body fluid, comprising: A. an absorbent carrier; and B. a reagent in said absorbent carrier, said reagent being glucose oxidase, a substance having a peroxidase activity, and an oxidizable indicator; and C. a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal, wherein the weight ratio of polymethylmethacrylate to polyvinyl formal is between 9:1 and 1:9.
Claim 19
Dependent Claim
72 words
A test piece for quantitative analysis of a substance in body fluid, comprising: A. an absorbent carrier; and B. a reagent in said absorbent carrier, said reagent being galactose oxidase, a substance having a peroxidase activity, and an oxidizable indicator; and C. a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal, wherein the weight ratio of polymethylmethacrylate to polyvinyl formal is between 9:1 and 1:9.
Claim 20
Dependent Claim
72 words
A test piece for quantitative analysis of a substance in body fluid, comprising: A. an absorbent carrier; and B. a reagent in said absorbent carrier, said reagent being galactose oxidase, a substance having a peroxidase activity, and an oxidizable indicator; and C. a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal, wherein the weight ratio of polymethylmethacrylate to polyvinyl formal is between 9:1 and 1:9.
Claim 21
Dependent Claim
70 words
A test piece for quantitative analysis of a substance in body fluid, comprising: A. an absorbent carrier; and B. a reagent in said absorbent carrier, said reagent being alcohol dehydrogenase, nicotine ademine dinucleotide diaphorase and a tetrazolium salt; and C. a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal, wherein the weight ratio of polymethylmethacrylate to polyvinyl formal is between 9:1 to 1:9.
Claim 22
Dependent Claim
70 words
A test piece for quantitative analysis of a substance in body fluid, comprising: A. an absorbent carrier; and B. a reagent in said absorbent carrier, said reagent being alcohol dehydrogenase, nicotine ademine dinucleotide diaphorase and a tetrazolium salt; and C. a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal, wherein the weight ratio of polymethylmethacrylate to polyvinyl formal is between 9:1 to 1:9.
Claim 23
Dependent Claim
73 words
A test piece for quantitative analysis of glucose in body fluid comprising: A. an absorbent carrier, said absorbent carrier being filter paper; and B. a reagent in said absorbent carrier, said reagent comprising glucose oxidase, a substance having a peroxidase activity, and an oxidizable indicator; and C. a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal, the weight ratio of polymethylmethacrylate to polyvinyl formal being 1:1.
Claim 24
Dependent Claim
73 words
A test piece for quantitative analysis of glucose in body fluid comprising: A. an absorbent carrier, said absorbent carrier being filter paper; and B. a reagent in said absorbent carrier, said reagent comprising glucose oxidase, a substance having a peroxidase activity, and an oxidizable indicator; and C. a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal, the weight ratio of polymethylmethacrylate to polyvinyl formal being 1:1.
Claim 25
Dependent Claim
120 words
A test piece for quantitative analysis of a substance in body fluid, said test piece comprising: A. an absorbent carrier, wherein said absorbent carrier is a member selected from the group consisting of filter paper, cotton, wood piece, synthetic fiber paper, glass fiber, and porous plastics; and B. a reagent in said absorbent carrier, said reagent comprising: 1. a substance having a peroxidase activity, 2. an oxidizable indicator, and 3. a member selected from the group consisting of glucose oxidase, pyruvic acid oxidase, galactose oxidase, and alcohol dehydrogenase; and C. a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal, wherein the weight ratio of polymethylmethacrylate to polyvinyl formal is between 9:1 and 1:9.
Claim 26
Dependent Claim
120 words
A test piece for quantitative analysis of a substance in body fluid, said test piece comprising: A. an absorbent carrier, wherein said absorbent carrier is a member selected from the group consisting of filter paper, cotton, wood piece, synthetic fiber paper, glass fiber, and porous plastics; and B. a reagent in said absorbent carrier, said reagent comprising: 1. a substance having a peroxidase activity, 2. an oxidizable indicator, and 3. a member selected from the group consisting of glucose oxidase, pyruvic acid oxidase, galactose oxidase, and alcohol dehydrogenase; and C. a coating on a surface of the absorbent carrier, said coating comprising polymethylmethacrylate and polyvinyl formal, wherein the weight ratio of polymethylmethacrylate to polyvinyl formal is between 9:1 and 1:9.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-10-09 | 1988-04-09 | 1988-10-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-10-09 | 1992-04-09 | 1992-10-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-10-09 | 1996-04-09 | 1996-10-09 | $7700.00 | Window Closed / Lapsed |