US4673584A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for providing articles with a biocompatible surface layer
Assignee: Astra Tech AB
•
Filing: 1986-03-05
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Granted: 1987-06-16
•
Expires: 2006-03-05
Abstract
Abstract A process for providing a surface of glass, silicon, aluminum or silicone rubber of an article useful within medicine with a bicompatible surface layer. Said surface is reacted (after oxidation when required) with a silane containing at least one epoxy group and the surface thus treated is then reacted with a polysaccharide containing at least one hydroxyl group. The invention also relates to an article exhibiting a biocompatible surface layer of a polysaccharide containing at least one hydroxyl group, which polysaccharide is covalently bound to a surface of glass, silicon, aluminum or silicone rubber of the article by means of a silane.
Inventors
- 👤 Bo H. Nygren
- 👤 Johan E. Stenberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:30
CPC Classifications
A; A61; A61L; A61L33/00; A61L33/0005; A61L33/0011; A61L33/0029; A61L33/06; A61L33/08; C; C08; C08K; C08K3/00; C08K3/02; C08K3/08; C08K3/40; C08K5/00; C08K5/54; C08L; C08L83/00; C08L83/04; Y; Y10; Y10T; Y10T428/00; Y10T428/13; Y10T428/131; Y10T428/1317; Y10T428/1321; Y10T428/1352; Y10T428/1355; Y10T428/1386; Y10T428/139; Y10T428/1393; Y10T428/31504; Y10T428/31511; Y10T428/31515; Y10T428/31518; Y10T428/31522; Y10T428/31551; Y10T428/31609; Y10T428/31612; Y10T428/31652; Y10T428/31663; Y10T428/31971
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
65 words
A process for providing articles exhibiting at least one surface of glass, silicon, aluminum or silicone rubber with a biocompatible surface layer, wherein said surface of the article, after oxidation thereof when said article is silicone rubber, is reacted with a silane containing at least one epoxy group and wherein the surface thus treated is reacted with a polysaccharide containing at least one hydroxyl group.
Claim 2
Dependent Claim
65 words
A process for providing articles exhibiting at least one surface of glass, silicon, aluminum or silicone rubber with a biocompatible surface layer, wherein said surface of the article, after oxidation thereof when said article is silicone rubber, is reacted with a silane containing at least one epoxy group and wherein the surface thus treated is reacted with a polysaccharide containing at least one hydroxyl group.
Claim 3
Dependent Claim
15 words
A process according to claim 1, wherein a neutral polysaccharide is used as said saccharide.
Claim 4
Dependent Claim
14 words
A process according to claim 2, wherein dextran is used as said neutral polysaccharide.
Claim 5
Dependent Claim
47 words
A process according to claim 1 wherein the silane is an alkoxysilane of the formula R-Si(alkoxy) 3 , or a chlorosilane, of the formula R-SiCl 3 and wherein R represents an epoxy group ##STR5## which is coupled to the silicone atom by means of a hydrocarbon chain.
Claim 6
Dependent Claim
13 words
A process according to claim 1 wherein the silane is 3-glycidoxypropyl trimethoxy silane.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-06-15 | 1990-12-15 | 1991-06-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-06-15 | 1994-12-15 | 1995-06-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-06-15 | 1998-12-15 | 1999-06-16 | $7700.00 | Window Closed / Lapsed |