Patent US4487865A successfully refreshed from Google Patents.
US4487865A
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Polymeric articles modified with hyaluronate
Assignee: Sanofi Biosurgery Inc
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Filing: 1983-12-15
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Granted: 1984-12-11
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Expires: 2003-12-15
Abstract
Abstract Polymeric materials (and articles made therefrom) including polyurethanes, polyesters, polyolefins, polyamides, polysiloxanes, vinylic and acrylic polymers are rendered biocompatible by including with the polymeric material hyaluronic acid or a salt thereof. The hyaluronic acid may be coated onto the surface of the polymeric material, dispersed throughout the body of the polymeric material, or both. The hyaluronic acid on the surface of the polymeric material may optionally be cross-linked. The biocompatible polymeric materials are used in the making of various prosthetic devices including heart valves, intraocular lenses, vascular grafts, pacemaker leads and the like.
Inventors
- 👤 Endre A. Balazs
- 👤 David J. Wedlock
- 👤 Glyn O. Phillips
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 06:37
CPC Classifications
C; C08; C08F; C08F8/00; A; A61; A61L; A61L27/00; A61L27/14; A61L27/16; A61L27/18; A61L27/50; A61L27/54; C08L; C08L75/00; C08L75/04; A61F; A61F2/00; A61F2/02; A61F2/14; A61F2/16; A61L2300/00; A61L2300/20; A61L2300/23; A61L2300/236
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
21 words
A composition of matter comprising poly (2-hydroxy ethyl methacrylate) modified by the inclusion therein of hyaluronic acid or a salt thereof.
Claim 2
Dependent Claim
21 words
A composition of matter comprising poly (2-hydroxy ethyl methacrylate) modified by the inclusion therein of hyaluronic acid or a salt thereof.
Claim 3
Dependent Claim
24 words
A composition according to claim 1 wherein the included hyaluronic acid is distributed throughout the body and on the surface of the polymeric material.
Claim 4
Dependent Claim
19 words
A composition according to claim 2 wherein the hyaluronic acid on the surface of the polymeric material is cross-linked.
Claim 5
Dependent Claim
11 words
A formed article made from the composition according to claim 1.
Claim 6
Dependent Claim
17 words
An article according to claim 4 which is a casting, a film, a fiber or a fabric.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-12-11 | 1988-06-11 | 1988-12-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-12-11 | 1992-06-11 | 1992-12-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-12-11 | 1996-06-11 | 1996-12-11 | $7700.00 | Window Closed / Lapsed |