Patent US4018999A successfully refreshed from Google Patents.
Patent EP0604022A1 successfully refreshed from Google Patents.
EP0604022A1
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Multilayered biodegradable stent and method for its manufacture
Assignee: Abbott Cardiovascular Systems Inc
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Filing: 1993-11-24
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Granted: —
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Expires: 2013-11-24
Abstract
Abstract A stent (12) of multilayered luminated construction wherein one layer (18) addresses the structural requirements of the stent and additional layers (20,22) release drugs at predictable rates. Both the structural layer (18) as well as the drug releasing layers (20,22) are eventually completely resorbed by the body.
Inventors
- 👤 Robert P. Eury
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 12:04
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/92; A61L; A61L31/00; A61L31/14; A61L31/148; A61L31/16; A61F2/02; A61F2/04; A61F2/06; A61F2/07; A61F2002/072; A61F2210/00; A61F2210/0004; A61F2210/0076; A61F2250/00; A61F2250/0058; A61F2250/0067
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
78 words
An expandable intraluminal stent for implantation in a vessel, comprising: a first layer formed of resorbable material selected to impart structural rigidity to said stent; and a second layer of a resorbable material, joined to said first layer and selected to release a therapeutic drug at a selected rate therefrom, whereby upon implantation, said stent initially provides a desired degree of structural support to said vessel, releases said drug at the selected rate and eventually is completely resorbed.
Claim 2
Dependent Claim
23 words
A stent as claimed in claim 1, wherein said first layer is further selected to impart additional desired physical characteristics to said stent.
Claim 3
Dependent Claim
17 words
A stent as claimed in claim 1, wherein said first layer comprises poly-L-lactic acid, or polyglycolic acid.
Claim 4
Dependent Claim
21 words
A stent as claimed in any one of claims 1 to 3, wherein said second layer comprises poly-DL-lactic acid or polycaprolactone.
Claim 5
Dependent Claim
35 words
A stent as claimed in any one of the preceding claims wherein said stent is implantable in a lumen upstream from a cancerous growth and said second layer is selected to release a chemotherapeutic drug.
Claim 6
Dependent Claim
20 words
A stent as claimed in any one of the preceding claims wherein said second layer is selected to release heparin.
Claim 7
Dependent Claim
64 words
A stent as claimed in any one of the preceding claims wherein a third layer of resorbable material is joined to said first layer and selected to release a therapeutic drug at a selected rate therefrom, whereby upon implantation, said stent initially provides a desired degree of structural support to said vessel, releases said drugs at the selected rates and eventually is completely resorbed.
Claim 8
Dependent Claim
19 words
A stent as claimed in claim 7, wherein the drugs released by said first and second layer are identical.
Claim 9
Dependent Claim
19 words
A stent as claimed in claim 7, wherein the drugs released by said first and second layer are different.
Claim 10
Dependent Claim
59 words
A stent as claimed in claim 9, wherein said stent is implantable within a coronary artery, said second layer is joined to the outer side of said stent's first layer and releases a drug that addresses restenosis and said third layer is joined to the inner side of said stent's first layer and releases a drug that addresses thrombosis.
Claim 11
Dependent Claim
25 words
A stent as claimed in claim 7, wherein said second layer is selected to release angiopeptin and said third layer is selected to release heparin.
Claim 12
Independent Claim
101 words
A method of fabricating a biodegradable, drug releasing stent for implantation within a lumen, comprising the steps of: forming a first layer of biodegradable material having physical properties necessary to enable a stent to perform its structural function within said lumen; forming a second layer of biodegradable material which releases a selected drug upon exposure to an environment such as is encountered within said lumen; and joining said second layer to said first layer to provide a laminated structure that is biodegradable, drug releasing and has the physical properties necessary for said stent to perform its structural function within said lumen.
Claim 13
Dependent Claim
45 words
A method as claimed in claim 12, further comprising the steps of: forming a third layer of biodegradable material which releases a selected drug upon exposure to an environment such as is encountered within said lumen; and joining said third layer to said first layer.
Claim 14
Dependent Claim
24 words
A method as claimed in claim 12 or claim 13, wherein said first layer is formed by extrusion and orientation of a polymeric material.
Claim 15
Dependent Claim
17 words
A method as claimed in claim 14, wherein said polymeric material comprises poly-L-lactic acid or polyglycolic acid.
Claim 16
Independent Claim
26 words
A method as claimed in any one of claims 12 to 15, wherein said second layer comprises a mixture of said drug and a polymeric material.
Claim 17
Dependent Claim
17 words
A method as claimed in claim 16, wherein said polymeric material comprises poly-DL-lactic acid or a polycaprolactone.
Claim 18
Independent Claim
33 words
A method as claimed in any one of claims 12 to 17, wherein said second layer is joined to said first layer with the application of heat or with the use of solvents.
Claim 19
Independent Claim
35 words
A method as claimed in any one of claims 13 to 17, wherein said second and third layers are joined to said first layer with the application of heat or with the use of solvents.
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