Patent US3233411A successfully refreshed from Google Patents.
US6991643B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
Multi-barbed device for retaining tissue in apposition and methods of use
Assignee: USGI Medical Inc
•
Filing: 2000-12-20
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Granted: 2006-01-31
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Expires: 2020-12-20
Abstract
Abstract A multi-barbed apparatus is provided, and methods of use, for penetrating two sides of a wound and holding the edges in apposition. The apparatus may be inserted within a wound or underneath the skin, and mechanically adheres the two sides of the wound together. The apparatus includes a biocompatible substrate carrying a multiplicity of tissue penetrating barbs on a least one side thereof, and may be formed as a rigid or flexible sheet, tube or other shape.
Inventors
- 👤 Vahid Saadat
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:35
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/44; A61F2/4455; A61B; A61B17/00; A61B17/08; A61B17/11; A61F2/0063; A61F2/04; A61F2/06; A61F2/064; A61F2/08; A61F2/30756; A61F2/442; A61F2/46; A61F2/4603; A61F2/4618; A61L; A61L31/00; A61L31/14; A61L31/16; A61B2017/00004; A61B2017/081; A61B2017/1103; A61F2/30767; A61F2/38; A61F2/389; A61F2/30771; A61F2002/30772; A61F2002/30784; A61F2002/30841; A61F2002/30878; A61F2002/30891; A61F2002/30892; A61F2002/30894; A61F2002/4625; A61F2002/4628; A61F2002/4635; A61F2002/4681; A61F2310/00; A61F2310/00389; A61F2310/00592; A61F2310/00796; A61F2310/00976; A61L2300/00; A61L2300/40; A61L2300/412; A61L2300/414; A61L2300/418
Claims Analysis
Total Claims: 54
Claim 1
Independent Claim
55 words
Apparatus for closing a wound comprising: a first elongated substrate including first and second surfaces; and a second elongated substrate including first and second surfaces, wherein the second surfaces are configured to mate with each other, wherein the first surfaces are covered by a multiplicity of barbs configured to adhere for adhering to the wound.
Claim 2
Dependent Claim
55 words
Apparatus for closing a wound comprising: a first elongated substrate including first and second surfaces; and a second elongated substrate including first and second surfaces, wherein the second surfaces are configured to mate with each other, wherein the first surfaces are covered by a multiplicity of barbs configured to adhere for adhering to the wound.
Claim 3
Dependent Claim
16 words
The apparatus of claim 1 , wherein the multiplicity of barbs projects from the first surface.
Claim 4
Dependent Claim
28 words
The apparatus of claim 2 , wherein each elongated substrate further comprises portions defining a plurality of perforations that extend from the first surface to the second surface.
Claim 5
Dependent Claim
14 words
The apparatus of claim 3 , wherein the plurality of perforations define suture eyelets.
Claim 6
Dependent Claim
18 words
The apparatus of claim 1 , wherein each elongated substrate further comprises a coating of a therapeutic agent.
Claim 7
Dependent Claim
16 words
The apparatus of claim 1 , wherein each elongated substrate is impregnated with a therapeutic agent.
Claim 8
Dependent Claim
18 words
The apparatus of claim 1 further comprising a therapeutic agent selected from a family of angiogenic growth factors.
Claim 9
Dependent Claim
18 words
The apparatus of claim 1 , wherein the first and second surfaces are tied together using a suture.
Claim 10
Dependent Claim
18 words
The apparatus of claim 1 , wherein each elongated substrate comprises a series of units interconnected by joints.
Claim 11
Independent Claim
86 words
A method for performing an anastomosis comprising: providing a device comprising an elongated tubular substrate of a biocompatible material having a first surface coated or impregnated with a therapeutic agent, multiple rows of barbs projecting from the first surface; positioning the elongated substrate within a wound so that the multiplicity of barbs is directed towards the tissue defining a perimeter of the wound; and squeezing the perimeter of the wound against the multiplicity of barbs to adhere the perimeter of the wound to the elongated substrate.
Claim 12
Independent Claim
86 words
A method for performing an anastomosis comprising: providing a device comprising an elongated tubular substrate of a biocompatible material having a first surface coated or impregnated with a therapeutic agent, multiple rows of barbs projecting from the first surface; positioning the elongated substrate within a wound so that the multiplicity of barbs is directed towards the tissue defining a perimeter of the wound; and squeezing the perimeter of the wound against the multiplicity of barbs to adhere the perimeter of the wound to the elongated substrate.
Claim 13
Dependent Claim
24 words
The method of claim 10 further comprising, during wound healing, releasing a predetermined amount of the therapeutic agent into the vicinity of the wound.
Claim 14
Independent Claim
180 words
A method for closing a tissue wound comprising: providing a device comprising first and second elongated substrate halves, each of the first and second elongated substrate halves comprising a biocompatible material having a first surface and a multiplicity of barbs projecting from the first surface; positioning the first elongated substrate half within a wound so that the multiplicity of barbs is directed towards the tissue defining a first portion of the perimeter of the wound; squeezing the first portion of the perimeter of the wound against the multiplicity of barbs to adhere the first portion of the perimeter of the wound to the first elongated substrate half; positioning the second elongated substrate half within the wound so that the multiplicity of barbs is directed towards the tissue defining a second portion of the perimeter of the wound; and squeezing the second portion of the perimeter of the wound against the multiplicity of barbs to adhere the second portion of the perimeter of the wound to the second elongated substrate half; and moving the first and second substrate halves into apposition.
Claim 15
Independent Claim
180 words
A method for closing a tissue wound comprising: providing a device comprising first and second elongated substrate halves, each of the first and second elongated substrate halves comprising a biocompatible material having a first surface and a multiplicity of barbs projecting from the first surface; positioning the first elongated substrate half within a wound so that the multiplicity of barbs is directed towards the tissue defining a first portion of the perimeter of the wound; squeezing the first portion of the perimeter of the wound against the multiplicity of barbs to adhere the first portion of the perimeter of the wound to the first elongated substrate half; positioning the second elongated substrate half within the wound so that the multiplicity of barbs is directed towards the tissue defining a second portion of the perimeter of the wound; and squeezing the second portion of the perimeter of the wound against the multiplicity of barbs to adhere the second portion of the perimeter of the wound to the second elongated substrate half; and moving the first and second substrate halves into apposition.
Claim 16
Dependent Claim
34 words
The method of claim 12 wherein moving the first and second substrate halves into apposition comprises threading suture material through eyelets in the first and second elongated substrate halves and knotting the suture material.
Claim 17
Dependent Claim
88 words
Apparatus for closing a wound comprising: an elongated substrate comprising a biocompatible material, the elongated substrate having a first and a second surface, a plurality of perforations extending from the first surface and adapted to define suture eyelets; and multiple rows of barbs projecting from the first and second surfaces, wherein the multiple rows of barbs have having tissue-penetrating distal ends; a plurality of perforations extending from the first surface and adapted to define suture eyelets; and suture extending through at least one of the plurality of perforations.
Claim 18
Dependent Claim
88 words
Apparatus for closing a wound comprising: an elongated substrate comprising a biocompatible material, the elongated substrate having a first and a second surface, a plurality of perforations extending from the first surface and adapted to define suture eyelets; and multiple rows of barbs projecting from the first and second surfaces, wherein the multiple rows of barbs have having tissue-penetrating distal ends; a plurality of perforations extending from the first surface and adapted to define suture eyelets; and suture extending through at least one of the plurality of perforations.
Claim 19
Dependent Claim
18 words
The apparatus of claim 14 , wherein the elongated substrate further comprises a coating of a therapeutic agent.
Claim 20
Dependent Claim
16 words
The apparatus of claim 14 , wherein the elongated substrate is impregnated with a therapeutic agent.
Claim 21
Dependent Claim
28 words
The apparatus of claim 14 , wherein each barb includes a shank coupling the tissue-penetrating distal end to the substrate, and one or more projections from the shank.
Claim 22
Dependent Claim
14 words
The apparatus of claim 17 , wherein each barb is cut from the substrate.
Claim 23
Dependent Claim
16 words
The apparatus of claim 14 , wherein the elongated substrate has the form of a tube.
Claim 24
Dependent Claim
18 words
The apparatus of claim 19 , wherein the tube includes an interior lumen formed by the first surface.
Claim 25
Dependent Claim
17 words
The apparatus of claim 19 , wherein the tube includes an exterior surface forming the first surface.
Claim 26
Dependent Claim
22 words
The apparatus of claim 14 further comprising a stent-like structure, wherein the elongated substrate forms a side anastomosis site of the apparatus.
Claim 27
Dependent Claim
18 words
The apparatus of claim 14 , wherein the elongated substrate comprises a series of units interconnected by joints.
Claim 28
Dependent Claim
17 words
The apparatus of claim 14 further comprising a region of artificial cartilage coupled to the elongated substrate.
Claim 29
Dependent Claim
16 words
The apparatus of claim 14 further comprising a replacement intervertebral disc coupled to the elongated substrate.
Claim 30
Dependent Claim
64 words
Apparatus for closing a wound comprising: an elongated substrate comprising a biocompatible material and impregnated with a therapeutic agent, the elongated substrate having a first surface; and multiple rows of barbs projecting from the first surface, the multiple rows of barbs having tissue-penetrating distal ends, wherein the elongated substrate has the form of a tube comprising an interior lumen formed by the first surface.
Claim 31
Dependent Claim
64 words
Apparatus for closing a wound comprising: an elongated substrate comprising a biocompatible material and impregnated with a therapeutic agent, the elongated substrate having a first surface; and multiple rows of barbs projecting from the first surface, the multiple rows of barbs having tissue-penetrating distal ends, wherein the elongated substrate has the form of a tube comprising an interior lumen formed by the first surface.
Claim 32
Dependent Claim
18 words
The apparatus of claim 26 , wherein the elongated substrate further comprises a coating of the therapeutic agent.
Claim 33
Dependent Claim
28 words
The apparatus of claim 26 , wherein each barb includes a shank coupling the tissue-penetrating distal end to the substrate, and one or more projections from the shank.
Claim 34
Dependent Claim
14 words
The apparatus of claim 28 , wherein each barb is cut from the substrate.
Claim 35
Dependent Claim
22 words
The apparatus of claim 26 further comprising a stent-like structure, wherein the elongated substrate forms a side anastomosis site of the apparatus.
Claim 36
Dependent Claim
64 words
Apparatus for closing a wound comprising: an elongated substrate comprising a biocompatible material and impregnated with a therapeutic agent, the elongated substrate having a first surface; and multiple rows of barbs projecting from the first surface, the multiple rows of barbs having tissue-penetrating distal ends, wherein the elongated substrate has the form of a tube comprising an exterior surface formed by the first surface.
Claim 37
Dependent Claim
64 words
Apparatus for closing a wound comprising: an elongated substrate comprising a biocompatible material and impregnated with a therapeutic agent, the elongated substrate having a first surface; and multiple rows of barbs projecting from the first surface, the multiple rows of barbs having tissue-penetrating distal ends, wherein the elongated substrate has the form of a tube comprising an exterior surface formed by the first surface.
Claim 38
Dependent Claim
18 words
The apparatus of claim 31 , wherein the elongated substrate further comprises a coating of the therapeutic agent.
Claim 39
Dependent Claim
28 words
The apparatus of claim 31 , wherein each barb includes a shank coupling the tissue-penetrating distal end to the substrate, and one or more projections from the shank.
Claim 40
Dependent Claim
14 words
The apparatus of claim 33 , wherein each barb is cut from the substrate.
Claim 41
Dependent Claim
22 words
The apparatus of claim 31 further comprising a stent-like structure, wherein the elongated substrate forms a side anastomosis site of the apparatus.
Claim 42
Dependent Claim
47 words
Apparatus for repairing cartilage comprising: an elongated substrate comprising a biocompatible material, the elongated substrate having a first surface, a multiplicity of barbs projecting from the first surface, the multiplicity of barbs having tissue-penetrating distal ends; and a region of artificial cartilage coupled to the elongated substrate.
Claim 43
Dependent Claim
47 words
Apparatus for repairing cartilage comprising: an elongated substrate comprising a biocompatible material, the elongated substrate having a first surface, a multiplicity of barbs projecting from the first surface, the multiplicity of barbs having tissue-penetrating distal ends; and a region of artificial cartilage coupled to the elongated substrate.
Claim 44
Dependent Claim
18 words
The apparatus of claim 36 , wherein the elongated substrate further comprises a coating of a therapeutic agent.
Claim 45
Dependent Claim
16 words
The apparatus of claim 36 , wherein the elongated substrate is impregnated with a therapeutic agent.
Claim 46
Dependent Claim
33 words
The apparatus of claim 36 , wherein each one of the multiplicity of barbs includes a shank coupling the tissue-penetrating distal end to the substrate, and one or more projections from the shank.
Claim 47
Dependent Claim
16 words
The apparatus of claim 39 , wherein the multiplicity of barbs are cut from the substrate.
Claim 48
Dependent Claim
48 words
Apparatus for repairing an intervertebral disc comprising: an elongated substrate comprising a biocompatible material, the elongated substrate having a first surface, a multiplicity of barbs projecting from the first surface, the multiplicity of barbs having tissue-penetrating distal ends; and a replacement intervertebral disc coupled to the elongated substrate.
Claim 49
Dependent Claim
48 words
Apparatus for repairing an intervertebral disc comprising: an elongated substrate comprising a biocompatible material, the elongated substrate having a first surface, a multiplicity of barbs projecting from the first surface, the multiplicity of barbs having tissue-penetrating distal ends; and a replacement intervertebral disc coupled to the elongated substrate.
Claim 50
Dependent Claim
18 words
The apparatus of claim 41 , wherein the elongated substrate further comprises a coating of a therapeutic agent.
Claim 51
Dependent Claim
16 words
The apparatus of claim 41 , wherein the elongated substrate is impregnated with a therapeutic agent.
Claim 52
Dependent Claim
33 words
The apparatus of claim 41 , wherein each one of the multiplicity of barbs includes a shank coupling the tissue-penetrating distal end to the substrate, and one or more projections from the shank.
Claim 53
Dependent Claim
16 words
The apparatus of claim 44 , wherein the multiplicity of barbs are cut from the substrate.
Claim 54
Dependent Claim
17 words
The apparatus of claim 41 further comprising a region of artificial cartilage coupled to the elongated substrate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2009-01-30 | 2009-08-01 | 2010-01-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2013-01-30 | 2013-08-01 | 2014-01-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2017-01-30 | 2017-08-01 | 2018-01-31 | $7700.00 | Window Closed / Lapsed |