US6355030B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Instruments and methods employing thermal energy for the repair and replacement of cardiac valves
Assignee: Recor Medical Inc
•
Filing: 1998-09-25
•
Granted: 2002-03-12
•
Expires: 2018-09-25
Abstract
Abstract The present invention is methods and devices for improving valve function in a heart. Particularly a device of the present invention comprises a an elongate member having a distal end and a proximal end, a thermal heating member fixed to the distal end of the elongate member, wherein the thermal heating member includes at least one thermal heating element adapted to supply thermal energy to a heart valve structure, and an energy source in communication with the thermal heating element. In use, a thermal heating device of the present invention is inserted into working space proximate the valve to be treated and is used to selectively contract the collagen fibers of the valve structure treated so as to improve the performance and functioning of the valve. Devices are disclosed suitable for use with a variety of access procedures on both beating and non-beating hearts, including: a minimally invasive surgical procedure, a sternotomy, a thoracotomy, an endovascular procedure, and endoscopic procedure, or a percutaneous procedure. Methods and devices are disclosed which are suitable for treatment of a chordae, leaflet, or annulus, as well as devices and methods for the replacement of heart valve with prosthetic valves.
Inventors
- 👤 William N. Aldrich
- 👤 Michael V. Morejohn
- 👤 Richard A. Helkowski
- 👤 Ivan Sepetka
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 20:20
CPC Classifications
A; A61; A61B; A61B18/00; A61B18/04; A61B18/08; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2427; A61B17/00; A61B2017/00017; A61B2017/00022; A61B2017/00084; A61B17/00234; A61B2017/00238; A61B2017/00243; A61B2018/044; A61B2018/046; A61B90/00; A61B90/30; A61F2/2412; A61F2/2442; A61F2/2445; A61F2/2463; A61F2250/00; A61F2250/0058; A61F2250/0059
Claims Analysis
Total Claims: 122
Claim 1
Independent Claim
108 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concave configuration shaped and proportioned to encompass generally oppositely disposed sides of the structure to be treated fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 2
Independent Claim
108 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concave configuration shaped and proportioned to encompass generally oppositely disposed sides of the structure to be treated fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 3
Dependent Claim
23 words
The apparatus of claim 1 wherein the at least one thermal heating element is an electrode in electrical communication with the energy source.
Claim 4
Dependent Claim
20 words
The apparatus of claim 1 wherein the thermal heating member includes a transverse groove sized to accommodate a valve chordae.
Claim 5
Dependent Claim
22 words
The apparatus of claim 1 including an integrally formed endoscope adapted to visualize an area of interest of the heart valve structure.
Claim 6
Dependent Claim
29 words
The apparatus of claim 1 wherein the elongate member includes a vacuum lumen in vacuum communication with a vacuum port disposed on the distal end of the elongate member.
Claim 7
Dependent Claim
21 words
The apparatus of claim 5 including a fiber-optic illuminator adapted to illuminate an area of interest on the heart valve structure.
Claim 8
Dependent Claim
25 words
The apparatus of claim 1 including a controller configured to selectively control the intensity and duration of thermal energy supplied to the thermal heating element.
Claim 9
Dependent Claim
19 words
The apparatus of claim 1 including a temperature sensor adapted to monitor the temperature of the thermal heating element.
Claim 10
Dependent Claim
46 words
The apparatus of claim 8 including a feedback control device configured to receive temperature data from the temperature sensor and adjust the supply of energy to the thermal heating element so as to maintain the temperature of the thermal heating element within a preselected temperature range.
Claim 11
Dependent Claim
16 words
The apparatus of claim 9 wherein the preselected temperature range is from 40° to 90° Celsius.
Claim 12
Dependent Claim
21 words
The apparatus of claim 1 including a lumen configured to supply conductive fluid to a heart valve structure to be treated.
Claim 13
Dependent Claim
20 words
The apparatus of claim 1 wherein the thermal heating member comprises a hook member sized to engage a valve chordae.
Claim 14
Dependent Claim
11 words
The apparatus of claim 12 wherein the hook member is conformable.
Claim 15
Dependent Claim
23 words
The apparatus of claim 1 wherein the elongate member and the thermal member are configured to be disposed within a trocar insertion sleeve.
Claim 16
Dependent Claim
27 words
The apparatus of claim 14 wherein the thermal heating member comprises a flexible panel member configured to be rolled lengthwise when disposed within the trocar insertion sleeve.
Claim 17
Dependent Claim
34 words
The apparatus of claim 14 wherein the elongate member includes a steering means located at the proximal end of the elongate member configured to manipulate at least the distal end of the elongate member.
Claim 18
Dependent Claim
25 words
The apparatus of claim 1 wherein the elongate member comprises a flexible cannula configured for endovascular insertion of the elongate member through a body vessel.
Claim 19
Dependent Claim
13 words
The apparatus of claim 1 wherein the elongate member comprises an elongate wand.
Claim 20
Dependent Claim
23 words
The apparatus of claim 1 wherein the at least one heating element is located on an inner surface of the thermal heating member.
Claim 21
Independent Claim
93 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 22
Independent Claim
93 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 23
Dependent Claim
22 words
The apparatus of claim 20 wherein the thermal heating member comprises an annular configuration sized to approximate the circumference of an annulus.
Claim 24
Dependent Claim
18 words
The apparatus of claim 21 wherein the annular configuration has a circumference of between 8.5 to 10 cm.
Claim 25
Dependent Claim
12 words
The apparatus of claim 21 wherein the thermal heating member is conformable.
Claim 26
Dependent Claim
21 words
The apparatus of claim 21 wherein the apparatus is adapted to be endovascularly delivered proximate the valve structure to be treated.
Claim 27
Dependent Claim
29 words
The apparatus of claim 21 wherein the at least one thermal heating element comprises a plurality of thermal heating elements disposed about a circumference of the thermal heating member.
Claim 28
Dependent Claim
16 words
The apparatus of claim 21 wherein the annular configuration is concentrically disposed about the elongate member.
Claim 29
Dependent Claim
35 words
The apparatus of claim 26 including a plurality of arms circumferentially fixed at a first end about the distal end of the elongate member and circumferentially fixed at a second end to the annular configuration.
Claim 30
Dependent Claim
38 words
The apparatus of claim 26 including a fluid impermeable membrane fluidly sealing a cross sectional area of the thermal heating member defined by an inner circumference of the annular configuration and an outer circumference of the elongate member.
Claim 31
Dependent Claim
15 words
The apparatus of claim 26 wherein the annular configuration is collapsible about the elongate member.
Claim 32
Dependent Claim
19 words
The apparatus of claim 26 including a trocar insertion sleeve adapted to be slidingly disposed about the annular configuration.
Claim 33
Dependent Claim
117 words
The apparatus of claim 20 wherein the heating member comprises: a centrally disposed perfusion tube having a perfusion lumen therethrough, the perfusion lumen fluidly connecting at least one perfusion port formed in a wall of the perfusion tube with a distal end of the perfusion lumen; an annular configuration concentrically disposed about the perfusion tube and sized to approximate the circumference of an annulus, wherein the at least one thermal heating element comprises a plurality of thermal heating elements disposed about a circumference of the annular configuration; and a fluid impermeable membrane adapted to fluidly seal a cross sectional area defined by an inner circumference of the annular configuration and an outer circumference of the perfusion tube.
Claim 34
Dependent Claim
33 words
The apparatus of claim 31 wherein the perfusion lumen includes a one-way valve configured to prevent fluid flow from the distal end of the perfusion lumen to the at least one perfusion port.
Claim 35
Dependent Claim
15 words
The apparatus of claim 31 including an insertion catheter slidingly disposed about the perfusion tube.
Claim 36
Dependent Claim
15 words
The apparatus of claim 31 wherein the annular configuration is contractible about the perfusion tube.
Claim 37
Dependent Claim
67 words
The apparatus of claim 33 including a plurality of proximal arm members, each proximal arm member having a proximal end fixed to a distal end of the insertion catheter and a distal end fixed to the annular configuration, and a plurality of distal arm members, each distal arm member having a distal end fixed to the perfusion tube and a proximal end fixed to the annular configuration.
Claim 38
Dependent Claim
23 words
The apparatus of claim 20 wherein the at least one thermal heating element is an electrode in electrical communication with the energy source.
Claim 39
Dependent Claim
22 words
The apparatus of claim 20 including an integrally formed endoscope adapted to visualize an area of interest of the heart valve structure.
Claim 40
Dependent Claim
29 words
The apparatus of claim 20 wherein the elongate member includes a vacuum lumen in vacuum communication with a vacuum port disposed on the distal end of the elongate member.
Claim 41
Dependent Claim
21 words
The apparatus of claim 38 including a fiber-optic illuminator adapted to illuminate an area of interest on the heart valve structure.
Claim 42
Dependent Claim
25 words
The apparatus of claim 20 including a controller configured to selectively control the intensity and duration of thermal energy supplied to the thermal heating element.
Claim 43
Dependent Claim
19 words
The apparatus of claim 20 including a temperature sensor adapted to monitor the temperature of the thermal heating element.
Claim 44
Dependent Claim
46 words
The apparatus of claim 41 including a feedback control device configured to receive temperature data from the temperature sensor and adjust the supply of energy to the thermal heating element so as to maintain the temperature of the thermal heating element within a preselected temperature range.
Claim 45
Dependent Claim
16 words
The apparatus of claim 42 wherein the preselected temperature range is from 40° to 90° Celsius.
Claim 46
Dependent Claim
21 words
The apparatus of claim 20 including a lumen configured to supply conductive fluid to a heart valve structure to be treated.
Claim 47
Dependent Claim
23 words
The apparatus of claim 20 wherein the elongate member and the thermal member are configured to be disposed within a trocar insertion sleeve.
Claim 48
Dependent Claim
34 words
The apparatus of claim 45 wherein the elongate member includes a steering means located at the proximal end of the elongate member configured to manipulate at least the distal portion of the elongate member.
Claim 49
Dependent Claim
25 words
The apparatus of claim 20 wherein the elongate member comprises a flexible cannula configured for endovascular insertion of the elongate member through a body vessel.
Claim 50
Dependent Claim
13 words
The apparatus of claim 20 wherein the elongate member comprises an elongate wand.
Claim 51
Dependent Claim
23 words
The apparatus of claim 20 wherein the at least one heating element is located on an inner surface of the thermal heating member.
Claim 52
Independent Claim
162 words
A method of treating a heart valve stricture comprising: providing a working space proximate a heart valve structure; and providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concave configuration shaped and proportioned to encompass generally oppositely disposed sides of the structure to be treated fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 53
Independent Claim
162 words
A method of treating a heart valve stricture comprising: providing a working space proximate a heart valve structure; and providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concave configuration shaped and proportioned to encompass generally oppositely disposed sides of the structure to be treated fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 54
Dependent Claim
46 words
The method of claim 50 wherein elongate member comprises a wand member configured to be percutaneously delivered to a region of interest proximate the heart valve structure, the step of providing a working space proximate the heart valve structure comprising performing a beating-heart endovascular access procedure.
Claim 55
Dependent Claim
31 words
The method of claim 50 wherein the step of contacting the valve structure with the thermal heating element of the thermal heating member comprises contacting an annulus of the heart valve.
Claim 56
Dependent Claim
22 words
The method of claim 52 wherein the step of selectively contracting the annulus causes a reduction in the circumference of the annulus.
Claim 57
Dependent Claim
32 words
The method of claim 50 including the additional step of monitoring the functioning of the heart valve with a monitoring device substantially simultaneously with providing thermal energy to the heart valve structure.
Claim 58
Dependent Claim
34 words
The method of claim 54 wherein the monitoring device comprises a transesophegial echocardiography device, the method including the additional step of installing the device so as to monitor the functioning of the heart valve.
Claim 59
Dependent Claim
53 words
The method of claim 50 wherein the step of providing a working space proximate the heart valve structure comprises performing an access procedure chosen from the group consisting of: a thoracotomy, a sternotomy, a mini-thoracotomy, a mini-sternotomy, a sub-xyphoid access procedure, a xyphoid access procedure, a thorascopic procedure, and an endovascular access procedure.
Claim 60
Dependent Claim
30 words
The method of claim 50 including the additional step of placing the heart on cardiopulmonary bypass prior to the step of providing a working space proximate the heart valve structure.
Claim 61
Dependent Claim
38 words
The method of claim 50 including the additional step of providing a thermally conductive fluid to at least a portion of the heart valve structure prior to the step of providing thermal energy from the thermal heating element.
Claim 62
Independent Claim
147 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; and providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 63
Independent Claim
147 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; and providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 64
Dependent Claim
45 words
The method of claim 59 wherein elongate member comprises a wand member to be percutaneously delivered to a region of interest proximate the heart valve structure, the step of providing a working space proximate the heart valve structure comprising performing a beating-heart endovascular access procedure.
Claim 65
Dependent Claim
30 words
The method of claim 59 wherein the step of contacting the valve structure with the thermal heating element of the thermal member comprises contacting an annulus of the heart valve.
Claim 66
Dependent Claim
22 words
The method of claim 61 wherein the step of selectively contracting the annulus causes a reduction in the circumference of the annulus.
Claim 67
Dependent Claim
32 words
The method of claim 59 including the additional step of monitoring the functioning of the heart valve with a monitoring device substantially simultaneously with providing thermal energy to the heart valve structure.
Claim 68
Dependent Claim
35 words
The method of claim 63 , wherein the monitoring device comprises a transesophegial echocardiography device, the method including the additional step of installing the device so as to monitor the functioning of the heart valve.
Claim 69
Dependent Claim
53 words
The method of claim 59 wherein the step of providing a working space proximate the heart valve structure comprises performing an access procedure chosen from the group consisting of: a thoracotomy, a sternotomy, a mini-thoracotomy, a mini-sternotomy, a sub-xyphoid access procedure, a xyphoid access procedure, a thorascopic procedure, and an endovascular access procedure.
Claim 70
Dependent Claim
30 words
The method of claim 59 including the additional step of placing the heart on cardiopulmonary bypass prior to the step of providing a working space proximate the heart valve structure.
Claim 71
Dependent Claim
38 words
The method of claim 59 including the additional step of providing a thermally conductive fluid to at least a portion of the heart valve structure prior to the step of providing thermal energy from the thermal heating element.
Claim 72
Independent Claim
111 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the thermal heating member includes a transverse groove sized to accommodate a valve chordae.
Claim 73
Independent Claim
111 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the thermal heating member includes a transverse groove sized to accommodate a valve chordae.
Claim 74
Independent Claim
112 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; a source of non-ablative energy in communication with the thermal heating element; and an integrally formed endoscope adapted to visualize the area of interest of the heart valve structure.
Claim 75
Independent Claim
112 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; a source of non-ablative energy in communication with the thermal heating element; and an integrally formed endoscope adapted to visualize the area of interest of the heart valve structure.
Claim 76
Independent Claim
120 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel, wherein the elongate member includes a vacuum lumen in vacuum communication with a vacuum port disposed on the distal end of the elongate member; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 77
Independent Claim
120 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel, wherein the elongate member includes a vacuum lumen in vacuum communication with a vacuum port disposed on the distal end of the elongate member; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 78
Dependent Claim
22 words
The apparatus of claim 70 , including a fiber-optic illuminator adapted to illuminate an area of interest on the heart valve structure.
Claim 79
Independent Claim
111 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; a source of non-ablative energy in communication with the thermal heating element; and a lumen configured to supply conductive fluid to a heart valve structure to be treated.
Claim 80
Independent Claim
111 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; a source of non-ablative energy in communication with the thermal heating element; and a lumen configured to supply conductive fluid to a heart valve structure to be treated.
Claim 81
Independent Claim
111 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member, wherein the thermal heating member comprises a hook member sized to engage a valve chordae; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 82
Independent Claim
111 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member, wherein the thermal heating member comprises a hook member sized to engage a valve chordae; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 83
Dependent Claim
11 words
The apparatus of claim 73 wherein the hook member is conformable.
Claim 84
Independent Claim
115 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the elongate member and the thermal heating member are configured to be disposed within a trocar insertion sleeve.
Claim 85
Independent Claim
115 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the elongate member and the thermal heating member are configured to be disposed within a trocar insertion sleeve.
Claim 86
Dependent Claim
27 words
The apparatus of claim 75 wherein the thermal heating member comprises a flexible panel member configured to be rolled lengthwise when disposed within the trocar insertion sleeve.
Claim 87
Dependent Claim
34 words
The apparatus of claim 75 wherein the elongate member includes a steering means located at the proximal end of the elongate member configured to manipulate at least the distal portion of the elongate member.
Claim 88
Independent Claim
113 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the thermal heating member comprises an annular configuration sized to approximate the circumference of an annulus.
Claim 89
Independent Claim
113 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the thermal heating member comprises an annular configuration sized to approximate the circumference of an annulus.
Claim 90
Dependent Claim
18 words
The apparatus of claim 78 wherein the annular configuration has a circumference of between 8.5 to 10 cm.
Claim 91
Dependent Claim
12 words
The apparatus of claim 78 wherein the thermal heating member is conformable.
Claim 92
Dependent Claim
21 words
The apparatus of claim 78 wherein the apparatus is adapted to be endovascularly delivered proximate the valve structure to be treated.
Claim 93
Dependent Claim
29 words
The apparatus of claim 78 wherein the at least one thermal heating element comprises a plurality of thermal heating elements disposed about a circumference of the thermal heating member.
Claim 94
Dependent Claim
16 words
The apparatus of claim 78 wherein the annular configuration is concentrically disposed about the elongate member.
Claim 95
Dependent Claim
35 words
The apparatus of claim 83 including a plurality of arms circumferentially fixed at a first end about the distal end of the elongate member and circumferentially fixed at a second end to the annular configuration.
Claim 96
Dependent Claim
38 words
The apparatus of claim 83 including a fluid impermeable membrane fluidly sealing a cross sectional area of the thermal heating member defined by an inner circumference of the annular configuration and an outer circumference of the elongate member.
Claim 97
Dependent Claim
15 words
The apparatus of claim 83 wherein the annular configuration is collapsible about the elongate member.
Claim 98
Dependent Claim
19 words
The apparatus of claim 83 including a trocar insertion sleeve adapted to be slidingly disposed about the annular configuration.
Claim 99
Independent Claim
208 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the heating member comprises a centrally disposed perfusion tube having a perfusion lumen therethrough, the perfusion lumen fluidly connecting at least one perfusion port formed in a wall of the perfusion tube with a distal end of the perfusion lumen, an annular configuration concentrically disposed about the perfusion tube and sized to approximate the circumference of an annulus, wherein the at least one thermal heating element comprises a plurality of thermal heating elements disposed about a circumference of the annular configuration, and a fluid impermeable membrane adapted to fluidly seal a cross sectional area defined by an inner circumference of the annular configuration and an outer circumference of the perfusion tube.
Claim 100
Independent Claim
208 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the heating member comprises a centrally disposed perfusion tube having a perfusion lumen therethrough, the perfusion lumen fluidly connecting at least one perfusion port formed in a wall of the perfusion tube with a distal end of the perfusion lumen, an annular configuration concentrically disposed about the perfusion tube and sized to approximate the circumference of an annulus, wherein the at least one thermal heating element comprises a plurality of thermal heating elements disposed about a circumference of the annular configuration, and a fluid impermeable membrane adapted to fluidly seal a cross sectional area defined by an inner circumference of the annular configuration and an outer circumference of the perfusion tube.
Claim 101
Dependent Claim
33 words
The apparatus of claim 88 wherein the perfusion lumen includes a one-way valve configured to prevent fluid flow from the distal end of the perfusion lumen to the at least one perfusion port.
Claim 102
Dependent Claim
15 words
The apparatus of claim 88 including an insertion catheter slidingly disposed about the perfusion tube.
Claim 103
Dependent Claim
67 words
The apparatus of claim 90 including a plurality of proximal arm members, each proximal arm member having a proximal end fixed to a distal end of the insertion catheter and a distal end fixed to the annular configuration, and a plurality of distal arm members, each distal arm member having a distal end fixed to the perfusion tube and a proximal end fixed to the annular configuration.
Claim 104
Dependent Claim
15 words
The apparatus of claim 88 wherein the annular configuration is contractible about the perfusion tube.
Claim 105
Independent Claim
192 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; and providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element, and the elongate member comprises a wand member configured to be percutaneously delivered to a region of interest proximate the heart valve structure, the step of providing a working space proximate the heart valve structure comprising performing a beating-heart endovascular access procedure.
Claim 106
Independent Claim
192 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; and providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element, and the elongate member comprises a wand member configured to be percutaneously delivered to a region of interest proximate the heart valve structure, the step of providing a working space proximate the heart valve structure comprising performing a beating-heart endovascular access procedure.
Claim 107
Independent Claim
172 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; and monitoring the functioning of the heart valve with a monitoring device substantially simultaneously with providing thermal energy to the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 108
Independent Claim
172 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; and monitoring the functioning of the heart valve with a monitoring device substantially simultaneously with providing thermal energy to the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 109
Dependent Claim
34 words
The method of claim 94 wherein the monitoring device comprises a transesophegial echocardiography device, the method including the additional step of installing the device so as to monitor the functioning of the heart valve.
Claim 110
Independent Claim
199 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; and providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element, and wherein the step of providing a working space proximate the heart valve structure comprises performing an access procedure chosen from the group consisting of: a thoracotomy, a sternotomy, a mini-thoracotomy, a mini-sternotomy, a sub-xyphoid access procedure, a xyphoid access procedure, a thorascopic procedure, and an endovascular access procedure.
Claim 111
Independent Claim
199 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; and providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element, and wherein the step of providing a working space proximate the heart valve structure comprises performing an access procedure chosen from the group consisting of: a thoracotomy, a sternotomy, a mini-thoracotomy, a mini-sternotomy, a sub-xyphoid access procedure, a xyphoid access procedure, a thorascopic procedure, and an endovascular access procedure.
Claim 112
Independent Claim
116 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the elongate member comprises a flexible cannula configured for endovascular insertion of the elongate member through a body vessel.
Claim 113
Independent Claim
116 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the elongate member comprises a flexible cannula configured for endovascular insertion of the elongate member through a body vessel.
Claim 114
Independent Claim
104 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the elongate member comprises an elongate wand.
Claim 115
Independent Claim
104 words
An apparatus for supplying non-ablative thermal energy to a heart valve structure comprising: an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element; wherein the elongate member comprises an elongate wand.
Claim 116
Independent Claim
177 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; and providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element, and wherein the step of contacting the valve structure with the thermal heating element of the thermal heating member comprises contacting an annulus of the heart valve.
Claim 117
Independent Claim
177 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; and providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element, and wherein the step of contacting the valve structure with the thermal heating element of the thermal heating member comprises contacting an annulus of the heart valve.
Claim 118
Dependent Claim
23 words
The method of claim 99 , wherein the step of selectively contracting the annulus causes a reduction in the circumference of the annulus.
Claim 119
Independent Claim
170 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; and placing the heart on cardiopulmonary bypass prior to the step of providing a working space proximate the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 120
Independent Claim
170 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; and placing the heart on cardiopulmonary bypass prior to the step of providing a working space proximate the heart valve structure; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 121
Independent Claim
178 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; and providing a thermally conductive fluid to at least a portion of the heart valve structure prior to the step of providing thermal energy from the thermal heating element; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
Claim 122
Independent Claim
178 words
A method of treating a heart valve structure comprising: providing a working space proximate a heart valve structure; providing non-ablative thermal energy to the heart valve structure so as to selectively contact at least a portion of the heart valve structure; and providing a thermally conductive fluid to at least a portion of the heart valve structure prior to the step of providing thermal energy from the thermal heating element; wherein said step of providing non-ablative thermal energy comprises inserting a thermal treatment apparatus into the working space proximate the structure, the thermal apparatus comprising an elongate member having a distal end and a proximal end, the elongate member configured to allow insertion of the elongate member into a body vessel; a thermal heating member having a generally concavedly curved or annular configuration fixed to the distal end of the elongate member; at least one thermal heating element adapted to supply non-ablative thermal energy to a heart valve structure disposed on the thermal heating member; and a source of non-ablative energy in communication with the thermal heating element.
References Cited (Backward Citations)
US4672962A
Cited
US5304176A
Cited
US5433708A
Cited
US5772590A
Cited
US5376087A
Cited
US5458596A
Cited
US5769846A
Cited
US5514130A
Cited
US5766234A
Cited
WO1998001076A1
Cited
WO1998018393A1
Cited
WO1998019613A1
Cited
WO1998026738A1
Cited
WO1998032382A1
Cited
US5928224A
Cited
WO1998035638A1
Cited
US5989284A
Cited
WO1998044854A1
Cited
US6267781B1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 2005-03-11 | 2005-09-10 | 2006-03-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2009-03-11 | 2009-09-10 | 2010-03-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2013-03-11 | 2013-09-10 | 2014-03-12 | $7700.00 | Window Closed / Lapsed |