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US6921410B2 Expired / Lapsed US ⏱️ 0.0 years remaining

Injection molded vaso-occlusive elements

Assignee: Stryker European Operations Holdings LLC
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Filing: 2001-05-29
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Granted: 2005-07-26
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Expires: 2021-05-29
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Abstract

Abstract Compositions comprising injection-molded vaso-occlusive elements are described. Thus, one or more injection-molded elements are formed into a desired three-dimensional configuration. Each injection-molded element of the device may have a different shape, for example, ovoid, spherical, cylindral or pyramidal. The devices described herein may also be detachable linked to pusher element for placement in a body cavity. Also described are methods of making and using these elements.

Inventors

  • 👤 Stephen Christopher Porter

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:49
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12131; A61B17/12163

Claims Analysis

Total Claims: 50
Claim 1
Independent Claim 49 words
A method for producing a vaso-occlusive element for use in occluding a vessel, the method comprising the step of injection molding an absorbable polymeric material into the three-dimensional configuration, wherein the three-dimensional configuration self-forms upon deployment or where the three-dimensional configuration does not change upon deployment into the vessel.
Claim 2
Independent Claim 49 words
A method for producing a vaso-occlusive element for use in occluding a vessel, the method comprising the step of injection molding an absorbable polymeric material into the three-dimensional configuration, wherein the three-dimensional configuration self-forms upon deployment or where the three-dimensional configuration does not change upon deployment into the vessel.
Claim 3
Dependent Claim 43 words
The method of claim 1 , wherein the absorbable material is selected from the group consisting of polyglycolide, poly-L-lactide, poly(g-ethyl glutamates, polyphosphazene, polysaccharides, polyorthoesters, polycaprolactone, polyhydroxybutyrate, polydioxanone, polycarbonates, polyanhydrides, copolymers or blends thereof, collagen, elastin, fibrinogen, fibronectin, vitronectin, laminin, gelatin and combinations thereof.
Claim 4
Dependent Claim 18 words
The method of claim 1 , wherein the three-dimensional configuration comprises a cylindrical configuration having a longitudinal axis.
Claim 5
Dependent Claim 17 words
The method of claim 3 , wherein the cylindrical configuration further includes a plurality of channels therein.
Claim 6
Dependent Claim 18 words
The method of claim 4 , wherein the channels are perpendicular to the longitudinal axis of the device.
Claim 7
Dependent Claim 19 words
The method of claim 1 , wherein the three-dimensional configuration comprises a plurality of shaped structures linked in series.
Claim 8
Dependent Claim 12 words
The method of claim 6 , wherein the shaped elements are ovoid.
Claim 9
Dependent Claim 12 words
The method of claim 6 , wherein the shaped elements are spherical.
Claim 10
Dependent Claim 14 words
The method of claim 6 , wherein the shaped elements are conical or pyramidal.
Claim 11
Dependent Claim 14 words
The method of claim 6 , wherein the three-dimensional configuration is a single-molded element.
Claim 12
Dependent Claim 18 words
The method of claim 6 , wherein the three-dimensional configuration is formed from two or more separate elements.
Claim 13
Dependent Claim 21 words
The method of claim 6 , wherein the separate elements are linked by a polymeric wire or a ductile metallic wire.
Claim 14
Dependent Claim 23 words
The method of claim 1 , further comprising the step of providing one or more severable junctions detachably connected to a pusher element.
Claim 15
Dependent Claim 27 words
The method of claim 13 , wherein the severable junction comprises an electrolytically detachable assembly adapted to detach by imposition of a current on said pusher element.
Claim 16
Dependent Claim 29 words
The method of claim 13 , wherein the severable junction comprises a mechanically detachable assembly adapted to detach by movement or pressure imposed on or within said pusher element.
Claim 17
Dependent Claim 26 words
The method of claim 13 , wherein the severable junction comprises a thermally detachable assembly adapted to detach by localized delivery of heat to said junction.
Claim 18
Dependent Claim 26 words
The method of claim 13 , wherein the severable junction comprises a radiation detachable assembly adapted to detach by delivery of electromagnetic radiation to said junction.
Claim 19
Dependent Claim 12 words
The method of claim 1 , further comprising micro-machining the injection-molded element.
Claim 20
Dependent Claim 13 words
The method of claim 1 , further comprising chemically etching the injection-molded element.
Claim 21
Dependent Claim 13 words
The method of claim 1 , further comprising laser cutting the injection-molded element.
Claim 22
Dependent Claim 15 words
The method of claim 1 , further comprising linking a plurality of the injection-molded elements.
Claim 23
Dependent Claim 32 words
The method of claim 21 , wherein the linking is by a method selected from the group consisting of soldering, interference fitting, friction fitting, stringing, ultrasonic welding, thermal welding and solvent bonding.
Claim 24
Dependent Claim 20 words
The method of claim 1 , further comprising the step of blending one or more radio-opaque materials with the polymer.
Claim 25
Dependent Claim 20 words
The method of claim 1 , wherein the injection molding comprises insert molding a metallic wire within the three-dimensional configuration.
Claim 26
Dependent Claim 11 words
A vaso-occlusive device produced by the method of claim 1 .
Claim 27
Dependent Claim 32 words
A vaso-occlusive device comprising at least one polymeric material, wherein said device is formed into a three-dimensional configuration and is adapted to be deployed into a body cavity in the three-dimensional configuration.
Claim 28
Dependent Claim 32 words
A vaso-occlusive device comprising at least one polymeric material, wherein said device is formed into a three-dimensional configuration and is adapted to be deployed into a body cavity in the three-dimensional configuration.
Claim 29
Dependent Claim 19 words
The vaso-occlusive device of claim 26 , wherein the vaso-occlusive device comprises at least one absorbable or biodegradable polymer.
Claim 30
Dependent Claim 43 words
The device of claim 27 , wherein the absorbable material is selected from the group consisting of polyglycolide, poly-L-lactide, poly(g-ethyl glutamates, polyphosphazene, polysaccharides, polyorthoesters, polycaprolactone, polyhydroxybutyrate, polydioxanone, polycarbonates, polyanhydrides, copolymers or blends thereof, collagen, elastin, fibrinogen, fibronectin, vitronectin, laminin, gelatin and combinations thereof.
Claim 31
Dependent Claim 18 words
The device of claim 26 , wherein the three-dimensional configuration comprises a cylindrical configuration having a longitudinal axis.
Claim 32
Dependent Claim 17 words
The device of claim 29 , wherein the cylindrical configuration further includes a plurality of channels therein.
Claim 33
Dependent Claim 18 words
The device of claim 30 , wherein the channels are perpendicular to the longitudinal axis of the device.
Claim 34
Dependent Claim 19 words
The device of claim 26 , wherein the three-dimensional configuration comprises a plurality of shaped structures linked in series.
Claim 35
Dependent Claim 12 words
The device of claim 32 , wherein the shaped elements are ovoid.
Claim 36
Dependent Claim 12 words
The device of claim 32 , wherein the shaped elements are spherical.
Claim 37
Dependent Claim 14 words
The device of claim 32 , wherein the shaped elements are conical or pyramidal.
Claim 38
Dependent Claim 14 words
The device of claim 32 , wherein the three-dimensional configuration is a single-molded element.
Claim 39
Dependent Claim 18 words
The device of claim 32 , wherein the three-dimensional configuration is formed from two or more separate elements.
Claim 40
Dependent Claim 21 words
The device of claim 32 , wherein the separate elements are linked by a polymeric wire or a ductile metallic wire.
Claim 41
Dependent Claim 20 words
The device of claim 26 , further comprising the step of providing severable junction detachably connected to a pusher element.
Claim 42
Dependent Claim 27 words
The device of claim 39 , wherein the severable junction comprises an electrolytically detachable assembly adapted to detach by imposition of a current on said pusher element.
Claim 43
Dependent Claim 29 words
The device of claim 39 , wherein the severable junction comprises a mechanically detachable assembly adapted to detach by movement or pressure imposed on or within said pusher element.
Claim 44
Dependent Claim 26 words
The device of claim 39 , wherein the severable junction comprises a thermally detachable assembly adapted to detach by localized delivery of heat to said junction.
Claim 45
Dependent Claim 26 words
The device of claim 39 , wherein the severable junction comprises a radiation detachable assembly adapted to detach by delivery of electromagnetic radiation to said junction.
Claim 46
Dependent Claim 11 words
The device of claim 26 , further comprising a radio-opaque material.
Claim 47
Dependent Claim 28 words
The device of claim 44 , where the radio-opaque material is selected from the group consisting of tantalum, tantalum oxide, tungsten, bismuth oxide, barium sulfate, platinum, and gold.
Claim 48
Dependent Claim 11 words
The device of claim 26 , further comprising a bioactive material.
Claim 49
Dependent Claim 10 words
The device of claim 26 , produced by injection molding.
Claim 50
Dependent Claim 11 words
The device of claim 47 , wherein the device is micro-machined.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2008-07-25 2009-01-24 2009-07-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2012-07-25 2013-01-24 2013-07-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2016-07-25 2017-01-24 2017-07-26 $7700.00 Window Closed / Lapsed

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