Patent FR2594322A1 successfully refreshed from Google Patents.
US6729334B1
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US
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Nebulizing catheter system and methods of use and manufacture
Assignee: Trudell Medical Ltd
•
Filing: 1999-03-10
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Granted: 2004-05-04
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Expires: 2019-03-10
Abstract
Abstract A method and apparatus for delivering a medicine to a patient via the patient's respiratory system with control and efficiency. A nebulization catheter is positioned in the patient's respiratory system so that a distal end of the nebulization catheter is in the respiratory system and a proximal end is outside the body. In a first aspect, the nebulization catheter may be used in conjunction with an endotracheal tube and preferably is removable from the endotracheal tube. The nebulization catheter conveys medicine in liquid form to the distal end at which location the medicine is nebulized by a pressurized gas or other nebulizing mechanism. The nebulized medicine is conveyed to the patient's lungs by the patient's respiration which may be assisted by a ventilator. By producing the aerosol of the liquid medicine at a location inside the patient's respiratory system, the nebulizing catheter provides for increased efficiency and control of the dosage of medicine being delivered. In further aspects of the nebulizing catheter apparatus and method, alternative tip constructions, flow pulsation patterns, centering devices, sensing devices, and aspiration features afford greater efficiency and control of aerosolized medicine dosage delivery.
Inventors
- 👤 George Baran
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:06
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/0021; A61M25/0023; A61M25/0026; A61M25/003; A61B; A61B90/00; A61B90/70; A61M11/00; A61M11/001; A61M11/005; A61M16/00; A61M16/04; A61M16/0402; A61M16/0404; A61M16/042; A61M16/0463; A61M16/0475; A61M16/0477; A61M16/0484; A61M16/0486; B; B67; B67D; B67D7/00; B67D7/06; A61M11/06; A61M15/00; A61M15/02; A61M15/025; A61M2025/0035; A61M2025/0036; A61M2025/0037; A61M2025/0039; A61M2025/004; A61M25/0067; A61M25/0068; A61M2025/0073; A61M2205/00; A61M2205/02; A61M2205/0266; A61M2209/00; A61M2209/10; A61M25/0009; A61M25/0071
Claims Analysis
Total Claims: 60
Claim 1
Independent Claim
120 words
A catheter for delivering an aerosol of medicine to a patient comprising: a catheter shaft having a proximal end and a distal end; a lumen through the catheter shaft and communicating at the proximal end with a port for receiving a medicine in a liquid form and communicating at the distal end with a distal orifice from which the medicine can be discharged; means for nebulizing the medicine discharged at the distal orifice into an aerosol plume of particles of the medicine; and means for modifying the aerosol plume of particles of medicine, wherein the modifying means comprises a vacuum orifice located close to the distal orifice from which the medicine is discharged for scavenging air from the nebulized aerosol.
Claim 2
Dependent Claim
120 words
A catheter for delivering an aerosol of medicine to a patient comprising: a catheter shaft having a proximal end and a distal end; a lumen through the catheter shaft and communicating at the proximal end with a port for receiving a medicine in a liquid form and communicating at the distal end with a distal orifice from which the medicine can be discharged; means for nebulizing the medicine discharged at the distal orifice into an aerosol plume of particles of the medicine; and means for modifying the aerosol plume of particles of medicine, wherein the modifying means comprises a vacuum orifice located close to the distal orifice from which the medicine is discharged for scavenging air from the nebulized aerosol.
Claim 3
Dependent Claim
152 words
A catheter system for delivering an aerosol of medicine to a patient comprising: a catheter shaft having a proximal end and a distal end; a lumen through the catheter shaft and communicating at the proximal end with a port for receiving a medicine in a liquid form and communicating at the distal end with a distal orifice from which the medicine can be discharged; means for nebulizing the medicine discharged at the distal orifice; and a flow control apparatus connected to the port, said flow control apparatus comprising: a flow line communicating with the port, said flow line occupied by the medicine; a valve associated with the flow line to cause pulsed delivery of medicine through the flow line; and a draw back area associated with the flow line, said draw back area adapted to cause a reversal of flow of medicine through the flow line controller synchronized with the pulsed delivery.
Claim 4
Dependent Claim
152 words
A catheter system for delivering an aerosol of medicine to a patient comprising: a catheter shaft having a proximal end and a distal end; a lumen through the catheter shaft and communicating at the proximal end with a port for receiving a medicine in a liquid form and communicating at the distal end with a distal orifice from which the medicine can be discharged; means for nebulizing the medicine discharged at the distal orifice; and a flow control apparatus connected to the port, said flow control apparatus comprising: a flow line communicating with the port, said flow line occupied by the medicine; a valve associated with the flow line to cause pulsed delivery of medicine through the flow line; and a draw back area associated with the flow line, said draw back area adapted to cause a reversal of flow of medicine through the flow line controller synchronized with the pulsed delivery.
Claim 5
Dependent Claim
143 words
A catheter for delivering an aerosol to a patient comprising: a shaft comprised of: an outer tubular member defining a first lumen and terminating at a distal end in a first distal orifice; an inner tubular member defining a second lumen, said inner tubular member located in the first lumen and terminating at a distal end in a second distal orifice; a manifold connected to a proximal portion of said shaft, said manifold having: a first port communicating with the first lumen for conveyance of a pressurized gas in an annular region between the inner and outer tubular members; and a second port communicating with the second lumen for conveyance of a medicine; said second distal orifice aligned with said first distal orifice to nebulize the medicine from a distal tip of the catheter; and a retractable pin located in said second lumen.
Claim 6
Dependent Claim
143 words
A catheter for delivering an aerosol to a patient comprising: a shaft comprised of: an outer tubular member defining a first lumen and terminating at a distal end in a first distal orifice; an inner tubular member defining a second lumen, said inner tubular member located in the first lumen and terminating at a distal end in a second distal orifice; a manifold connected to a proximal portion of said shaft, said manifold having: a first port communicating with the first lumen for conveyance of a pressurized gas in an annular region between the inner and outer tubular members; and a second port communicating with the second lumen for conveyance of a medicine; said second distal orifice aligned with said first distal orifice to nebulize the medicine from a distal tip of the catheter; and a retractable pin located in said second lumen.
Claim 7
Dependent Claim
143 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and a centering apparatus located on said catheter shaft close to the distal end.
Claim 8
Dependent Claim
143 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and a centering apparatus located on said catheter shaft close to the distal end.
Claim 9
Dependent Claim
33 words
The catheter system of claim 4 in which the centering apparatus has an expanded size and a reduced size and the centering device assumes the expanded size when deployed in an airway passage.
Claim 10
Dependent Claim
17 words
The catheter system of claim 4 in which the centering apparatus includes more than one expanded size.
Claim 11
Dependent Claim
21 words
The catheter system of claim 4 in which the centering apparatus has an expanded size that can be adjusted after deployment.
Claim 12
Dependent Claim
15 words
The catheter system of claim 4 in which said centering apparatus comprises gas centering jets.
Claim 13
Dependent Claim
140 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having; a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and a valve located in at least one of the lumens.
Claim 14
Dependent Claim
140 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having; a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and a valve located in at least one of the lumens.
Claim 15
Dependent Claim
19 words
The catheter system of claim 9 which the valve is located in at least one of the distal orifices.
Claim 16
Dependent Claim
20 words
The catheter system of claim 9 in which the valve is controlled from the proximal end of the nebulization catheter.
Claim 17
Dependent Claim
19 words
The catheter system of claim 9 in which the valve is actuated from the distal end of the catheter.
Claim 18
Dependent Claim
17 words
The catheter system of claim 9 in which the valve is formed by an elastically closed tip.
Claim 19
Dependent Claim
141 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and a retractable pin located in at least one of said lumens.
Claim 20
Dependent Claim
141 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and a retractable pin located in at least one of said lumens.
Claim 21
Dependent Claim
146 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending alone at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and a baffle located at the distal end of the nebulization catheter in front of the orifices.
Claim 22
Dependent Claim
146 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending alone at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and a baffle located at the distal end of the nebulization catheter in front of the orifices.
Claim 23
Dependent Claim
150 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and wherein said catheter shaft includes a third lumen extending therethrough and a fiber optic scope extending through said third lumen.
Claim 24
Dependent Claim
150 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and wherein said catheter shaft includes a third lumen extending therethrough and a fiber optic scope extending through said third lumen.
Claim 25
Dependent Claim
180 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas Pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in Proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and wherein at least a portion of said shaft surrounding said drug delivery lumen is formed of a low compliance material so that flow control at said distal drug delivery orifice of a fluid delivered through said drug delivery lumen is more responsive to flow control at a location proximal thereto.
Claim 26
Dependent Claim
180 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas Pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in Proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and wherein at least a portion of said shaft surrounding said drug delivery lumen is formed of a low compliance material so that flow control at said distal drug delivery orifice of a fluid delivered through said drug delivery lumen is more responsive to flow control at a location proximal thereto.
Claim 27
Dependent Claim
139 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and a vibrating material located close to said distal orifices.
Claim 28
Dependent Claim
139 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice; and a vibrating material located close to said distal orifices.
Claim 29
Dependent Claim
36 words
The catheter system of claim 18 in which said vibrating material is a piezoelectric material and further in which said piezoelectric material is connected to at least one electrical conductor that extends through said catheter shaft.
Claim 30
Dependent Claim
13 words
The catheter system of claim 16 which said catheter shaft comprises a bronchoscope.
Claim 31
Dependent Claim
168 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice wherein the distal gas orifice comprises a distal plug disposed at the distal end of the catheter shaft, the distal plug comprising a plurality of apertures, and wherein the apertures define gas orifices in communication with the gas lumen.
Claim 32
Dependent Claim
168 words
A catheter system for delivering an aerosol therapy to a patient comprising: a stand-alone nebulization catheter having a distal end for insertion into the patient and a proximal end, said nebulization catheter having: a catheter shaft; a gas pressurization lumen extending through said catheter shaft; a distal gas exit orifice communicating with said gas pressurization lumen, said distal gas exit orifice located at the distal end of said nebulization catheter; a drug delivery lumen extending along at least a portion of said catheter shaft; a distal drug delivery orifice communicating with said drug delivery channel, said distal drug delivery orifice located in proximity to the distal gas exit orifice so that gas exiting from said distal gas exit orifice nebulizes a drug delivered from said distal drug delivery orifice wherein the distal gas orifice comprises a distal plug disposed at the distal end of the catheter shaft, the distal plug comprising a plurality of apertures, and wherein the apertures define gas orifices in communication with the gas lumen.
Claim 33
Dependent Claim
96 words
A catheter for delivering an aerosol of medicine to a patient comprising: a liquid lumen centrally located in said shaft and adapted for conveying a medicine in liquid form; a plurality of gas lumens peripherally located around said liquid lumen and adapted for conveying a gas; a distal liquid orifice communicating with said liquid lumen; and a plurality of distal gas orifices communicating with said plurality of gas lumens, said plurality of distal gas orifices being aligned with respect to said distal liquid orifice so as to nebulize a liquid medicine discharged from the liquid orifice.
Claim 34
Dependent Claim
96 words
A catheter for delivering an aerosol of medicine to a patient comprising: a liquid lumen centrally located in said shaft and adapted for conveying a medicine in liquid form; a plurality of gas lumens peripherally located around said liquid lumen and adapted for conveying a gas; a distal liquid orifice communicating with said liquid lumen; and a plurality of distal gas orifices communicating with said plurality of gas lumens, said plurality of distal gas orifices being aligned with respect to said distal liquid orifice so as to nebulize a liquid medicine discharged from the liquid orifice.
Claim 35
Dependent Claim
52 words
The catheter of claim 22 wherein at least a portion of said shaft surrounding said liquid lumen is formed of a low compliance material so that flow control at said distal liquid orifice of a fluid delivered through said liquid lumen is more responsive to flow control at a location proximal thereto.
Claim 36
Dependent Claim
20 words
The catheter of claim 22 further comprising a tip formed by a taper in the distal end of the catheter.
Claim 37
Dependent Claim
48 words
The catheter of claim 24 , wherein the distal end of the catheter comprises a tip region that is tapered such that the lumens are in closer proximity to each other at a distal end of the tip region than at a proximal end of the tip region.
Claim 38
Dependent Claim
30 words
The catheter of claim 25 wherein a respective internal diameter of the lumens is smaller at a distal end of the tip than at a proximal end of the tip.
Claim 39
Dependent Claim
27 words
The catheter of claim 24 , wherein six said gas orifices surround said liquid orifice and six said gas lumens are congruent with the six gas orifices.
Claim 40
Dependent Claim
17 words
The catheter of claim 24 , wherein the liquid orifice has a diameter of approximately 0.002 inches.
Claim 41
Dependent Claim
19 words
The catheter of any one of claim 24 , wherein each gas orifice has a diameter of 0.002 inches.
Claim 42
Dependent Claim
30 words
The catheter of claim 22 , wherein the catheter further comprises: a proximal shaft section and a distal shaft section; and a plurality of lumens in said proximal shaft section.
Claim 43
Dependent Claim
19 words
The catheter of claim 30 wherein said liquid lumen is a central lumen and said gas lumens are non-centered.
Claim 44
Dependent Claim
114 words
The catheter of claim 31 further comprising: a distal end of the proximal shaft section connected to the proximal end of the distal shaft section; a tapered cavity formed between said distal end of said distal shaft section and said distal end of said proximal shaft section; a distal orifice located at the distal end of the distal shaft section; and a tubular extension extending the central lumen used to convey a liquid through the tapered cavity and out said distal orifice; and wherein said distal orifice is sized to permit gas flow in an annular region around the tubular extension to nebulize the liquid that exits the distal orifice of the tubular extension.
Claim 45
Dependent Claim
17 words
The catheter of claim 32 , wherein the distal orifice has an interior diameter of 0.25 inches.
Claim 46
Dependent Claim
24 words
The catheter of claim 32 , wherein the tubular extension has an outer diameter of 0.012 inches and an inner diameter of 0.007 inches.
Claim 47
Dependent Claim
15 words
The catheter of claim 30 wherein the distal shaft section is composed of stainless steel.
Claim 48
Dependent Claim
36 words
The catheter of claim 22 , comprising a tapered wire located with respect to the liquid orifice so that liquid from the liquid lumen continues to flow distally of the distal liquid orifice along the wire.
Claim 49
Dependent Claim
30 words
The catheter of claim 36 , wherein the wire has a curved shape such that gas from the gas orifices causes the wire to whip round in a spiral motion.
Claim 50
Dependent Claim
15 words
The catheter of claim 22 further comprising: a porous plug located in said liquid orifice.
Claim 51
Dependent Claim
15 words
The catheter of claim 22 further comprising: means for increasing the width of the aerosol.
Claim 52
Dependent Claim
16 words
The catheter of claim 39 , wherein the means for incasing width comprises a tapered wire.
Claim 53
Dependent Claim
18 words
The catheter of claim 22 , further comprising a peripherally located lumen which is used for sensing purposes.
Claim 54
Dependent Claim
169 words
A catheter system comprising: a catheter shaft having: a liquid lumen centrally located in said shaft and adapted for conveying a medicine in liquid form; a plurality of gas lumens peripherally located around said liquid lumen and adapted for conveying a gas; a distal liquid orifice communicating with said liquid lumen; a plurality of distal gas orifices communicating with said plurality of gas lumens, said plurality of distal gas orifices being aligned with respect to said distal liquid orifice so as to nebulize a liquid medicine discharged from the liquid orifice; wherein the catheter shaft has a proximal end and a distal end and the liquid lumen communicates at the proximal end with a port for receiving a medicine in a liquid form; and a flow control apparatus connected to the port, said flow control apparatus comprising: a flow line communicating with the port, said flow line occupied by the medicine; and a valve associated with the flow line to cause pulsed delivery of medicine through the flow line.
Claim 55
Dependent Claim
169 words
A catheter system comprising: a catheter shaft having: a liquid lumen centrally located in said shaft and adapted for conveying a medicine in liquid form; a plurality of gas lumens peripherally located around said liquid lumen and adapted for conveying a gas; a distal liquid orifice communicating with said liquid lumen; a plurality of distal gas orifices communicating with said plurality of gas lumens, said plurality of distal gas orifices being aligned with respect to said distal liquid orifice so as to nebulize a liquid medicine discharged from the liquid orifice; wherein the catheter shaft has a proximal end and a distal end and the liquid lumen communicates at the proximal end with a port for receiving a medicine in a liquid form; and a flow control apparatus connected to the port, said flow control apparatus comprising: a flow line communicating with the port, said flow line occupied by the medicine; and a valve associated with the flow line to cause pulsed delivery of medicine through the flow line.
Claim 56
Dependent Claim
18 words
The catheter of claim 22 further comprising a safety stop on a proximal portion of the catheter shaft.
Claim 57
Dependent Claim
13 words
The catheter of claim 22 further comprising: graduated markings on said catheter shaft.
Claim 58
Dependent Claim
22 words
The catheter of claim 22 further comprising: luer lock connectors on proximal ports communicating with said gas lumens and said liquid lumen.
Claim 59
Dependent Claim
13 words
The catheter of claim 22 further comprising: a stripe on said catheter shaft.
Claim 60
Dependent Claim
26 words
The catheter of claim 22 , wherein said catheter shaft comprises: a further lumen extending therethrough; and a fiber optic scope extending through said further lumen.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2007-05-04 | 2007-11-03 | 2008-05-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2011-05-04 | 2011-11-03 | 2012-05-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2015-05-04 | 2015-11-03 | 2016-05-04 | $7700.00 | Window Closed / Lapsed |