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EP0289336A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Aerosolization of protein therapeutic agent

Assignee: Cooper Laboratories Inc
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Filing: 1988-04-29
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Granted: —
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Expires: 2008-04-29
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Abstract

Abstract Aerosolization of therapeutic proteins is demonstrated using recombinant α₁-antitrypsin for treatment of emphysema as paradigmatic.

Inventors

  • 👤 Nicolaas J. Roosdorp
  • 👤 Ronald G. Crystal

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 14:46
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/007; A61K9/0073; A61K9/0078; A61K38/00; A61K38/16; A61K38/55; A61K38/57

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 22 words
An aerosol formulation comprising from about 0.1 to 15% of a peptide agent used for prophylactic or therapeutic treatment of the lungs.
Claim 2
Dependent Claim 22 words
An aerosol formulation comprising from about 0.1 to 15% of a peptide agent used for prophylactic or therapeutic treatment of the lungs.
Claim 3
Dependent Claim 21 words
An aerosol formulation according to claim 1, wherein said peptide agent is present in from about 0.5 to 10 weight percent.
Claim 4
Dependent Claim 17 words
An aerosol formulation according to any of claims 1 or 2, wherein said peptide agent is α₁-trypsin.
Claim 5
Dependent Claim 20 words
An aerosol formulation according to any one of the preceding claims, wherein said peptide is of at least 30 kD.
Claim 6
Dependent Claim 20 words
An aerosol formulation according to any one of the preceding claims, wherein said peptide agent is produced by recombinant techniques.
Claim 7
Dependent Claim 15 words
An aerosol formulation according to claim 5, wherein said peptide agent is produced in yeast.

References Cited (Backward Citations)

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