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US6254632B1 Expired / Lapsed US ⏱️ 0.0 years remaining

Implantable medical device having protruding surface structures for drug delivery and cover attachment

Assignee: Abbott Cardiovascular Systems Inc
•
Filing: 2000-09-28
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Granted: 2001-07-03
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Expires: 2020-09-28
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Abstract

Abstract A method for forming an implantable medical device, such as a stent, covered stent, or synthetic stent graft, is provided. Protruding structures are formed on a surface of the device. The protruding structures have a central depression region surrounded by a lip. The protruding structures can have a variety of shapes, including circular and ovular shapes, or the protruding structure can form a groove. The protruding structures can be used to engage a cover. Glue can be added to the protruding structures to help secure the cover. The protruding structures can also contain a therapeutic substance or substances for release in situ. The protruding structures can be formed using a laser discharge to create a hole in the stent surface followed by directing a pressurized stream of grit at the surface.

Inventors

  • 👤 Steven Z. Wu
  • 👤 Sameer Harish
  • 👤 Deborra Sanders-Millare
  • 👤 Judy A. Guruwaiya

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 03:54
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/86; A61F2/90; A61F2/91; A61F2/915; A61F2/02; A61F2/04; A61F2/06; A61F2/07; A61F2002/075; A61F2002/91516; A61F2002/91533; A61F2220/00; A61F2220/0025; A61F2220/005; A61F2230/00; A61F2230/0002; A61F2230/0004; A61F2230/0013; A61F2230/0028; A61F2230/0054; A61F2250/00; A61F2250/0058; A61F2250/0067; A61F2250/0068

Claims Analysis

Total Claims: 33
Claim 1
Independent Claim 71 words
An implantable medical device comprising: a substrate having a first surface, said first surface having a plurality of protruding structures, wherein each of said protruding structures includes a depression region having a bottom surface, said depression region approximately centrally located in said protruding structure; and a lip surrounding at least a portion of said depression region, said lip having a height that extends above said bottom surface and said first surface.
Claim 2
Dependent Claim 71 words
An implantable medical device comprising: a substrate having a first surface, said first surface having a plurality of protruding structures, wherein each of said protruding structures includes a depression region having a bottom surface, said depression region approximately centrally located in said protruding structure; and a lip surrounding at least a portion of said depression region, said lip having a height that extends above said bottom surface and said first surface.
Claim 3
Dependent Claim 17 words
The implantable medical device of claim 1 , wherein said depression region and lip are substantially circular.
Claim 4
Dependent Claim 16 words
The implantable medical device claim 1 , wherein said depression region and lip form a groove.
Claim 5
Dependent Claim 55 words
The implantable medical device of claim 1 , wherein said substrate has a thickness defined by a distance between said first surface and an opposite second surface, said protruding structure has a depth defined by a distance between said bottom surface and said first surface, and said depth is less than 80% of said thickness.
Claim 6
Dependent Claim 17 words
The implantable medical device of claim 1 , wherein said bottom surface is above said first surface.
Claim 7
Dependent Claim 17 words
The implantable medical device of claim 1 , wherein said bottom surface is beneath said first surface.
Claim 8
Dependent Claim 22 words
The implantable medical device of claim 1 further comprising: a cover overlying said first surface, wherein said protruding structures engage said cover.
Claim 9
Dependent Claim 23 words
The implantable medical device of claim 7 further comprising glue located in said depression region of at least some of said protruding structures.
Claim 10
Dependent Claim 15 words
The implantable medical device of claim 7 , wherein said cover comprises a therapeutic substance.
Claim 11
Dependent Claim 16 words
The stent of claim 1 , wherein said depression region contains one or more therapeutic substances.
Claim 12
Dependent Claim 19 words
The stent of claim 10 , wherein said one or more therapeutic substances is covered by a polymeric layer.
Claim 13
Dependent Claim 73 words
A stent comprising: a body having a generally cylindrical shape and an outer surface, wherein said outer surface includes a plurality of protruding structures, wherein said protruding structures include: a depression region having a bottom surface, said depression region approximately centrally located in said protruding structure; and a lip surrounding at least a portion of said depression region, said lip having a height that extends above said bottom surface and said outer surface.
Claim 14
Dependent Claim 73 words
A stent comprising: a body having a generally cylindrical shape and an outer surface, wherein said outer surface includes a plurality of protruding structures, wherein said protruding structures include: a depression region having a bottom surface, said depression region approximately centrally located in said protruding structure; and a lip surrounding at least a portion of said depression region, said lip having a height that extends above said bottom surface and said outer surface.
Claim 15
Dependent Claim 20 words
The stent of claim 12 further comprising: a cover overlying said outer surface, wherein said protruding structures engage said cover.
Claim 16
Dependent Claim 56 words
The stent of claim 13 , wherein said cover has a first end and an opposing second end, wherein said stent comprises a first section and a second section, and wherein said first section is attached to said first end of said cover and said second section is attached to said second end of said cover.
Claim 17
Dependent Claim 22 words
The stent of claim 13 , further comprising glue located in said depression region of at least some of said protruding structures.
Claim 18
Dependent Claim 13 words
The stent of claim 13 , wherein said cover comprises a therapeutic substance.
Claim 19
Dependent Claim 16 words
The stent of claim 12 , wherein said depression region and said lip are substantially circular.
Claim 20
Dependent Claim 16 words
The stent of claim 17 , wherein said depression region contains one or more therapeutic substances.
Claim 21
Dependent Claim 19 words
The stent of claim 18 , wherein said one or more therapeutic substances is covered by a polymeric layer.
Claim 22
Dependent Claim 16 words
The stent of claim 12 , wherein said depression region and said lip form a groove.
Claim 23
Dependent Claim 15 words
The stent of claim 20 , wherein said groove contains one or more therapeutic substances.
Claim 24
Dependent Claim 19 words
The stent of claim 21 , wherein said one or more therapeutic substances is covered by a polymeric layer.
Claim 25
Dependent Claim 53 words
The stent of claim 12 , wherein said body has a thickness defined by a distance between said outer surface and an opposite inner surface, said protruding structure has a depth defined by a distance between said bottom surface and said outer surface, and said depth is less than 80% of said thickness.
Claim 26
Dependent Claim 15 words
The stent of claim 12 , wherein said bottom surface is above said outer surface.
Claim 27
Dependent Claim 16 words
The stent of claim 24 , wherein said depression region contains one or more therapeutic substances.
Claim 28
Dependent Claim 19 words
The stent of claim 25 , wherein said one or more therapeutic substances is covered by a polymeric layer.
Claim 29
Dependent Claim 15 words
The stent of claim 12 , wherein said bottom surface is beneath said outer surface.
Claim 30
Dependent Claim 16 words
The stent of claim 27 , wherein said depression region contains one or more therapeutic substances.
Claim 31
Dependent Claim 19 words
The stent of claim 28 , wherein said one or more therapeutic substances is covered by a polymeric layer.
Claim 32
Dependent Claim 16 words
The stent of claim 12 , wherein said depression region contains one or more therapeutic substances.
Claim 33
Dependent Claim 19 words
The stent of claim 30 , wherein said one or more therapeutic substances is covered by a polymeric layer.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2004-07-02 2005-01-01 2005-07-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2008-07-02 2009-01-01 2009-07-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2012-07-02 2013-01-01 2013-07-03 $7700.00 Window Closed / Lapsed

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