US6074673A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Slow-release, self-absorbing, drug delivery system
Assignee: Individual
•
Filing: 1996-04-22
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Granted: 2000-06-13
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Expires: 2016-04-22
Abstract
Abstract The present invention is directed to an implantable, slow-release, self-absorbing, biologically compatible drug delivery system such as slow-release pharmaceutical compositions, including for example, slow-release, allergy desensitization compositions containing one or more allergens in combination with a biologically-compatible, self-absorbing matrix. The present system is useful for treating disorders including, for example, infections, deficiencies or allergies. The present invention is also directed to methods of treating a patient suffering from a disorder, as well as methods for desensitizing a patient to one or more allergens. The present invention also relates to a device for implanting the present composition in a patient.
Inventors
- 👤 Manuel Guillen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:28
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; A61K39/00; A61K39/35; Y; Y10; Y10T; Y10T428/00; Y10T428/29; Y10T428/2982; Y10T428/2984; Y10T428/2985
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
72 words
A slow-release, self-absorbing pharmaceutical composition comprising one or more active agents in combination with a biologically-compatible, self-absorbing matrix material, said one or more active agents mixed homogeneously with said biologically-compatible, self-absorbing matrix material to form a biologically-compatible, self-absorbing dry solid matrix, said matrix being shaped to be one selected from the group consisting of a solid cylinder and a hollow sleeve, and otherwise suitably configured for subcutaneously implanting with an injecting device.
Claim 2
Dependent Claim
72 words
A slow-release, self-absorbing pharmaceutical composition comprising one or more active agents in combination with a biologically-compatible, self-absorbing matrix material, said one or more active agents mixed homogeneously with said biologically-compatible, self-absorbing matrix material to form a biologically-compatible, self-absorbing dry solid matrix, said matrix being shaped to be one selected from the group consisting of a solid cylinder and a hollow sleeve, and otherwise suitably configured for subcutaneously implanting with an injecting device.
Claim 3
Dependent Claim
73 words
A slow-release, self-absorbing allergy desensitization composition comprising one or more allergens in combination with a biologically-compatible, self-absorbing matrix material, said one or more active agents mixed homogeneously with said biologically-compatible, self-absorbing matrix material to form a biologically-compatible, self-absorbing dry solid matrix, said matrix being shaped to be one selected from the group consisting of a solid cylinder and a hollow sleeve, and otherwise being suitably configured for subcutaneous implanting with an infecting device.
Claim 4
Dependent Claim
73 words
A slow-release, self-absorbing allergy desensitization composition comprising one or more allergens in combination with a biologically-compatible, self-absorbing matrix material, said one or more active agents mixed homogeneously with said biologically-compatible, self-absorbing matrix material to form a biologically-compatible, self-absorbing dry solid matrix, said matrix being shaped to be one selected from the group consisting of a solid cylinder and a hollow sleeve, and otherwise being suitably configured for subcutaneous implanting with an infecting device.
Claim 5
Dependent Claim
20 words
The slow-release, self-absorbing pharmaceutical composition of claim 1, wherein said biologically-compatible, self-absorbing matrix comprises one or more self-absorbing biologically-compatible materials.
Claim 6
Dependent Claim
29 words
The slow-release, self-absorbing pharmaceutical composition of claim 3, wherein said one or more self-absorbing, biologically-compatible materials are selected from the group consisting of: polydioxanone, polyglycolic acid and polyglactic acid.
Claim 7
Dependent Claim
21 words
The slow-release, self-absorbing allergy desensitization composition of claim 2, wherein said biologically-compatible, self-absorbing matrix comprises one or more self-absorbing biologically-compatible materials.
Claim 8
Dependent Claim
30 words
The slow-release, self-absorbing allergy desensitization composition of claim 5, wherein said one or more self-absorbing, biologically-compatible, materials are selected from the group consisting of: polydioxanone, polyglycolic acid and polyglactic acid.
Claim 9
Dependent Claim
22 words
The allergy-desensitization kit of any one of claims 3 or 4, wherein said biologically-compatible matrix comprises one or more self-absorbing, biologically-compatible materials.
Claim 10
Dependent Claim
27 words
The allergy-desensitization kit of claim 7, wherein said one or more self-absorbing, biologically-compatible materials are selected from the group consisting of: polydioxanone, polyglycolic acid and polyglactic acid.
Claim 11
Dependent Claim
15 words
The pharmaceutical composition of claim 1, wherein said pharmaceutical composition comprises a single dosage unit.
Claim 12
Dependent Claim
15 words
The pharmaceutical composition of claim 1, wherein said pharmaceutical composition comprises a multiple dosage unit.
Claim 13
Dependent Claim
15 words
The pharmaceutical composition of claim 9, wherein said pharmaceutical composition comprises a single dosage unit.
Claim 14
Dependent Claim
15 words
The pharmaceutical composition of claim 10, wherein said pharmaceutical composition comprises a single dosage unit.
References Cited (Backward Citations)
US2683136A
Cited
US3297033A
Cited
US3442871A
Cited
US3468853A
Cited
US3457280A
Cited
US3435008A
Cited
US3597450A
Cited
US4122129A
Cited
US5019094A
Cited
US5403347A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-06-13 | 2003-12-13 | 2004-06-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-06-13 | 2007-12-13 | 2008-06-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-06-13 | 2011-12-13 | 2012-06-13 | $7700.00 | Window Closed / Lapsed |