US6074338A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Medical appliances for the treatment of blood vessels by means of ionizing radiation
Assignee: Schneider Europe GmbH
•
Filing: 1994-06-28
•
Granted: 2000-06-13
•
Expires: 2014-06-28
Abstract
Abstract A catheter with a balloon mounted coaxially thereon, and a radiation emitting source disposed and essentially centered in the catheter distal portion.
Inventors
- 👤 Youri Popowski
- 👤 Vitali Verin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:49
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1002; A61M; A61M25/00; A61M25/10; A61M2025/1043; A61M2025/1047; A61N2005/1003
Claims Analysis
Total Claims: 53
Claim 1
Independent Claim
77 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a beta radiation emitting source comprising 90 Yttrium disposed within the catheter distal portion; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the beta radiation emitting source in the coronary blood vessel.
Claim 2
Dependent Claim
77 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a beta radiation emitting source comprising 90 Yttrium disposed within the catheter distal portion; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the beta radiation emitting source in the coronary blood vessel.
Claim 3
Dependent Claim
15 words
The medical device of claim 1, wherein the beta radiation emitting source comprises a filament.
Claim 4
Dependent Claim
18 words
The medical device of claim 2, wherein the filament diameter is less than or equal to 0.9 mm.
Claim 5
Dependent Claim
15 words
The medical device of claim 3, wherein the filament diameter is less than 0.2 mm.
Claim 6
Dependent Claim
15 words
The medical device of claim 2, wherein the filament is axially moveable within the catheter.
Claim 7
Dependent Claim
19 words
The medical device of claim 5, wherein the filament is adapted for insertion into and withdrawal from the catheter.
Claim 8
Dependent Claim
24 words
The medical device of claim 2, further comprising a guide wire slidably disposed within the catheter, wherein the filament is affixed to the guidewire.
Claim 9
Dependent Claim
15 words
The medical device of claim 2, wherein the filament is affixed to a titanium wire.
Claim 10
Dependent Claim
19 words
The medical device of claim 1, wherein the beta radiation emitting source is essentially axially centered within the balloon.
Claim 11
Dependent Claim
20 words
The medical device of claim 1, wherein the balloon is substantially cylindrical upon expansion and annularly affixed to the catheter.
Claim 12
Dependent Claim
18 words
The medical device of claim 10, wherein the balloon is adapted to perform a percutaneous transluminal angioplasty procedure.
Claim 13
Dependent Claim
94 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a radiation emitting source disposed within the catheter distal portion, the radiation emitting source comprising 90 Yttrium adapted to irradiate a blood vessel wall without substantially irradiating tissue beyond the blood vessel wall; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially center the radiation emitting source in the coronary blood vessel.
Claim 14
Dependent Claim
94 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a radiation emitting source disposed within the catheter distal portion, the radiation emitting source comprising 90 Yttrium adapted to irradiate a blood vessel wall without substantially irradiating tissue beyond the blood vessel wall; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially center the radiation emitting source in the coronary blood vessel.
Claim 15
Dependent Claim
14 words
The medical device of claim 12, wherein the radiation emitting source comprises a filament.
Claim 16
Dependent Claim
18 words
The medical device of claim 13, wherein the filament diameter is less than or equal to 0.9 mm.
Claim 17
Dependent Claim
15 words
The medical device of claim 14, wherein the filament diameter is less than 0.2 mm.
Claim 18
Dependent Claim
24 words
The medical device of claim 13, further comprising a guide wire slidably disposed within the catheter, wherein the filament is affixed to the guidewire.
Claim 19
Dependent Claim
15 words
The medical device of claim 13, wherein the filament is affixed to a titanium wire.
Claim 20
Dependent Claim
18 words
The medical device of claim 12, wherein the radiation emitting source is essentially axially centered within the balloon.
Claim 21
Dependent Claim
15 words
The medical device of claim 13, wherein the filament is axially moveable within the catheter.
Claim 22
Dependent Claim
19 words
The medical device of claim 19, wherein the filament is adapted for insertion into and withdrawal from the catheter.
Claim 23
Dependent Claim
20 words
The medical device of claim 12, wherein the balloon is substantially cylindrical upon expansion and annularly affixed to the catheter.
Claim 24
Dependent Claim
18 words
The medical device of claim 21, wherein the balloon is adapted to perform a percutaneous transluminal angioplasty procedure.
Claim 25
Dependent Claim
18 words
The medical device of claim 12, wherein the radiation emitting filament is essentially axially centered within the balloon.
Claim 26
Dependent Claim
83 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a radiation emitting filament comprising 90 Yttrium disposed within the catheter distal portion and having a diameter less than 0.2 mm; and (c) a balloon surrounding at least part of the catheter distal portion, and adapted to radially expand and essentially radially center the radiation emitting filament in the coronary blood vessel.
Claim 27
Dependent Claim
83 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) a radiation emitting filament comprising 90 Yttrium disposed within the catheter distal portion and having a diameter less than 0.2 mm; and (c) a balloon surrounding at least part of the catheter distal portion, and adapted to radially expand and essentially radially center the radiation emitting filament in the coronary blood vessel.
Claim 28
Dependent Claim
15 words
The medical device of claim 24, wherein the filament is axially moveable within the catheter.
Claim 29
Dependent Claim
19 words
The medical device of claim 25, wherein the filament is adapted for insertion into and withdrawal from the catheter.
Claim 30
Dependent Claim
24 words
The medical device of claim 24, further comprising a guide wire slidably disposed within the catheter, wherein the filament is affixed to the guidewire.
Claim 31
Dependent Claim
15 words
The medical device of claim 24, wherein the filament is affixed to a titanium wire.
Claim 32
Dependent Claim
20 words
The medical device of claim 24, wherein the balloon is substantially cylindrical upon expansion and annularly affixed to the catheter.
Claim 33
Dependent Claim
18 words
The medical device of claim 29, wherein the balloon is adapted to perform a percutaneous transluminal angioplasty procedure.
Claim 34
Dependent Claim
69 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) 90 Yttrium disposed within the catheter distal portion; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the 90 Yttrium in the coronary blood vessel.
Claim 35
Dependent Claim
69 words
A medical device comprising: (a) a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; (b) 90 Yttrium disposed within the catheter distal portion; and (c) a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the 90 Yttrium in the coronary blood vessel.
Claim 36
Dependent Claim
16 words
The medical device of claim 31, where in the 90 Yttrium is comprised in a filament.
Claim 37
Dependent Claim
15 words
The medical device of claim 32, wherein the filament is axially moveable within the catheter.
Claim 38
Dependent Claim
19 words
The medical device of claim 33, wherein the filament is adapted for insertion into and withdrawal from the catheter.
Claim 39
Dependent Claim
18 words
The medical device of claim 32, wherein the filament diameter is less than or equal to 0.9 mm.
Claim 40
Dependent Claim
15 words
The medical device of claim 35, wherein the filament diameter is less than 0.2 mm.
Claim 41
Dependent Claim
24 words
The medical device of claim 32, further comprising a guide wire slidably disposed within the catheter, wherein the filament is affixed to the guidewire.
Claim 42
Dependent Claim
15 words
The medical device of claim 32, wherein the filament is affixed to a titanium wire.
Claim 43
Dependent Claim
17 words
The medical device of claim 31, wherein the 90 Yttrium is essentially axially centered within the balloon.
Claim 44
Dependent Claim
20 words
The medical device of claim 31, wherein the balloon is substantially cylindrical upon expansion and annularly affixed to the catheter.
Claim 45
Dependent Claim
18 words
The medical device of claim 40, wherein the balloon is adapted to perform a percutaneous transluminal angioplasty procedure.
Claim 46
Independent Claim
125 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a beta radiation emitting source comprising 90 Yttrium disposed within the catheter distal portion; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the beta radiation emitting source in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the beta radiation emitting source essentially radially centered within a blood vessel; and (c) irradiating the treatment site with radiation including beta radiation and devoid of gamma radiation.
Claim 47
Independent Claim
125 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a beta radiation emitting source comprising 90 Yttrium disposed within the catheter distal portion; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the beta radiation emitting source in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the beta radiation emitting source essentially radially centered within a blood vessel; and (c) irradiating the treatment site with radiation including beta radiation and devoid of gamma radiation.
Claim 48
Independent Claim
146 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a radiation emitting source disposed within the catheter distal portion, the radiation emitting source comprising 90 Yttrium adapted to irradiate a blood vessel wall without substantially irradiating tissue beyond the blood vessel wall; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially center the radiation emitting source in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the radiation emitting source essentially radially centered within a blood vessel formed of a blood vessel wall; and (c) irradiating the blood wall without substantially irradiating tissue beyond the blood vessel wall.
Claim 49
Independent Claim
146 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a radiation emitting source disposed within the catheter distal portion, the radiation emitting source comprising 90 Yttrium adapted to irradiate a blood vessel wall without substantially irradiating tissue beyond the blood vessel wall; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially center the radiation emitting source in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the radiation emitting source essentially radially centered within a blood vessel formed of a blood vessel wall; and (c) irradiating the blood wall without substantially irradiating tissue beyond the blood vessel wall.
Claim 50
Independent Claim
120 words
A method of preventing restenosis in a blood vassal comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a radiation emitting filament comprising 90 Yttrium disposed within the catheter distal portion and having a diameter less than 0.2 mm; and a balloon surrounding at least part of the catheter distal portion, and adapted to radially expand and essentially radially center the radiation emitting filament in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the radiation emitting filament essentially radially centered within a blood vessel; and (c) irradiating the treatment site.
Claim 51
Independent Claim
120 words
A method of preventing restenosis in a blood vassal comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; a radiation emitting filament comprising 90 Yttrium disposed within the catheter distal portion and having a diameter less than 0.2 mm; and a balloon surrounding at least part of the catheter distal portion, and adapted to radially expand and essentially radially center the radiation emitting filament in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the radiation emitting filament essentially radially centered within a blood vessel; and (c) irradiating the treatment site.
Claim 52
Independent Claim
105 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; 90 Yttrium disposed within the catheter distal portion; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the 90 Yttrium in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the 90 Yttrium essentially radially centered within a blood vessel; and (c) irradiating the treatment site.
Claim 53
Independent Claim
105 words
A method of preventing restenosis in a blood vessel comprising: (a) providing a medical device comprising a flexible catheter having a proximal portion and a distal portion, the distal portion sized and configured for intraluminal placement in a coronary blood vessel; 90 Yttrium disposed within the catheter distal portion; and a balloon surrounding at least part of the catheter distal portion and adapted to radially expand and essentially radially center the 90 Yttrium in the coronary blood vessel; (b) disposing the catheter distal portion at a treatment site with the 90 Yttrium essentially radially centered within a blood vessel; and (c) irradiating the treatment site.
References Cited (Backward Citations)
US1442051A
Cited
US2546761A
Cited
US2862108A
Cited
DE1065989B
Cited
US2955208A
Cited
US3060924A
Cited
US3147383A
Cited
US3324847A
Cited
US3505991A
Cited
US3674006A
Cited
US3643096A
Cited
US3861380A
Cited
US3669093A
Cited
US3750653A
Cited
US3866050A
Cited
US3811426A
Cited
US3927325A
Cited
US3970073A
Cited
US4096862A
Cited
US4220864A
Cited
US4588395A
Cited
US4225790A
Cited
US4281252A
Cited
US4244357A
Cited
US4314157A
Cited
US4364376A
Cited
US4578061A
Cited
US4402308A
Cited
US4610662A
Cited
US4631415A
Cited
US4842590A
Cited
US4584991A
Cited
US4763671A
Cited
US4960411A
Cited
US4815449A
Cited
US4697575A
Cited
US4897076A
Cited
US4702228A
Cited
US4784116A
Cited
US5242394A
Cited
US5141487A
Cited
US4706652A
Cited
US4763642A
Cited
US5030194A
Cited
US4881937A
Cited
US5084001A
Cited
US4819618A
Cited
US4976266A
Cited
US4782834A
Cited
US4851694A
Cited
US4770653A
Cited
US5106360A
Cited
US4940452A
Cited
US4936823A
Cited
US5649924A
Cited
US4891165A
Cited
US4994013A
Cited
US5163896A
Cited
US5575749A
Cited
US5084002A
Cited
US4976680A
Cited
US5183455A
Cited
US5103395A
Cited
US4969863A
Cited
US4861520A
Cited
US4983167A
Cited
US5203772A
Cited
US5012357A
Cited
US4963128A
Cited
US5032113A
Cited
US5147282A
Cited
US5111829A
Cited
US4976690A
Cited
US5176617A
Cited
US5059166A
Cited
US5199939A
Cited
US5199939B1
Cited
US5267960A
Cited
US5213561A
Cited
US5120973A
Cited
US5139473A
Cited
US5092834A
Cited
US5624372A
Cited
US5282781A
Cited
US5807231A
Cited
US5385152A
Cited
US5354257A
Cited
US5484384A
Cited
US5395300A
Cited
US5429582A
Cited
US5611767A
Cited
US5370685A
Cited
US5344383A
Cited
US5411466A
Cited
US5302168A
Cited
US5295995A
Cited
US5391139A
Cited
US5425720A
Cited
US5308356A
Cited
US5405309A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-06-13 | 2003-12-13 | 2004-06-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-06-13 | 2007-12-13 | 2008-06-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-06-13 | 2011-12-13 | 2012-06-13 | $7700.00 | Window Closed / Lapsed |