US5213561A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and devices for preventing restenosis after angioplasty
Assignee: MARTIN H FRANK JR
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Filing: 1992-03-19
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Granted: 1993-05-25
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Expires: 2012-03-19
Abstract
Abstract The incidence of restenosis after angioplasty is reduced by exposing the potentially stenotic site to radiation from a source within the same vascular structure in which the site is located. The radioactive source can be mounted at the distal end of a guidewire, or in a balloon catheter, or on a balloon expansible stent, and is inserted through the vascular structure to the site to be exposed.
Inventors
- 👤 Joseph S. Weinstein
- 👤 H. Frank Martin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:24
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1002; A61B; A61B17/00; A61B17/22; A61B2017/22051; A61B2017/22065; A61B2017/22068; A61M; A61M25/00; A61M25/10; A61M2025/1043; A61M2025/1047; A61M25/104; A61N2005/1004
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
150 words
A device for reducing the incidence of restenosis at a site within a vascular structure following percutaneous transluminal coronary or peripheral angioplasty of said site, comprising, an elongated flexible member which is insertable longitudinally through vascular structure, an intravascular radioactive source mounted at a distal end of said flexible member, said source being positionable at an intravascular angioplasty site within said vascular structure for radiating said site by inserting said flexible member longitudinally through said structure, radiation shielding means on said flexible member for selectively shielding and exposing said radioactive source, said shielding means being a retractable sleeve around said radioactive source, said sleeve being selectively movable relative to said source to expose said source when said source has been positioned at said site, thereby to radiate said site, said flexible member, source and shielding means having dimensions sufficiently small that said device is insertable longitudinally through said vascular structure.
Claim 2
Independent Claim
150 words
A device for reducing the incidence of restenosis at a site within a vascular structure following percutaneous transluminal coronary or peripheral angioplasty of said site, comprising, an elongated flexible member which is insertable longitudinally through vascular structure, an intravascular radioactive source mounted at a distal end of said flexible member, said source being positionable at an intravascular angioplasty site within said vascular structure for radiating said site by inserting said flexible member longitudinally through said structure, radiation shielding means on said flexible member for selectively shielding and exposing said radioactive source, said shielding means being a retractable sleeve around said radioactive source, said sleeve being selectively movable relative to said source to expose said source when said source has been positioned at said site, thereby to radiate said site, said flexible member, source and shielding means having dimensions sufficiently small that said device is insertable longitudinally through said vascular structure.
Claim 3
Dependent Claim
31 words
The device of claim 1 wherein said flexible member is a guidewire, said sleeve and radioactive source being mounted on and movable with said guidewire for withdrawal from said vascular structure.
Claim 4
Dependent Claim
12 words
The device of claim 1 wherein said flexible member is a guidewire.
Claim 5
Dependent Claim
16 words
The device of claim 3 wherein said guidewire comprises an outer sleeve around an inner wire.
Claim 6
Dependent Claim
19 words
The device of claim 4 wherein said radioactive source is mounted to a distal end of said inner wire.
Claim 7
Dependent Claim
12 words
The device of claim 1 wherein said radioactive source is Cobalt 60.
Claim 8
Independent Claim
144 words
A device for reducing the incidence of restenosis at a site within a vascular structure following percutaneous transluminal coronary or peripheral angioplasty of said site, comprising, an elongated flexible member which is insertable longitudinally through vascular structure, an intravascular radioactive source mounted at a distal end of said flexible member, said source being positionable at an intravascular angioplasty site within said vascular structure for radiating said site by inserting said flexible member longitudinally through said structure, radiation shielding means on said flexible member for selectively shielding and exposing said radioactive source, said shielding means being a retractable sleeve around said radioactive source, said sleeve being in the form of a coil having a radiation shielding coating, said sleeve being selectively axially shiftable relative to said source to expose said source when said source has been positioned at said site, thereby to radiate said site.
Claim 9
Independent Claim
144 words
A device for reducing the incidence of restenosis at a site within a vascular structure following percutaneous transluminal coronary or peripheral angioplasty of said site, comprising, an elongated flexible member which is insertable longitudinally through vascular structure, an intravascular radioactive source mounted at a distal end of said flexible member, said source being positionable at an intravascular angioplasty site within said vascular structure for radiating said site by inserting said flexible member longitudinally through said structure, radiation shielding means on said flexible member for selectively shielding and exposing said radioactive source, said shielding means being a retractable sleeve around said radioactive source, said sleeve being in the form of a coil having a radiation shielding coating, said sleeve being selectively axially shiftable relative to said source to expose said source when said source has been positioned at said site, thereby to radiate said site.
Claim 10
Dependent Claim
16 words
The device of claim 7 wherein said coating is a lead coating on a wire coil.
Claim 11
Independent Claim
141 words
A device for reducing the incidence of restenosis at a site within a vascular structure following percutaneous transluminal coronary of peripheral angioplasty of said site, comprising, an elongated flexible member which is insertable longitudinally through vascular structure, an intravascular radioactive source mounted at a distal end of said flexible member, said source being positionable at an intravascular angioplasty site within said vascular structure for radiating said site by inserting said flexible member longitudinally through said structure, radiation shielding means on said flexible member for selectively shielding and exposing said radioactive source, said shielding means being a retractable sleeve around said radioactive source, said sleeve being selectively movable relative to said source to expose said source when said source has been positioned at said site, thereby to radiate said site, said flexible member being guidewire which extends axially through a balloon catheter.
Claim 12
Independent Claim
141 words
A device for reducing the incidence of restenosis at a site within a vascular structure following percutaneous transluminal coronary of peripheral angioplasty of said site, comprising, an elongated flexible member which is insertable longitudinally through vascular structure, an intravascular radioactive source mounted at a distal end of said flexible member, said source being positionable at an intravascular angioplasty site within said vascular structure for radiating said site by inserting said flexible member longitudinally through said structure, radiation shielding means on said flexible member for selectively shielding and exposing said radioactive source, said shielding means being a retractable sleeve around said radioactive source, said sleeve being selectively movable relative to said source to expose said source when said source has been positioned at said site, thereby to radiate said site, said flexible member being guidewire which extends axially through a balloon catheter.
Claim 13
Independent Claim
150 words
A device for reducing the incidence of restenosis at a site within a vascular structure following percutaneous transluminal coronary or peripheral angioplasty of said site, comprising, an elongated flexible member which is insertable longitudinally through vascular structure, an intravascular radioactive source mounted at a distal end of said flexible member, said source being positionable at an intravascular angioplasty site within said vascular structure for radiating said site by inserting said flexible member longitudinally through said structure, radiation shielding means on said flexible member for selectively shielding and exposing said radioactive source, said shielding means being a retractable sleeve around said radioactive source, said sleeve being selectively movable relative to said source to expose said source when said source has been positioned at said site, thereby to radiate said site, said flexible member being a guidewire which comprises an outer sleeve around an inner wire, said sleeve comprising a wire coil.
Claim 14
Independent Claim
150 words
A device for reducing the incidence of restenosis at a site within a vascular structure following percutaneous transluminal coronary or peripheral angioplasty of said site, comprising, an elongated flexible member which is insertable longitudinally through vascular structure, an intravascular radioactive source mounted at a distal end of said flexible member, said source being positionable at an intravascular angioplasty site within said vascular structure for radiating said site by inserting said flexible member longitudinally through said structure, radiation shielding means on said flexible member for selectively shielding and exposing said radioactive source, said shielding means being a retractable sleeve around said radioactive source, said sleeve being selectively movable relative to said source to expose said source when said source has been positioned at said site, thereby to radiate said site, said flexible member being a guidewire which comprises an outer sleeve around an inner wire, said sleeve comprising a wire coil.
Claim 15
Independent Claim
161 words
A device for reducing the incidence of restenosis at a site within a vascular structure following percutaneous transluminal coronary or peripheral angioplasty of said site, comprising, an elongated flexible member which is insertable longitudinally through vascular structure, said flexible member being a plastic tube of a catheter having a balloon at one end thereof, an intravascular radioactive source mounted at a distal end of said flexible member, said source being positionable at an intravascular angioplasty site within said vascular structure for radiating said site by inserting said flexible member longitudinally through said structure, said radioactive source being mounted to the distal end of said tube, inside said balloon. radiation shielding means on said flexible member for selectively shielding and exposing said radioactive source, said shielding means being a retractable sleeve around said radioactive source, said sleeve being selectively movable relative to said source to expose said source when said source has been positioned at said site, thereby to radiate said site.
Claim 16
Independent Claim
161 words
A device for reducing the incidence of restenosis at a site within a vascular structure following percutaneous transluminal coronary or peripheral angioplasty of said site, comprising, an elongated flexible member which is insertable longitudinally through vascular structure, said flexible member being a plastic tube of a catheter having a balloon at one end thereof, an intravascular radioactive source mounted at a distal end of said flexible member, said source being positionable at an intravascular angioplasty site within said vascular structure for radiating said site by inserting said flexible member longitudinally through said structure, said radioactive source being mounted to the distal end of said tube, inside said balloon. radiation shielding means on said flexible member for selectively shielding and exposing said radioactive source, said shielding means being a retractable sleeve around said radioactive source, said sleeve being selectively movable relative to said source to expose said source when said source has been positioned at said site, thereby to radiate said site.
Claim 17
Dependent Claim
23 words
The device of claim 1 further including a shiftable sleeve around said tube, said sleeve having a shield for selectively exposing said source.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-05-24 | 1996-11-23 | 1997-05-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-05-24 | 2000-11-23 | 2001-05-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-05-24 | 2004-11-23 | 2005-05-25 | $7700.00 | Window Closed / Lapsed |