Patent US3838379A successfully refreshed from Google Patents.
US6045495A
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Apparatus and method to treat a disease process in a luminal structure
Assignee: Columbia University
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Filing: 1996-07-25
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Granted: 2000-04-04
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Expires: 2016-07-25
Abstract
Abstract An apparatus and a method to treat a disease process in a luminal structure. A guidewire is inserted into the patient's luminal structure at least as far as a target area of the luminal structure, a balloon catheter with a blind lumen sealed at its distal end and a guidewire lumen extending therethrough to accept the guidewire is inserted into the luminal structure, the blind lumen being adapted to accept a radiation delivery wire into its proximal end.
Inventors
- 👤 Judah Z. Weinberger
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:38
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/10; A61N5/1001; A61N5/1002; A61B; A61B17/00; A61B17/22; A61B2017/22051; A61B2017/22065; A61B2017/22068; A61M; A61M25/00; A61M25/10; A61M2025/1043; A61M2025/1047; A61M2025/1081; A61N5/1007; A61N2005/1008; A61N2005/1019; A61N2005/1021; A61N2005/1092; A61N2005/1094
Claims Analysis
Total Claims: 45
Claim 1
Independent Claim
57 words
An apparatus for use with a guidewire inserted in a luminal structure of a patient for treating a disease process comprising: a balloon catheter with a guidewire lumen extending therethrough adapted to accept a guidewire for guiding the balloon catheter in the patient's luminal structure; said balloon catheter having a radiation producing coating on an internal surface.
Claim 2
Independent Claim
57 words
An apparatus for use with a guidewire inserted in a luminal structure of a patient for treating a disease process comprising: a balloon catheter with a guidewire lumen extending therethrough adapted to accept a guidewire for guiding the balloon catheter in the patient's luminal structure; said balloon catheter having a radiation producing coating on an internal surface.
Claim 3
Dependent Claim
32 words
The apparatus of claim 1, wherein said radiation producing coating includes a material selected from the group consisting of Al-26, Sn-123, K-40, Sr-89, Y-91, Ir-192, Cd-115, P-32, Rb-86, I-125, Pd-103, and Sr-90.
Claim 4
Dependent Claim
14 words
The apparatus of claim 1, wherein said radiation producing coating comprises a lacquer material.
Claim 5
Dependent Claim
14 words
The apparatus of claim 1, wherein said radiation producing coating comprises a glue material.
Claim 6
Dependent Claim
13 words
The apparatus of claim 1, wherein said radiation producing coating comprises acrylic material.
Claim 7
Dependent Claim
13 words
The apparatus of claim 1, wherein said radiation producing coating comprises vinyl material.
Claim 8
Dependent Claim
25 words
The apparatus of claim 1, herein said balloon catheter is formed of a plastic material chosen from the group consisting of polyethylene, PET, and nylon.
Claim 9
Independent Claim
57 words
An apparatus for use with a guidewire inserted into a luminal structure of a patient for treating a disease process comprising: a balloon catheter with a guidewire lumen extending therethrough adapted to accept a guidewire for guiding the balloon catheter in the patient's luminal structure; said balloon catheter having a radiation producing coating on an exterior surface.
Claim 10
Independent Claim
57 words
An apparatus for use with a guidewire inserted into a luminal structure of a patient for treating a disease process comprising: a balloon catheter with a guidewire lumen extending therethrough adapted to accept a guidewire for guiding the balloon catheter in the patient's luminal structure; said balloon catheter having a radiation producing coating on an exterior surface.
Claim 11
Dependent Claim
32 words
The apparatus of claim 8, wherein said radiation producing coating includes a material selected from the group consisting of Al-26, Sn-123, K-40, Sr-89, Y-91, Ir-192, Cd-115, P-32, Rb-86, I-125, Pd-103, and Sr-90.
Claim 12
Dependent Claim
14 words
The apparatus of claim 8, wherein said radiation producing coating comprises a lacquer material.
Claim 13
Dependent Claim
14 words
The apparatus of claim 8, wherein said radiation producing coating comprises a glue material.
Claim 14
Dependent Claim
13 words
The apparatus of claim 8, wherein said radiation producing coating comprises acrylic material.
Claim 15
Dependent Claim
13 words
The apparatus of claim 8, wherein said radiation producing coating comprises vinyl material.
Claim 16
Dependent Claim
25 words
The apparatus of claim 8, Wherein said balloon catheter is formed of a plastic material chosen from the group consisting of polyethylene, PET, and nylon.
Claim 17
Independent Claim
78 words
An apparatus for use with a guidewire inserted into a luminal structure of a patient for treating a disease process comprising: a catheter shaft having a proximal end, a distal end and a guidewire lumen extending therethrough adapted to accept a guidewire for guiding the catheter in the patient's luminal structure, and to allow removal of the guidewire; and a balloon catheter mounted on the catheter and being formed of a flexible material including a radiation producing source.
Claim 18
Independent Claim
78 words
An apparatus for use with a guidewire inserted into a luminal structure of a patient for treating a disease process comprising: a catheter shaft having a proximal end, a distal end and a guidewire lumen extending therethrough adapted to accept a guidewire for guiding the catheter in the patient's luminal structure, and to allow removal of the guidewire; and a balloon catheter mounted on the catheter and being formed of a flexible material including a radiation producing source.
Claim 19
Dependent Claim
25 words
The apparatus of claim 15, wherein said flexible material is formed of a plastic material chosen from the group consisting of polyethylene, PET, and nylon.
Claim 20
Dependent Claim
17 words
The apparatus of claim 15, wherein said plastic material includes a doping of said radiation producing source.
Claim 21
Dependent Claim
24 words
The apparatus of claim 15, wherein said radiation producing source and said plastic material are chemically bonded to each other by a covalent bond.
Claim 22
Dependent Claim
24 words
The apparatus of claim 15, wherein said radiation producing source and said plastic material are chemically bonded to each other by an ionic bond.
Claim 23
Dependent Claim
24 words
The apparatus of claim 15, wherein said radiation producing source and said plastic material are chemically bonded to each other by a biotin-avidin link.
Claim 24
Dependent Claim
22 words
The apparatus of claim 15, wherein said radiation producing source and said plastic material are chemically bonded to each other by coextrusion.
Claim 25
Independent Claim
73 words
An apparatus guided by a guidewire within a luminal structure of a patient for receiving a radiation dose delivery wire with a radiation source attached to its distal end and for treating a disease process comprising: a balloon catheter with a blind lumen sealed at its distal end and a guidewire lumen extending therethrough to accept a guidewire; said blind lumen being adapted to accept said radiation delivery wire into its proximal end.
Claim 26
Independent Claim
73 words
An apparatus guided by a guidewire within a luminal structure of a patient for receiving a radiation dose delivery wire with a radiation source attached to its distal end and for treating a disease process comprising: a balloon catheter with a blind lumen sealed at its distal end and a guidewire lumen extending therethrough to accept a guidewire; said blind lumen being adapted to accept said radiation delivery wire into its proximal end.
Claim 27
Dependent Claim
27 words
The apparatus of claim 22, further comprising means for providing a liquid-tight seal between said radiation dose delivery wire and the proximal end of the blind lumen.
Claim 28
Independent Claim
84 words
An apparatus for use with a guidewire inserted into a luminal structure of a patient for treating a disease process comprising: a radiation dose delivery wire with a radiation source attached to its distal end; and a balloon catheter with a blind lumen sealed at its distal end a guidewire lumen extending therethrough adapted to accept a guidewire for guiding the balloon catheter in the patient's luminal structure; said blind lumen being adapted to accept said radiation dose delivery wire into its proximal end.
Claim 29
Independent Claim
84 words
An apparatus for use with a guidewire inserted into a luminal structure of a patient for treating a disease process comprising: a radiation dose delivery wire with a radiation source attached to its distal end; and a balloon catheter with a blind lumen sealed at its distal end a guidewire lumen extending therethrough adapted to accept a guidewire for guiding the balloon catheter in the patient's luminal structure; said blind lumen being adapted to accept said radiation dose delivery wire into its proximal end.
Claim 30
Dependent Claim
27 words
The apparatus of claim 24, further comprising means for providing a liquid-tight seal between the radiation dose delivery wire and the proximal end of the blind lumen.
Claim 31
Dependent Claim
48 words
The apparatus of claim 25, wherein said means for providing a liquid-tight comprises a liquid-tight radiation delivery wire port connected to the proximal end of the blind lumen, whereby a liquid seal is effectuated between the proximal end of the blind lumen and the radiation dose delivery wire.
Claim 32
Dependent Claim
13 words
The apparatus of claim 24, wherein said radiation source is Ir 192 .
Claim 33
Dependent Claim
13 words
The apparatus of claim 24, wherein said radiation source is I 125 .
Claim 34
Dependent Claim
14 words
The apparatus of claim 24, wherein said ra on source is Pd 103 .
Claim 35
Dependent Claim
14 words
The apparatus of claim 24, wherein said radiation source is in a linear form.
Claim 36
Dependent Claim
16 words
The apparatus of claim 30, wherein said radiation source is between 0.05 and 50 cm long.
Claim 37
Dependent Claim
25 words
The apparatus of claim 24, wherein an outer diameter of the guidewire and an outer diameter of the radiation dose delivery wire are substantially equal.
Claim 38
Dependent Claim
20 words
The apparatus of claim 24, wherein the radiation source has a radioactivity of less than about 10 Curies per centimeter.
Claim 39
Independent Claim
89 words
An apparatus inserted into a luminal structure of a patient for treating a disease process comprising: a guidewire for insertion into the patient's luminal structure at least as far as a target area of the luminal structure; a radiation dose delivery wire with a radiation source attached to its distal end; and a balloon catheter with a blind lumen sealed at its distal end and a guidewire lumen extending therethrough to accept said guidewire; said blind lumen being adapted to accept said radiation delivery wire into its proximal end.
Claim 40
Independent Claim
89 words
An apparatus inserted into a luminal structure of a patient for treating a disease process comprising: a guidewire for insertion into the patient's luminal structure at least as far as a target area of the luminal structure; a radiation dose delivery wire with a radiation source attached to its distal end; and a balloon catheter with a blind lumen sealed at its distal end and a guidewire lumen extending therethrough to accept said guidewire; said blind lumen being adapted to accept said radiation delivery wire into its proximal end.
Claim 41
Independent Claim
157 words
A method of treating a disease process in a patient, comprising: inserting a guidewire into a luminal structure of the patient until a distal end of the guidewire is at least as far into the luminal structure as a predetermined section of the luminal structure; inserting the guidewire into a guidewire lumen of a balloon catheter with a blind lumen; inserting the balloon catheter with the blind lumen into the patient's luminal structure at least as far as the predetermined section of the luminal structure; inserting a radiation dose delivery wire into said blind lumen in said balloon catheter; moving said radiation dose delivery wire into said blind lumen in said balloon catheter; moving said radiation dose delivery wire a predetermined distance into the blind lumen of the balloon catheter for a predetermined period of time; and removing said radiation dose delivery wire from said blind lumen of said balloon catheter after said predetermined period of time.
Claim 42
Independent Claim
157 words
A method of treating a disease process in a patient, comprising: inserting a guidewire into a luminal structure of the patient until a distal end of the guidewire is at least as far into the luminal structure as a predetermined section of the luminal structure; inserting the guidewire into a guidewire lumen of a balloon catheter with a blind lumen; inserting the balloon catheter with the blind lumen into the patient's luminal structure at least as far as the predetermined section of the luminal structure; inserting a radiation dose delivery wire into said blind lumen in said balloon catheter; moving said radiation dose delivery wire into said blind lumen in said balloon catheter; moving said radiation dose delivery wire a predetermined distance into the blind lumen of the balloon catheter for a predetermined period of time; and removing said radiation dose delivery wire from said blind lumen of said balloon catheter after said predetermined period of time.
Claim 43
Dependent Claim
51 words
The method of claim 35, wherein said step of moving said radiation dose delivery wire a predetermined distance into the blind lumen of the balloon catheter for a predetermined period of time results in the distal end of the radiation dose delivery wire being adjacent said predetermined section of luminal structure.
Claim 44
Dependent Claim
59 words
The method of claim 36, wherein said step of moving said radiation dose delivery wire a predetermined distance into the blind lumen of the balloon catheter for a predetermined period of time further comprises determining where the predetermined section of luminal structure is and determining a desired radiation dosage to be delivered to the predetermined section of luminal structure.
Claim 45
Dependent Claim
62 words
The method of claim 37, wherein said step of moving said radiation dose delivery wire a predetermined distance into the blind lumen of the balloon catheter for a predetermined period of time further comprises moving said radiation dose delivery wire back and forth when said distal end of said radiation dose delivery wire is substantially adjacent said predetermined section of luminal structure.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-04-04 | 2003-10-04 | 2004-04-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-04-04 | 2007-10-04 | 2008-04-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-04-04 | 2011-10-04 | 2012-04-04 | $7700.00 | Window Closed / Lapsed |